Search Results - "Spangle JM"

Overexpression of Eaf1, a subunit of the NuA4 lysine acetyltransferase complex, rescues growth defects in the budding yeast H3K36M oncohistone model via histone H4 tail acetylation.

Authors: Jones CY Chen YL Fasken MB et al.

Source: BioRxiv : the preprint server for biology [bioRxiv] 2026 Jun 26. Date of Electronic Publication: 2026 Jun 26.

Publication Type: Journal Article; Preprint

Journal Info: Country of Publication: United States NLM ID: 101680187 Publication Model: Electronic Cited Medium: Internet ISSN: 2692-8205 (Electronic) Linking ISSN: 26928205 NLM ISO Abbreviation: bioRxiv Subsets: PubMed not MEDLINE

Histone H3E50K remodels chromatin to confer oncogenic activity and support an EMT phenotype.

Authors: Sad K Fawwal DV Jones CY et al.

Source: NAR cancer [NAR Cancer] 2025 Feb 03; Vol. 7 (1), pp. zcaf002. Date of Electronic Publication: 2025 Feb 03 (Print Publication: 2025).

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S.

Journal Info: Publisher: Oxford University Press Country of Publication: England NLM ID: 101769553 Publication Model: eCollection Cited Medium: Internet ISSN: 2632-8674 (Electronic) Linking ISSN: 26328674 NLM ISO Abbreviation: NAR Cancer Subsets: MEDLINE

Dynamic In Vivo Mapping of the Methylproteome Using a Chemoenzymatic Approach.

Authors: Farhi J Emenike B Lee RS et al.

Source: Journal of the American Chemical Society [J Am Chem Soc] 2025 Mar 05; Vol. 147 (9), pp. 7214-7230. Date of Electronic Publication: 2025 Feb 25.

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

Journal Info: Publisher: American Chemical Society Country of Publication: United States NLM ID: 7503056 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1520-5126 (Electronic) Linking ISSN: 00027863 NLM ISO Abbreviation: J Am Chem Soc Subsets: MEDLINE

Medulloblastoma and the DNA Damage Response.

Authors: McSwain LF Parwani KK Shahab SW et al.

Source: Frontiers in oncology [Front Oncol] 2022 Jun 07; Vol. 12, pp. 903830. Date of Electronic Publication: 2022 Jun 07 (Print Publication: 2022).

Publication Type: Journal Article; Review

Journal Info: Publisher: Frontiers Research Foundation] Country of Publication: Switzerland NLM ID: 101568867 Publication Model: eCollection Cited Medium: Print ISSN: 2234-943X (Print) Linking ISSN: 2234943X NLM ISO Abbreviation: Front Oncol Subsets: PubMed not MEDLINE

Histone H3 E50K mutation confers oncogenic activity and supports an EMT phenotype.

Authors: Sad K Jones CY Fawwal DV et al.

Source: BioRxiv : the preprint server for biology [bioRxiv] 2024 Aug 01. Date of Electronic Publication: 2024 Aug 01.

Publication Type: Journal Article; Preprint

Journal Info: Country of Publication: United States NLM ID: 101680187 Publication Model: Electronic Cited Medium: Internet ISSN: 2692-8205 (Electronic) Linking ISSN: 26928205 NLM ISO Abbreviation: bioRxiv Subsets: PubMed not MEDLINE

Targeting TRIP13 in favorable histology Wilms tumor with nuclear export inhibitors synergizes with doxorubicin.

Authors: Mittal K Cooper GW Lee BP et al.

Source: Communications biology [Commun Biol] 2024 Apr 08; Vol. 7 (1), pp. 426. Date of Electronic Publication: 2024 Apr 08.

Publication Type: Journal Article; Research Support, N.I.H., Extramural

Journal Info: Publisher: Nature Publishing Group UK Country of Publication: England NLM ID: 101719179 Publication Model: Electronic Cited Medium: Internet ISSN: 2399-3642 (Electronic) Linking ISSN: 23993642 NLM ISO Abbreviation: Commun Biol Subsets: MEDLINE

Tunable fluorescent probes for detecting aldehydes in living systems.

Authors: Wills R Shirke R Hrncir H et al.

Source: Chemical science [Chem Sci] 2024 Mar 19; Vol. 15 (13), pp. 4763-4769. Date of Electronic Publication: 2024 Mar 19 (Print Publication: 2024).

