Search Results - "Stability"

The stability landscape of mRNA vaccines: challenges and mitigation strategies.

Authors: Zhong L Tao L Zhai Z et al.

Source: Vaccine [Vaccine] 2026 Apr 19; Vol. 79, pp. 128515. Date of Electronic Publication: 2026 Mar 24.

Publication Type: Journal Article; Review

Journal Info: Publisher: Elsevier Science Country of Publication: Netherlands NLM ID: 8406899 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-2518 (Electronic) Linking ISSN: 0264410X NLM ISO Abbreviation: Vaccine Subsets: MEDLINE

Lipopolysaccharide induces HIF-1α accumulation via MAPK p38-mediated mRNA stabilization and dexamethasone-sensitive protein stabilization.

Authors: Lockwood C Daley KK O'Neil JD et al.

Source: The Journal of biological chemistry [J Biol Chem] 2026 Feb; Vol. 302 (2), pp. 111094. Date of Electronic Publication: 2025 Dec 23.

Publication Type: Journal Article

Journal Info: Publisher: Elsevier Inc. on behalf of American Society for Biochemistry and Molecular Biology Country of Publication: United States NLM ID: 2985121R Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1083-351X (Electronic) Linking ISSN: 00219258 NLM ISO Abbreviation: J Biol Chem Subsets: MEDLINE

Post-transcriptional regulation of mRNA stability in pancreatic ductal adenocarcinoma.

Authors: Wang H Liu P Yamasaki J et al.

Source: Frontiers in immunology [Front Immunol] 2026 Jun 03; Vol. 17, pp. 1861092. Date of Electronic Publication: 2026 Jun 03 (Print Publication: 2026).

Publication Type: Journal Article; Review

Journal Info: Publisher: Frontiers Research Foundation] Country of Publication: Switzerland NLM ID: 101560960 Publication Model: eCollection Cited Medium: Internet ISSN: 1664-3224 (Electronic) Linking ISSN: 16643224 NLM ISO Abbreviation: Front Immunol Subsets: MEDLINE

Global stabilization of the transcriptome in mitotic cells.

Authors: Khalizeva E Latifkar A Xiang K et al.

Source: The EMBO journal [EMBO J] 2026 May; Vol. 45 (10), pp. 3563-3588. Date of Electronic Publication: 2026 Apr 09.

Publication Type: Journal Article

Journal Info: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 8208664 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1460-2075 (Electronic) Linking ISSN: 02614189 NLM ISO Abbreviation: EMBO J Subsets: MEDLINE

AKAP1 enhances glycogen accumulation and hepatocarcinogenesis through YTHDF2-mediated G6PC mRNA decay.

Authors: Yang T Zhang J Zhao Z et al.

Source: Signal transduction and targeted therapy [Signal Transduct Target Ther] 2026 Jun 16; Vol. 11 (1). Date of Electronic Publication: 2026 Jun 16.

Publication Type: Journal Article

Journal Info: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101676423 Publication Model: Electronic Cited Medium: Internet ISSN: 2059-3635 (Electronic) Linking ISSN: 20593635 NLM ISO Abbreviation: Signal Transduct Target Ther Subsets: MEDLINE

Inhibition of YTHDF2-mediated CYLD mRNA degradation promotes neuronal ferroptosis and pain in Parkinson's disease through NOX4 deubiquitination.

Authors: Wang F Bai S Pan Y et al.

Source: Cell biology and toxicology [Cell Biol Toxicol] 2026 Jun 06; Vol. 42 (1). Date of Electronic Publication: 2026 Jun 06.

Publication Type: Journal Article

Journal Info: Publisher: Springer Country of Publication: Switzerland NLM ID: 8506639 Publication Model: Electronic Cited Medium: Internet ISSN: 1573-6822 (Electronic) Linking ISSN: 07422091 NLM ISO Abbreviation: Cell Biol Toxicol Subsets: MEDLINE

Data-driven model reveals increased stability of CAG-expanded huntingtin RNA due to MID1 binding.

Authors: Liu Y Reisbitzer A Dorešić D et al.

Source: PLoS computational biology [PLoS Comput Biol] 2026 Jun 02; Vol. 22 (6), pp. e1014342. Date of Electronic Publication: 2026 Jun 02 (Print Publication: 2026).

Publication Type: Journal Article

Journal Info: Publisher: Public Library of Science Country of Publication: United States NLM ID: 101238922 Publication Model: eCollection Cited Medium: Internet ISSN: 1553-7358 (Electronic) Linking ISSN: 1553734X NLM ISO Abbreviation: PLoS Comput Biol Subsets: MEDLINE

Tristetraprolin attenuates schistosomiasis-induced liver fibrosis through m⁶A-mediated regulation of TGF-β1 mRNA stability.

