Search Results - "Spring DR"

Recent advances in antibody-drug conjugates.

Authors: Sydenham JD Wharton T Spring DR

Source: Current opinion in chemical biology [Curr Opin Chem Biol] 2026 Jul 16; Vol. 94, pp. 102727. Date of Electronic Publication: 2026 Jul 16.

Publication Type: Journal Article; Review

Journal Info: Publisher: Elsevier Country of Publication: England NLM ID: 9811312 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-0402 (Electronic) Linking ISSN: 13675931 NLM ISO Abbreviation: Curr Opin Chem Biol Subsets: MEDLINE

Peptide Marriages: Modular Assembly of Multi-Agonist Therapeutics.

Authors: Kostadinova KA Venne JL Krajcovicova S et al.

Source: Chemistry (Weinheim an der Bergstrasse, Germany) [Chemistry] 2026 Jun 18, pp. e71280. Date of Electronic Publication: 2026 Jun 18.

Publication Type: Journal Article

Journal Info: Publisher: Wiley-VCH Country of Publication: Germany NLM ID: 9513783 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1521-3765 (Electronic) Linking ISSN: 09476539 NLM ISO Abbreviation: Chemistry Subsets: MEDLINE

Multicomponent Stapling of Glucagon-Like Peptide-1 Enables Receptor-Guided PROTAC Delivery.

Authors: Venne JL Krajcovicova S Davies G et al.

Source: Angewandte Chemie (International ed. in English) [Angew Chem Int Ed Engl] 2026 Jun 12, pp. e9595531. Date of Electronic Publication: 2026 Jun 12.

Publication Type: Journal Article

Journal Info: Publisher: Wiley-VCH Country of Publication: Germany NLM ID: 0370543 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1521-3773 (Electronic) Linking ISSN: 14337851 NLM ISO Abbreviation: Angew Chem Int Ed Engl Subsets: MEDLINE

On-resin assembly of cysteine-reactive linkers for controlled site-selective antibody bioconjugation.

Authors: Krajcovicova S Wharton T Spring DR

Source: Nature protocols [Nat Protoc] 2026 Jun 09. Date of Electronic Publication: 2026 Jun 09.

Publication Type: Journal Article; Review

Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101284307 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1750-2799 (Electronic) Linking ISSN: 17502799 NLM ISO Abbreviation: Nat Protoc Subsets: MEDLINE

Boosting peptide half-life: enabling efficient generation of Fc-peptide conjugates.

Authors: Park M Dannheim FM Papworth MA et al.

Source: Chemical science [Chem Sci] 2026 May 29; Vol. 17 (27), pp. 13454-13464. Date of Electronic Publication: 2026 May 29 (Print Publication: 2026).

Publication Type: Journal Article

Journal Info: Publisher: Royal Society of Chemistry Country of Publication: England NLM ID: 101545951 Publication Model: eCollection Cited Medium: Print ISSN: 2041-6520 (Print) Linking ISSN: 20416520 NLM ISO Abbreviation: Chem Sci Subsets: PubMed not MEDLINE

Targeting a Pleckstrin Homology Domain with a Lysine-Reactive Covalent Binder.

Authors: West RM Bizga Nicolescu RC Brear P et al.

Source: Journal of medicinal chemistry [J Med Chem] 2026 May 28; Vol. 69 (10), pp. 12099-12121. Date of Electronic Publication: 2026 May 14.

Publication Type: Journal Article

Journal Info: Publisher: American Chemical Society Country of Publication: United States NLM ID: 9716531 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1520-4804 (Electronic) Linking ISSN: 00222623 NLM ISO Abbreviation: J Med Chem Subsets: MEDLINE

Development of D-box peptides to inhibit the anaphase-promoting complex/cyclosome.

Authors: Eapen R Okoye C Stubbs C et al.

Source: ELife [Elife] 2025 Sep 01; Vol. 14. Date of Electronic Publication: 2025 Sep 01.