Publication Type: Journal Article

Journal Info: Publisher: Royal Society of Chemistry Country of Publication: England NLM ID: 101545951 Publication Model: eCollection Cited Medium: Print ISSN: 2041-6520 (Print) Linking ISSN: 20416520 NLM ISO Abbreviation: Chem Sci Subsets: PubMed not MEDLINE

Exploring the Molecular Underpinnings of Cancer-Causing Oncohistone Mutants Using Yeast as a Model.

Authors: Zhang X Fawwal DV Spangle JM et al.

Source: Journal of fungi (Basel, Switzerland) [J Fungi (Basel)] 2023 Dec 11; Vol. 9 (12). Date of Electronic Publication: 2023 Dec 11.

Publication Type: Journal Article; Review

Journal Info: Publisher: MDPI AG Country of Publication: Switzerland NLM ID: 101671827 Publication Model: Electronic Cited Medium: Internet ISSN: 2309-608X (Electronic) Linking ISSN: 2309608X NLM ISO Abbreviation: J Fungi (Basel) Subsets: PubMed not MEDLINE

Emerging Role of Epigenetic Modifiers in Breast Cancer Pathogenesis and Therapeutic Response.

Authors: Lee RS Sad K Fawwal DV et al.

Source: Cancers [Cancers (Basel)] 2023 Aug 07; Vol. 15 (15). Date of Electronic Publication: 2023 Aug 07.

Publication Type: Journal Article; Review

Journal Info: Publisher: MDPI Country of Publication: Switzerland NLM ID: 101526829 Publication Model: Electronic Cited Medium: Print ISSN: 2072-6694 (Print) Linking ISSN: 20726694 NLM ISO Abbreviation: Cancers (Basel) Subsets: PubMed not MEDLINE

Identification of ligand-receptor pairs that drive human astrocyte development.

Authors: Voss AJ Lanjewar SN Sampson MM et al.

Source: Nature neuroscience [Nat Neurosci] 2023 Aug; Vol. 26 (8), pp. 1339-1351. Date of Electronic Publication: 2023 Jul 17.

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Nature Publishing Group Country of Publication: United States NLM ID: 9809671 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1546-1726 (Electronic) Linking ISSN: 10976256 NLM ISO Abbreviation: Nat Neurosci Subsets: MEDLINE

Targeting MLL Methyltransferases Enhances the Antitumor Effects of PI3K Inhibition in Hormone Receptor-positive Breast Cancer.

Authors: Jones RB Farhi J Adams M et al.

Source: Cancer research communications [Cancer Res Commun] 2022 Dec 06; Vol. 2 (12), pp. 1569-1578. Date of Electronic Publication: 2022 Dec 06 (Print Publication: 2022).

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, Non-U.S. Gov't

Journal Info: Publisher: American Association for Cancer Research Country of Publication: United States NLM ID: 9918281580506676 Publication Model: eCollection Cited Medium: Internet ISSN: 2767-9764 (Electronic) Linking ISSN: 27679764 NLM ISO Abbreviation: Cancer Res Commun

Adipocyte-mediated epigenomic instability in human T-ALL cells is cytotoxic and phenocopied by epigenetic-modifying drugs.

Authors: Lee M Geitgey DK Hamilton JAG et al.

Source: Frontiers in cell and developmental biology [Front Cell Dev Biol] 2022 Aug 19; Vol. 10, pp. 909557. Date of Electronic Publication: 2022 Aug 19 (Print Publication: 2022).

Publication Type: Journal Article

Journal Info: Publisher: Frontiers Media S.A Country of Publication: Switzerland NLM ID: 101630250 Publication Model: eCollection Cited Medium: Print ISSN: 2296-634X (Print) Linking ISSN: 2296634X NLM ISO Abbreviation: Front Cell Dev Biol Subsets: PubMed not MEDLINE

A Saccharomyces cerevisiae model and screen to define the functional consequences of oncogenic histone missense mutations.

Authors: Lemon LD Kannan S Mo KW et al.

Source: G3 (Bethesda, Md.) [G3 (Bethesda)] 2022 Jul 06; Vol. 12 (7).

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Oxford University Press Country of Publication: England NLM ID: 101566598 Publication Model: Print Cited Medium: Internet ISSN: 2160-1836 (Electronic) Linking ISSN: 21601836 NLM ISO Abbreviation: G3 (Bethesda) Subsets: MEDLINE

Practical advice for mentoring and supporting faculty colleagues in STEM fields: Views from mentor and mentee perspectives.

