Search Results - "Spring, David R."

Advances in the Release of Amide‐Containing Molecules.

Authors: Wharton, Thomas Spring, David R.

Source: Chemistry - A European Journal. 3/17/2025, Vol. 31 Issue 16, p1-7. 7p.

Recent progress towards catalytic asymmetric construction of inherently chiral scaffolds.

Authors: Zhu, Kai Spring, David R. Shi, Bing-Feng et al.

Source: Chemical Society Reviews. 12/7/2025, Vol. 54 Issue 23, p10856-10879. 24p.

Subjects: Asymmetric synthesis, Chirality, Molecular recognition, Materials science, Pharmaceutical chemistry, Enantioselective catalysis

Tryptophan in Multicomponent Petasis Reactions for Peptide Stapling and Late‐Stage Functionalisation.

Authors: Krajcovicova, Sona Spring, David R.

Source: Angewandte Chemie International Edition. 8/21/2023, Vol. 62 Issue 34, p1-9. 9p.

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Unlocking Amides: A General Method for the Self‐Immolative Release of Amide‐Containing Molecules.

Authors: Wharton, Thomas Crawshay‐Williams, Felicity Schober, Tim et al.

Source: Angewandte Chemie International Edition; Apr2024, Vol. 63 Issue 18, p1-8, 8p

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Diversity-oriented synthesis of biaryl-containing medium rings using a one bead/one stock solution platform.

Authors: Spring, David R. Krishnan, Shyam Blackwell, Helen E.

Source: Journal of the American Chemical Society; February 20 2002, Vol. 124 Issue 7, p1354-1363, 10p

The role of chemical synthesis in developing RiPP antibiotics.

Authors: Rowe, Sam M. Spring, David R.

Source: Chemical Society Reviews. 4/7/2021, Vol. 50 Issue 7, p4245-4258. 14p.

Subjects: Chemical synthesis, Peptide antibiotics, Antibiotics, Peptide drugs, Anti-infective agents, Drug resistance in microorganisms

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Expeditious Total Synthesis of Hemiasterlin through a Convergent Multicomponent Strategy and Its Use in Targeted Cancer Therapeutics.

Authors: Charoenpattarapreeda, Jiraborrirak Walsh, Stephen J. Carroll, Jason S. et al.

Source: Angewandte Chemie International Edition; 12/14/2020, Vol. 59 Issue 51, p23045-23050, 6p

Strategies for the Diversity-Oriented Synthesis of Macrocycles.

Authors: Mortensen, Kim T. Osberger, Thomas J. King, Thomas A. et al.

Source: Chemical Reviews; 9/11/2019, Vol. 119 Issue 17, p10288-10317, 30p

Cycloaddition Strategies for the Synthesis of Diverse Heterocyclic Spirocycles for Fragment‐Based Drug Discovery.

Authors: King, Thomas A. Stewart, Hannah L. Mortensen, Kim T. et al.

Source: European Journal of Organic Chemistry; 9/1/2019, Vol. 2019 Issue 31/32, p5219-5229, 11p

Synthesis of Structurally Diverse N‐Substituted Quaternary‐Carbon‐Containing Small Molecules from α,α‐Disubstituted Propargyl Amino Esters.

Authors: Mateu, Natalia Kidd, Sarah L. Kalash, Leen et al.

Source: Chemistry - A European Journal; 9/12/2018, Vol. 24 Issue 51, p13681-13687, 7p

Targeting the Genome-Stability Hub Ctf4 by Stapled-Peptide Design.

Authors: Wu, Yuteng Villa, Fabrizio Maman, Joseph et al.

Source: Angewandte Chemie International Edition; 10/9/2017, Vol. 56 Issue 42, p12866-12872, 7p

Towards diversity-oriented, stereoselective syntheses of biaryl- or bis(aryl)metal-containing medium rings.

Authors: Spring, David R. Krishnan, Shyam Schreiber, Stuart L.

Source: Journal of the American Chemical Society; June 14 2000, Vol. 122 Issue 23, p5656-5657, 2p

Arene C-H functionalisation using a removable/modifiable or a traceless directing group strategy.

Authors: Fengzhi Zhang Spring, David R.

Source: Chemical Society Reviews. 2014, Vol. 43 Issue 20, p6906-6919. 14p.

Subjects: Carbon-hydrogen bonds, Moieties (Chemistry), Aromatic compounds, Scission (Chemistry), Regioselectivity (Chemistry), Alkylation

Macrocyclized Extended Peptides: Inhibiting the Substrate-Recognition Domain of Tankyrase.

Authors: Wenshu Xu Yu Heng Lau Fischer, Gerhard et al.

Source: Journal of the American Chemical Society; 2/15/2017, Vol. 139 Issue 6, p2245-2256, 11p

Development of Cell-Permeable, Non-Helical Constrained Peptides to Target a Key Protein-Protein Interaction in Ovarian Cancer.

Authors: Wu, Yuteng Sore, Hannah F. Spring, David R. et al.

Source: Angewandte Chemie International Edition; 1/9/2017, Vol. 56 Issue 2, p524-529, 6p