Search Results - "Splinter PL"

Mitochondrial RNA cytosolic leakage drives the SASP.

Authors: Victorelli S Eppard M Martini H et al.

Source: Nature communications [Nat Commun] 2025 Dec 15; Vol. 16 (1), pp. 10992. Date of Electronic Publication: 2025 Dec 15.

Publication Type: Journal Article

Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE

Differential MYC Phosphorylation Drives the Divergent Cholangiocyte Response to Stress.

Authors: O'Hara SP Splinter PL Felzen A et al.

Source: Cellular and molecular gastroenterology and hepatology [Cell Mol Gastroenterol Hepatol] 2025; Vol. 19 (10), pp. 101547. Date of Electronic Publication: 2025 May 29.

Publication Type: Journal Article

Journal Info: Publisher: American Gastroenterological Association Country of Publication: United States NLM ID: 101648302 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2352-345X (Electronic) Linking ISSN: 2352345X NLM ISO Abbreviation: Cell Mol Gastroenterol Hepatol Subsets: MEDLINE

Mitochondrial RNA cytosolic leakage drives the SASP.

Authors: Victorelli S Eppard M Woo SH et al.

Source: Research square [Res Sq] 2024 Aug 27. Date of Electronic Publication: 2024 Aug 27.

Publication Type: Journal Article; Preprint

Journal Info: Country of Publication: United States NLM ID: 101768035 Publication Model: Electronic Cited Medium: Internet ISSN: 2693-5015 (Electronic) Linking ISSN: 26935015 NLM ISO Abbreviation: Res Sq Subsets: PubMed not MEDLINE

Senescent cholangiocytes release extracellular vesicles that alter target cell phenotype via the epidermal growth factor receptor.

Authors: Al Suraih MS Trussoni CE Splinter PL et al.

Source: Liver international : official journal of the International Association for the Study of the Liver [Liver Int] 2020 Oct; Vol. 40 (10), pp. 2455-2468. Date of Electronic Publication: 2020 Jul 07.

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Wiley-Blackwell Country of Publication: United States NLM ID: 101160857 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1478-3231 (Electronic) Linking ISSN: 14783223 NLM ISO Abbreviation: Liver Int Subsets: MEDLINE

The Epigenetic Reader, Bromodomain Containing 2, Mediates Cholangiocyte Senescence via Interaction With ETS Proto-Oncogene 1.

Authors: Kang JH Splinter PL Trussoni CE et al.

Source: Gastroenterology [Gastroenterology] 2023 Jul; Vol. 165 (1), pp. 228-243.e2. Date of Electronic Publication: 2023 Apr 12.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Extramural

Journal Info: Publisher: W.B. Saunders Country of Publication: United States NLM ID: 0374630 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1528-0012 (Electronic) Linking ISSN: 00165085 NLM ISO Abbreviation: Gastroenterology Subsets: MEDLINE

Lipopolysaccharide (LPS)-Induced Biliary Epithelial Cell NRas Activation Requires Epidermal Growth Factor Receptor (EGFR).

Authors: Trussoni CE Tabibian JH Splinter PL et al.

Source: PloS one [PLoS One] 2015 Apr 27; Vol. 10 (4), pp. e0125793. Date of Electronic Publication: 2015 Apr 27 (Print Publication: 2015).

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection Cited Medium: Internet ISSN: 1932-6203 (Electronic) Linking ISSN: 19326203 NLM ISO Abbreviation: PLoS One Subsets: MEDLINE

Ciliary subcellular localization of TGR5 determines the cholangiocyte functional response to bile acid signaling.

Authors: Masyuk AI Huang BQ Radtke BN et al.

Source: American journal of physiology. Gastrointestinal and liver physiology [Am J Physiol Gastrointest Liver Physiol] 2013 Jun 01; Vol. 304 (11), pp. G1013-24. Date of Electronic Publication: 2013 Apr 11.

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

Journal Info: Publisher: American Physiological Society Country of Publication: United States NLM ID: 100901227 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1522-1547 (Electronic) Linking ISSN: 01931857 NLM ISO Abbreviation: Am J Physiol Gastrointest Liver Physiol Subsets: MEDLINE

Biliary exosomes influence cholangiocyte regulatory mechanisms and proliferation through interaction with primary cilia.