Authors: Spangle JM Ghalei H Corbett AH

Source: The Journal of biological chemistry [J Biol Chem] 2021 Sep; Vol. 297 (3), pp. 101062. Date of Electronic Publication: 2021 Aug 08.

Publication Type: Journal Article; Research Support, N.I.H., Extramural

Journal Info: Publisher: Elsevier Inc. on behalf of American Society for Biochemistry and Molecular Biology Country of Publication: United States NLM ID: 2985121R Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1083-351X (Electronic) Linking ISSN: 00219258 NLM ISO Abbreviation: J Biol Chem Subsets: MEDLINE

Epigenetic regulation of RTK signaling.

Authors: Spangle JM Roberts TM

Source: Journal of molecular medicine (Berlin, Germany) [J Mol Med (Berl)] 2017 Aug; Vol. 95 (8), pp. 791-798. Date of Electronic Publication: 2017 Jun 06.

Publication Type: Journal Article; Review; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Extramural

Journal Info: Publisher: Springer International Country of Publication: Germany NLM ID: 9504370 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1432-1440 (Electronic) Linking ISSN: 09462716 NLM ISO Abbreviation: J Mol Med (Berl) Subsets: MEDLINE

PIK3CA C-terminal frameshift mutations are novel oncogenic events that sensitize tumors to PI3K-α inhibition.

Authors: Spangle JM Von T Pavlick DC et al.

Source: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2020 Sep 29; Vol. 117 (39), pp. 24427-24433. Date of Electronic Publication: 2020 Sep 14.

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

Journal Info: Publisher: National Academy of Sciences Country of Publication: United States NLM ID: 7505876 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1091-6490 (Electronic) Linking ISSN: 00278424 NLM ISO Abbreviation: Proc Natl Acad Sci U S A Subsets: MEDLINE

The HPV16 E6 oncoprotein causes prolonged receptor protein tyrosine kinase signaling and enhances internalization of phosphorylated receptor species.

Authors: Spangle JM Munger K

Source: PLoS pathogens [PLoS Pathog] 2013 Mar; Vol. 9 (3), pp. e1003237. Date of Electronic Publication: 2013 Mar 14.

Publication Type: Journal Article; Research Support, N.I.H., Extramural

Journal Info: Publisher: Public Library of Science Country of Publication: United States NLM ID: 101238921 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1553-7374 (Electronic) Linking ISSN: 15537366 NLM ISO Abbreviation: PLoS Pathog Subsets: MEDLINE

Interpreting cancer genomes using systematic host network perturbations by tumour virus proteins.

Authors: Rozenblatt-Rosen O Deo RC Padi M et al.

Source: Nature [Nature] 2012 Jul 26; Vol. 487 (7408), pp. 491-5.

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 0410462 Publication Model: Print Cited Medium: Internet ISSN: 1476-4687 (Electronic) Linking ISSN: 00280836 NLM ISO Abbreviation: Nature Subsets: MEDLINE

The emerging role of PI3K/AKT-mediated epigenetic regulation in cancer.

Authors: Spangle JM Roberts TM Zhao JJ

Source: Biochimica et biophysica acta. Reviews on cancer [Biochim Biophys Acta Rev Cancer] 2017 Aug; Vol. 1868 (1), pp. 123-131. Date of Electronic Publication: 2017 Mar 14.

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Review

Journal Info: Publisher: Elsevier Country of Publication: Netherlands NLM ID: 9806362 Publication Model: Print-Electronic Cited Medium: Print ISSN: 0304-419X (Print) Linking ISSN: 0304419X NLM ISO Abbreviation: Biochim Biophys Acta Rev Cancer Subsets: MEDLINE

PI3K-p110α mediates the oncogenic activity induced by loss of the novel tumor suppressor PI3K-p85α.

Authors: Thorpe LM Spangle JM Ohlson CE et al.

Source: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2017 Jul 03; Vol. 114 (27), pp. 7095-7100. Date of Electronic Publication: 2017 Jun 19.

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

Journal Info: Publisher: National Academy of Sciences Country of Publication: United States NLM ID: 7505876 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1091-6490 (Electronic) Linking ISSN: 00278424 NLM ISO Abbreviation: Proc Natl Acad Sci U S A Subsets: MEDLINE