Search Results - "Spiro compounds"

Immunomodulatory Effect of Aza-Spirocyclic Frameworks.

Authors: Prajapati A Tatikonda RR Chada RR et al.

Source: Frontiers in bioscience (Landmark edition) [Front Biosci (Landmark Ed)] 2026 May 18; Vol. 31 (5), pp. 48867.

Publication Type: Journal Article

Journal Info: Publisher: IMR Press Country of Publication: Singapore NLM ID: 101612996 Publication Model: Print Cited Medium: Internet ISSN: 2768-6698 (Electronic) Linking ISSN: 27686698 NLM ISO Abbreviation: Front Biosci (Landmark Ed) Subsets: MEDLINE

AZA Toxin Profiles by LC-HRMS in Shellfish from Šibenik Bay: AZA-2 Predominant Analog.

Authors: Bulić A Pezelj I Ujević I et al.

Source: Molecules (Basel, Switzerland) [Molecules] 2025 Dec 23; Vol. 31 (1). Date of Electronic Publication: 2025 Dec 23.

Publication Type: Journal Article

Journal Info: Publisher: MDPI Country of Publication: Switzerland NLM ID: 100964009 Publication Model: Electronic Cited Medium: Internet ISSN: 1420-3049 (Electronic) Linking ISSN: 14203049 NLM ISO Abbreviation: Molecules Subsets: MEDLINE

Comparison of effect and mechanism between nalfurafine hydrochloride and narrow-band ultraviolet B phototherapy in the treatment of pruritus in hemodialysis patients.

Authors: Choi S Shin DH Kim JS et al.

Source: Annals of medicine [Ann Med] 2025 Dec; Vol. 57 (1), pp. 2460766. Date of Electronic Publication: 2025 Feb 13.

Publication Type: Journal Article; Comparative Study

Journal Info: Publisher: Informa Healthcare Country of Publication: England NLM ID: 8906388 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1365-2060 (Electronic) Linking ISSN: 07853890 NLM ISO Abbreviation: Ann Med Subsets: MEDLINE

Spiroindoline quinazolinedione derivatives as inhibitors of P-glycoprotein: potential agents for overcoming multidrug resistance in cancer therapy.

Authors: Moosavi F Divar M Khabnadideh S et al.

Source: Molecular diversity [Mol Divers] 2025 Dec; Vol. 29 (6), pp. 6519-6532. Date of Electronic Publication: 2025 Mar 19.

Publication Type: Journal Article

Journal Info: Publisher: ESCOM Science Publishers Country of Publication: Netherlands NLM ID: 9516534 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1573-501X (Electronic) Linking ISSN: 13811991 NLM ISO Abbreviation: Mol Divers Subsets: MEDLINE

A Stereospecific Synthesis and In Vitro Anti-Influenza H1N1 Properties of Lithocholic Acid-Based Spiro-1,2,4-trioxolane.

Authors: Smirnova I Lobov A Zakirova L et al.

Source: Molecules (Basel, Switzerland) [Molecules] 2025 Dec 01; Vol. 30 (23). Date of Electronic Publication: 2025 Dec 01.

Publication Type: Journal Article

Journal Info: Publisher: MDPI Country of Publication: Switzerland NLM ID: 100964009 Publication Model: Electronic Cited Medium: Internet ISSN: 1420-3049 (Electronic) Linking ISSN: 14203049 NLM ISO Abbreviation: Molecules Subsets: MEDLINE

1-Styryl-1,3-diketones in the synthesis of spiro[oxindole-3,2'-pyrrolidines] with notable anticancer activity.

Authors: Zimnitskiy NS Korotaev VY Ulitko MV et al.

Source: Molecular diversity [Mol Divers] 2025 Dec; Vol. 29 (6), pp. 5979-5992. Date of Electronic Publication: 2025 Feb 04.

Publication Type: Journal Article

Journal Info: Publisher: ESCOM Science Publishers Country of Publication: Netherlands NLM ID: 9516534 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1573-501X (Electronic) Linking ISSN: 13811991 NLM ISO Abbreviation: Mol Divers Subsets: MEDLINE

Design and synthesis of 1,4,8-triazaspiro[4.5]decan-2-one derivatives as novel mitochondrial permeability transition pore inhibitors.

Authors: Albanese V Pedriali G Fabbri M et al.

Source: Journal of enzyme inhibition and medicinal chemistry [J Enzyme Inhib Med Chem] 2025 Dec; Vol. 40 (1), pp. 2505907. Date of Electronic Publication: 2025 May 21.