Authors: Masyuk AI Huang BQ Ward CJ et al.

Source: American journal of physiology. Gastrointestinal and liver physiology [Am J Physiol Gastrointest Liver Physiol] 2010 Oct; Vol. 299 (4), pp. G990-9. Date of Electronic Publication: 2010 Jul 15.

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

Journal Info: Publisher: American Physiological Society Country of Publication: United States NLM ID: 100901227 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1522-1547 (Electronic) Linking ISSN: 01931857 NLM ISO Abbreviation: Am J Physiol Gastrointest Liver Physiol Subsets: MEDLINE

The transcription factor ETS1 promotes apoptosis resistance of senescent cholangiocytes by epigenetically up-regulating the apoptosis suppressor BCL2L1.

Authors: O'Hara SP Splinter PL Trussoni CE et al.

Source: The Journal of biological chemistry [J Biol Chem] 2019 Dec 06; Vol. 294 (49), pp. 18698-18713. Date of Electronic Publication: 2019 Oct 28.

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Elsevier Inc. on behalf of American Society for Biochemistry and Molecular Biology Country of Publication: United States NLM ID: 2985121R Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1083-351X (Electronic) Linking ISSN: 00219258 NLM ISO Abbreviation: J Biol Chem Subsets: MEDLINE

Cholangiocyte primary cilia are chemosensory organelles that detect biliary nucleotides via P2Y12 purinergic receptors.

Authors: Masyuk AI Gradilone SA Banales JM et al.

Source: American journal of physiology. Gastrointestinal and liver physiology [Am J Physiol Gastrointest Liver Physiol] 2008 Oct; Vol. 295 (4), pp. G725-34. Date of Electronic Publication: 2008 Aug 07.

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

Journal Info: Publisher: American Physiological Society Country of Publication: United States NLM ID: 100901227 Publication Model: Print-Electronic Cited Medium: Print ISSN: 0193-1857 (Print) Linking ISSN: 01931857 NLM ISO Abbreviation: Am J Physiol Gastrointest Liver Physiol Subsets: MEDLINE

Expression and subcellular localization of aquaporin water channels in the polarized hepatocyte cell line, WIF-B.

Authors: Gradilone SA Tietz PS Splinter PL et al.

Source: BMC physiology [BMC Physiol] 2005 Aug 18; Vol. 5, pp. 13. Date of Electronic Publication: 2005 Aug 18.

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.

Journal Info: Publisher: BioMed Central Country of Publication: England NLM ID: 101088687 Publication Model: Electronic Cited Medium: Internet ISSN: 1472-6793 (Electronic) Linking ISSN: 14726793 NLM ISO Abbreviation: BMC Physiol Subsets: MEDLINE

Somatostatin stimulates ductal bile absorption and inhibits ductal bile secretion in mice via SSTR2 on cholangiocytes.

Authors: Gong AY Tietz PS Muff MA et al.

Source: American journal of physiology. Cell physiology [Am J Physiol Cell Physiol] 2003 May; Vol. 284 (5), pp. C1205-14.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.

Journal Info: Publisher: American Physiological Society Country of Publication: United States NLM ID: 100901225 Publication Model: Print Cited Medium: Print ISSN: 0363-6143 (Print) Linking ISSN: 03636143 NLM ISO Abbreviation: Am J Physiol Cell Physiol Subsets: MEDLINE

Intrahepatic bile ducts transport water in response to absorbed glucose.

Authors: Masyuk AI Masyuk TV Tietz PS et al.

Source: American journal of physiology. Cell physiology [Am J Physiol Cell Physiol] 2002 Sep; Vol. 283 (3), pp. C785-91.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.

Journal Info: Publisher: American Physiological Society Country of Publication: United States NLM ID: 100901225 Publication Model: Print Cited Medium: Print ISSN: 0363-6143 (Print) Linking ISSN: 03636143 NLM ISO Abbreviation: Am J Physiol Cell Physiol Subsets: MEDLINE

Channel-mediated water movement across enclosed or perfused mouse intrahepatic bile duct units.

Authors: Gong AY Masyuk AI Splinter PL et al.