Publication Type: Journal Article

Journal Info: Publisher: eLife Sciences Publications, Ltd Country of Publication: England NLM ID: 101579614 Publication Model: Electronic Cited Medium: Internet ISSN: 2050-084X (Electronic) Linking ISSN: 2050084X NLM ISO Abbreviation: Elife Subsets: MEDLINE

Methods for the Generation of Single-Payload Antibody-Drug Conjugates.

Authors: Wharton T Spring DR

Source: ChemMedChem [ChemMedChem] 2025 May 19; Vol. 20 (10), pp. e202500132. Date of Electronic Publication: 2025 Mar 19.

Publication Type: Journal Article

Journal Info: Publisher: Wiley-VCH Country of Publication: Germany NLM ID: 101259013 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1860-7187 (Electronic) Linking ISSN: 18607179 NLM ISO Abbreviation: ChemMedChem Subsets: MEDLINE

Towards the targeted protein degradation of CK2: design and synthesis of CAM4066-based PROTACs.

Authors: Day-Riley S Krajcovicova S Sokhal AR et al.

Source: Beilstein journal of organic chemistry [Beilstein J Org Chem] 2026 Apr 22; Vol. 22, pp. 611-619. Date of Electronic Publication: 2026 Apr 22 (Print Publication: 2026).

Publication Type: Letter

Journal Info: Publisher: Beilstein-Institut Country of Publication: Germany NLM ID: 101250746 Publication Model: eCollection Cited Medium: Print ISSN: 1860-5397 (Print) Linking ISSN: 18605397 NLM ISO Abbreviation: Beilstein J Org Chem Subsets: PubMed not MEDLINE

Bismuth Bicycles.

Authors: Voss S Sagar A Tiberghien A et al.

Source: Journal of peptide science : an official publication of the European Peptide Society [J Pept Sci] 2026 Mar; Vol. 32 (3), pp. e70071.

Publication Type: Journal Article; Review

Journal Info: Publisher: John Wiley & Sons Country of Publication: England NLM ID: 9506309 Publication Model: Print Cited Medium: Internet ISSN: 1099-1387 (Electronic) Linking ISSN: 10752617 NLM ISO Abbreviation: J Pept Sci Subsets: MEDLINE

Pseudomonas aeruginosa acyl-CoA dehydrogenases and structure-guided inversion of their substrate specificity.

Authors: Wang M Medarametla P Kronenberger T et al.

Source: Nature communications [Nat Commun] 2025 Mar 08; Vol. 16 (1), pp. 2334. Date of Electronic Publication: 2025 Mar 08.

Publication Type: Journal Article

Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE

Publisher Correction: Novel immunotherapeutics against LGR5 to target multiple cancer types.

Authors: Chen HC Mueller N Stott K et al.

Source: EMBO molecular medicine [EMBO Mol Med] 2024 Nov; Vol. 16 (11), pp. 3026.

Publication Type: Published Erratum

Journal Info: Publisher: EMBO Press Country of Publication: Germany NLM ID: 101487380 Publication Model: Print Cited Medium: Internet ISSN: 1757-4684 (Electronic) Linking ISSN: 17574676 NLM ISO Abbreviation: EMBO Mol Med Subsets: MEDLINE; PubMed not MEDLINE

MMP-cleavable linker platform for tumour-responsive homo- and heterobivalent antibody-drug conjugates.

Authors: Counsell AJ Walsh SJ Ashman N et al.

Source: Chemical science [Chem Sci] 2025 Dec 03; Vol. 17 (5), pp. 2722-2731. Date of Electronic Publication: 2025 Dec 03 (Print Publication: 2026).

Publication Type: Journal Article

Journal Info: Publisher: Royal Society of Chemistry Country of Publication: England NLM ID: 101545951 Publication Model: eCollection Cited Medium: Print ISSN: 2041-6520 (Print) Linking ISSN: 20416520 NLM ISO Abbreviation: Chem Sci Subsets: PubMed not MEDLINE

An allantoin-inducible glyoxylate utilization pathway in Pseudomonas aeruginosa.

Authors: Parkhill SL Little O Askenasy I et al.

Source: Microbiology (Reading, England) [Microbiology (Reading)] 2025 Dec; Vol. 171 (12).