Publication Type: Journal Article

Journal Info: Publisher: Taylor & Francis Country of Publication: England NLM ID: 101150203 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1475-6374 (Electronic) Linking ISSN: 14756366 NLM ISO Abbreviation: J Enzyme Inhib Med Chem Subsets: MEDLINE

Synthesis of xanthenone fused spiro pyrrolidine oxindoles via multicomponent [3 + 2] cycloaddition reactions.

Authors: Paramasivam G Palanichamy B Paramathevar N

Source: Molecular diversity [Mol Divers] 2025 Dec; Vol. 29 (6), pp. 6533-6542. Date of Electronic Publication: 2025 Mar 21.

Publication Type: Journal Article

Journal Info: Publisher: ESCOM Science Publishers Country of Publication: Netherlands NLM ID: 9516534 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1573-501X (Electronic) Linking ISSN: 13811991 NLM ISO Abbreviation: Mol Divers Subsets: MEDLINE

In Silico Molecular Docking of 2-Hydroxyanthraquinone-Substituted Spiro-/Ansa Cyclotriphosphazenes: Targeting Apoptosis via Heat Shock Protein Modulation in Breast and Colon Cancer Cells.

Authors: Mesci S Yazgan B Demir Demirel G et al.

Source: Biotechnology and applied biochemistry [Biotechnol Appl Biochem] 2025 Dec; Vol. 72 (6), pp. 1618-1632. Date of Electronic Publication: 2025 Apr 29.

Publication Type: Journal Article

Journal Info: Publisher: Wiley-Blackwell Country of Publication: United States NLM ID: 8609465 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1470-8744 (Electronic) Linking ISSN: 08854513 NLM ISO Abbreviation: Biotechnol Appl Biochem Subsets: MEDLINE

Novel spiroisatin-pyranopyrazole hybrids as anticancer agents with TrkC inhibitory potential.

Authors: Mohammadi S Mortazavi M Poustforoosh A et al.

Source: Journal of biomolecular structure & dynamics [J Biomol Struct Dyn] 2025 Nov; Vol. 43 (18), pp. 10931-10944. Date of Electronic Publication: 2025 Mar 02.

Publication Type: Journal Article

Journal Info: Publisher: Taylor & Francis Country of Publication: England NLM ID: 8404176 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1538-0254 (Electronic) Linking ISSN: 07391102 NLM ISO Abbreviation: J Biomol Struct Dyn Subsets: MEDLINE

Effect of Oliceridine on Sufentanil-Induced Cough During General Anesthesia: A Prospective Randomized Controlled Clinical Study.

Authors: Gong WY Li CG Ge CL et al.

Source: Drug design, development and therapy [Drug Des Devel Ther] 2025 Dec 17; Vol. 19, pp. 11317-11324. Date of Electronic Publication: 2025 Dec 17 (Print Publication: 2025).

Publication Type: Journal Article; Randomized Controlled Trial

Journal Info: Publisher: Dove Press Limited Country of Publication: New Zealand NLM ID: 101475745 Publication Model: eCollection Cited Medium: Internet ISSN: 1177-8881 (Electronic) Linking ISSN: 11778881 NLM ISO Abbreviation: Drug Des Devel Ther Subsets: MEDLINE

A Medicinal Chemistry Perspective on Anticonvulsant Drug Design: Targets, Mechanisms, and Spiro Compounds.

Authors: Hamid GA Elmasry GF El-Moghazy SM et al.

Source: Drug development research [Drug Dev Res] 2026 Jun; Vol. 87 (4), pp. e70317.

Publication Type: Journal Article; Review

Journal Info: Publisher: Wiley-Liss Country of Publication: United States NLM ID: 8204468 Publication Model: Print Cited Medium: Internet ISSN: 1098-2299 (Electronic) Linking ISSN: 02724391 NLM ISO Abbreviation: Drug Dev Res Subsets: MEDLINE

Chromenone coupled to spiro[indene-2,3'-pyrrolizine]-1,3-diones as a novel class of α-glucosidase inhibitor.

Authors: Eisayi A Fathi A Ramezanpour S et al.

Source: Bioorganic chemistry [Bioorg Chem] 2026 Jul 15; Vol. 176, pp. 109739. Date of Electronic Publication: 2026 Mar 19.

Publication Type: Journal Article

Journal Info: Publisher: Elsevier Country of Publication: United States NLM ID: 1303703 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1090-2120 (Electronic) Linking ISSN: 00452068 NLM ISO Abbreviation: Bioorg Chem Subsets: MEDLINE

First Total Synthesis of Cryptolaevilactones, Unique Spiromeroterpenoids.