Source: American journal of physiology. Cell physiology [Am J Physiol Cell Physiol] 2002 Jul; Vol. 283 (1), pp. C338-46.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.

Journal Info: Publisher: American Physiological Society Country of Publication: United States NLM ID: 100901225 Publication Model: Print Cited Medium: Print ISSN: 0363-6143 (Print) Linking ISSN: 03636143 NLM ISO Abbreviation: Am J Physiol Cell Physiol Subsets: MEDLINE

Macrophages contribute to the pathogenesis of sclerosing cholangitis in mice.

Authors: Guicciardi ME Trussoni CE Krishnan A et al.

Source: Journal of hepatology [J Hepatol] 2018 Sep; Vol. 69 (3), pp. 676-686. Date of Electronic Publication: 2018 May 24.

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Elsevier Country of Publication: Netherlands NLM ID: 8503886 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1600-0641 (Electronic) Linking ISSN: 01688278 NLM ISO Abbreviation: J Hepatol Subsets: MEDLINE

Targeting senescent cholangiocytes and activated fibroblasts with B-cell lymphoma-extra large inhibitors ameliorates fibrosis in multidrug resistance 2 gene knockout (Mdr2^-/- ) mice.

Authors: Moncsek A Al-Suraih MS Trussoni CE et al.

Source: Hepatology (Baltimore, Md.) [Hepatology] 2018 Jan; Vol. 67 (1), pp. 247-259. Date of Electronic Publication: 2017 Nov 29.

Publication Type: Comparative Study; Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Wolters Kluwer Health, Inc Country of Publication: United States NLM ID: 8302946 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1527-3350 (Electronic) Linking ISSN: 02709139 NLM ISO Abbreviation: Hepatology Subsets: MEDLINE

ETS Proto-oncogene 1 Transcriptionally Up-regulates the Cholangiocyte Senescence-associated Protein Cyclin-dependent Kinase Inhibitor 2A.

Authors: O'Hara SP Splinter PL Trussoni CE et al.

Source: The Journal of biological chemistry [J Biol Chem] 2017 Mar 24; Vol. 292 (12), pp. 4833-4846. Date of Electronic Publication: 2017 Feb 08.

Publication Type: Journal Article

Journal Info: Publisher: Elsevier Inc. on behalf of American Society for Biochemistry and Molecular Biology Country of Publication: United States NLM ID: 2985121R Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1083-351X (Electronic) Linking ISSN: 00219258 NLM ISO Abbreviation: J Biol Chem Subsets: MEDLINE

Absence of the intestinal microbiota exacerbates hepatobiliary disease in a murine model of primary sclerosing cholangitis.

Authors: Tabibian JH O'Hara SP Trussoni CE et al.

Source: Hepatology (Baltimore, Md.) [Hepatology] 2016 Jan; Vol. 63 (1), pp. 185-96. Date of Electronic Publication: 2015 Aug 10.

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Wolters Kluwer Health, Inc Country of Publication: United States NLM ID: 8302946 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1527-3350 (Electronic) Linking ISSN: 02709139 NLM ISO Abbreviation: Hepatology Subsets: MEDLINE

Characterization of cultured cholangiocytes isolated from livers of patients with primary sclerosing cholangitis.

Authors: Tabibian JH Trussoni CE O'Hara SP et al.

Source: Laboratory investigation; a journal of technical methods and pathology [Lab Invest] 2014 Oct; Vol. 94 (10), pp. 1126-33. Date of Electronic Publication: 2014 Jul 21.

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Elsevier Inc Country of Publication: United States NLM ID: 0376617 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1530-0307 (Electronic) Linking ISSN: 00236837 NLM ISO Abbreviation: Lab Invest Subsets: MEDLINE

Cholangiocyte senescence by way of N-ras activation is a characteristic of primary sclerosing cholangitis.

Authors: Tabibian JH O'Hara SP Splinter PL et al.

Source: Hepatology (Baltimore, Md.) [Hepatology] 2014 Jun; Vol. 59 (6), pp. 2263-75. Date of Electronic Publication: 2014 Apr 25.

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Wolters Kluwer Health, Inc Country of Publication: United States NLM ID: 8302946 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1527-3350 (Electronic) Linking ISSN: 02709139 NLM ISO Abbreviation: Hepatology Subsets: MEDLINE