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Microbiology Society Country of Publication: England NLM ID: 9430468 Publication Model: Print Cited Medium: Internet ISSN: 1465-2080 (Electronic) Linking ISSN: 13500872 NLM ISO Abbreviation: Microbiology (Reading) Subsets: MEDLINE

Towards a glutathione-cleavable azobenzene linker for antibody-drug conjugates.

Authors: Kapun M Patel R Park M et al.

Source: Chemical communications (Cambridge, England) [Chem Commun (Camb)] 2025 Nov 25; Vol. 61 (95), pp. 18902-18905. Date of Electronic Publication: 2025 Nov 25.

Publication Type: Journal Article

Journal Info: Publisher: Royal Society of Chemistry Country of Publication: England NLM ID: 9610838 Publication Model: Electronic Cited Medium: Internet ISSN: 1364-548X (Electronic) Linking ISSN: 13597345 NLM ISO Abbreviation: Chem Commun (Camb) Subsets: MEDLINE

Recent progress towards catalytic asymmetric construction of inherently chiral scaffolds.

Authors: Zhu K Spring DR Shi BF et al.

Source: Chemical Society reviews [Chem Soc Rev] 2025 Nov 24; Vol. 54 (23), pp. 10856-10879. Date of Electronic Publication: 2025 Nov 24.

Publication Type: Journal Article; Review

Journal Info: Publisher: Chemical Society Country of Publication: England NLM ID: 0335405 Publication Model: Electronic Cited Medium: Internet ISSN: 1460-4744 (Electronic) Linking ISSN: 03060012 NLM ISO Abbreviation: Chem Soc Rev Subsets: MEDLINE; PubMed not MEDLINE

Novel immunotherapeutics against LGR5 to target multiple cancer types.

Authors: Chen HC Mueller N Stott K et al.

Source: EMBO molecular medicine [EMBO Mol Med] 2024 Sep; Vol. 16 (9), pp. 2233-2261. Date of Electronic Publication: 2024 Aug 21.

Publication Type: Journal Article

Journal Info: Publisher: EMBO Press Country of Publication: Germany NLM ID: 101487380 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1757-4684 (Electronic) Linking ISSN: 17574676 NLM ISO Abbreviation: EMBO Mol Med Subsets: MEDLINE

Towards the Targeted Protein Degradation of PRMT1.

Authors: Martin PL Pérez-Areales FJ Rao SV et al.

Source: ChemMedChem [ChemMedChem] 2024 Aug 19; Vol. 19 (16), pp. e202400269. Date of Electronic Publication: 2024 Jun 20.

Publication Type: Journal Article

Journal Info: Publisher: Wiley-VCH Country of Publication: Germany NLM ID: 101259013 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1860-7187 (Electronic) Linking ISSN: 18607179 NLM ISO Abbreviation: ChemMedChem Subsets: MEDLINE

Reusable tutorials for using cloud-based computing environments for the analysis of bacterial gene expression data from bulk RNA sequencing.

Authors: Allers S O'Connell KA Carlson T et al.

Source: Briefings in bioinformatics [Brief Bioinform] 2024 May 23; Vol. 25 (4).

Publication Type: Journal Article

Journal Info: Publisher: Oxford University Press Country of Publication: England NLM ID: 100912837 Publication Model: Print Cited Medium: Internet ISSN: 1477-4054 (Electronic) Linking ISSN: 14675463 NLM ISO Abbreviation: Brief Bioinform Subsets: MEDLINE

Exploiting the Cryptic αD Pocket of Casein Kinase 2α (CK2α) to Deliver Highly Potent and Selective Type 1 Inhibitors.

Authors: Glossop PA Brear P Wright S et al.

Source: Journal of medicinal chemistry [J Med Chem] 2025 Oct 23; Vol. 68 (20), pp. 21587-21614. Date of Electronic Publication: 2025 Oct 14.

Publication Type: Journal Article

Journal Info: Publisher: American Chemical Society Country of Publication: United States NLM ID: 9716531 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1520-4804 (Electronic) Linking ISSN: 00222623 NLM ISO Abbreviation: J Med Chem Subsets: MEDLINE