Authors: Nishida T Miura Y Saito Y et al.

Source: The Journal of organic chemistry [J Org Chem] 2026 Jul 10; Vol. 91 (27), pp. 9401-9408. Date of Electronic Publication: 2026 Jun 29.

Publication Type: Journal Article

Journal Info: Publisher: American Chemical Society Country of Publication: United States NLM ID: 2985193R Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1520-6904 (Electronic) Linking ISSN: 00223263 NLM ISO Abbreviation: J Org Chem Subsets: MEDLINE

Identification of Fluoro-methoxy-phenyl-substituted N-sulfonylpiperidine-mono-spiro-1,2,4,5-tetraoxanes as Multispecies-targeting Molecules.

Authors: Tiwari MK Bakun P Forest E et al.

Source: European journal of medicinal chemistry [Eur J Med Chem] 2026 Jul 05; Vol. 311, pp. 118826. Date of Electronic Publication: 2026 Apr 02.

Publication Type: Journal Article

Journal Info: Publisher: Editions Scientifiques Elsevier Country of Publication: France NLM ID: 0420510 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1768-3254 (Electronic) Linking ISSN: 02235234 NLM ISO Abbreviation: Eur J Med Chem Subsets: MEDLINE

Green diastereoselective synthesis of spiropyrrolidines by the one-pot three component reaction of isatins, THβC and 5-arylidene-thiazolidine-2,4-diones and its anticancer evaluation.

Authors: Mohan M Sudhina S Meenakshy CB et al.

Source: Bioorganic chemistry [Bioorg Chem] 2026 Jul 05; Vol. 175, pp. 109786. Date of Electronic Publication: 2026 Mar 23.

Publication Type: Journal Article

Journal Info: Publisher: Elsevier Country of Publication: United States NLM ID: 1303703 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1090-2120 (Electronic) Linking ISSN: 00452068 NLM ISO Abbreviation: Bioorg Chem Subsets: MEDLINE

Fine-tuning the combination of novel spirocyclic capping moieties and heterocyclic zinc binding groups for selective HDAC6 inhibition: design, synthesis, kinetic and biological studies.

Authors: Barone S Bello I Filocamo G et al.

Source: European journal of medicinal chemistry [Eur J Med Chem] 2026 Jul 05; Vol. 311, pp. 118806. Date of Electronic Publication: 2026 Mar 29.

Publication Type: Journal Article

Journal Info: Publisher: Editions Scientifiques Elsevier Country of Publication: France NLM ID: 0420510 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1768-3254 (Electronic) Linking ISSN: 02235234 NLM ISO Abbreviation: Eur J Med Chem Subsets: MEDLINE

Therapeutic potential of spirocyclopropyl oxindoles: latest developments in drug discovery.

Authors: Dastari S Shankaraiah N

Source: Future medicinal chemistry [Future Med Chem] 2026 Jul; Vol. 18 (13), pp. 1753-1767. Date of Electronic Publication: 2026 May 27.

Publication Type: Journal Article; Review; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Taylor & Francis Country of Publication: England NLM ID: 101511162 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1756-8927 (Electronic) Linking ISSN: 17568919 NLM ISO Abbreviation: Future Med Chem Subsets: MEDLINE

Spirocyclic polycyclic polyprenylated acylphloroglucinols from Hypericum henryi and their anti-inflammatory activity.

Authors: Yue T Zhang J Wang X et al.

Source: Fitoterapia [Fitoterapia] 2026 Jul; Vol. 192, pp. 107277. Date of Electronic Publication: 2026 May 11.

Publication Type: Journal Article

Journal Info: Publisher: Elsevier Country of Publication: Netherlands NLM ID: 16930290R Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-6971 (Electronic) Linking ISSN: 0367326X NLM ISO Abbreviation: Fitoterapia Subsets: MEDLINE

Azaspiromycin and pentalenolactone derivatives with insecticidal activities against Plutella xylostella from Streptomyces huasconensis NA10.

Authors: Bai Y Tan M Sun H et al.

Source: Pest management science [Pest Manag Sci] 2026 Jul; Vol. 82 (7), pp. 6684-6697. Date of Electronic Publication: 2026 Mar 20.

Publication Type: Journal Article

Journal Info: Publisher: Published for SCI by Wiley Country of Publication: England NLM ID: 100898744 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1526-4998 (Electronic) Linking ISSN: 1526498X NLM ISO Abbreviation: Pest Manag Sci Subsets: MEDLINE