Authors: Zhao X Wang X Liu K et al.

Source: PLoS pathogens [PLoS Pathog] 2026 May 13; Vol. 22 (5), pp. e1014007. Date of Electronic Publication: 2026 May 13 (Print Publication: 2026).

Publication Type: Journal Article

Journal Info: Publisher: Public Library of Science Country of Publication: United States NLM ID: 101238921 Publication Model: eCollection Cited Medium: Internet ISSN: 1553-7374 (Electronic) Linking ISSN: 15537366 NLM ISO Abbreviation: PLoS Pathog Subsets: MEDLINE

Human DHX29 detects nonoptimal codon usage to regulate mRNA stability.

Authors: Hia F Wu Y Yoshinaga M et al.

Source: Science (New York, N.Y.) [Science] 2026 May 07; Vol. 392 (6798), pp. eadw0288. Date of Electronic Publication: 2026 May 07.

Publication Type: Journal Article

Journal Info: Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 0404511 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1095-9203 (Electronic) Linking ISSN: 00368075 NLM ISO Abbreviation: Science Subsets: MEDLINE

TARDBP Mediates the MAP3K11/SLC3A2/GPX4 Axis in Alzheimer's Disease Rats by Enhancing KRAS mRNA Stability.

Authors: Zhao Q Yu Y Wang F et al.

Source: Journal of cellular and molecular medicine [J Cell Mol Med] 2026 May; Vol. 30 (10), pp. e71181.

Publication Type: Journal Article

Journal Info: Publisher: Wiley-Blackwell Country of Publication: England NLM ID: 101083777 Publication Model: Print Cited Medium: Internet ISSN: 1582-4934 (Electronic) Linking ISSN: 15821838 NLM ISO Abbreviation: J Cell Mol Med Subsets: MEDLINE

Applying cross-correlation for thermal stability analysis of protein therapeutics.

Authors: Knutson N Richardson J Zhang Z et al.

Source: Journal of pharmaceutical and biomedical analysis [J Pharm Biomed Anal] 2026 Jan 01; Vol. 267, pp. 117171. Date of Electronic Publication: 2025 Sep 27.

Publication Type: Journal Article

Journal Info: Publisher: Elsevier Science Country of Publication: England NLM ID: 8309336 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-264X (Electronic) Linking ISSN: 07317085 NLM ISO Abbreviation: J Pharm Biomed Anal Subsets: MEDLINE

The Role of Phase Separation and Local Mobility in the Stabilization of a Lyophilized IgG2 Formulation.

Authors: Lay-Fortenbery A Holcomb RE Henry CS et al.

Source: AAPS PharmSciTech [AAPS PharmSciTech] 2024 Nov 19; Vol. 25 (8), pp. 268. Date of Electronic Publication: 2024 Nov 19.

Publication Type: Journal Article

Journal Info: Publisher: Springer Country of Publication: United States NLM ID: 100960111 Publication Model: Electronic Cited Medium: Internet ISSN: 1530-9932 (Electronic) Linking ISSN: 15309932 NLM ISO Abbreviation: AAPS PharmSciTech Subsets: MEDLINE

Alternative buffer systems in biopharmaceutical formulations and their effect on protein stability.

Authors: Lebar B Zidar M Mravljak J et al.

Source: Acta pharmaceutica (Zagreb, Croatia) [Acta Pharm] 2024 Sep 14; Vol. 74 (3), pp. 479-493. Date of Electronic Publication: 2024 Sep 14 (Print Publication: 2024).

Publication Type: Journal Article

Journal Info: Publisher: Sciendo Country of Publication: Poland NLM ID: 9303678 Publication Model: Electronic-Print Cited Medium: Internet ISSN: 1846-9558 (Electronic) Linking ISSN: 13300075 NLM ISO Abbreviation: Acta Pharm Subsets: MEDLINE

TDP-43 directly inhibits mRNA accumulation in neurites through modulation of mRNA stability.

Authors: Moffatt C Arora A Vaeth KF et al.

Source: The EMBO journal [EMBO J] 2026 Feb; Vol. 45 (3), pp. 692-721. Date of Electronic Publication: 2025 Dec 15.

Publication Type: Journal Article

Journal Info: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 8208664 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1460-2075 (Electronic) Linking ISSN: 02614189 NLM ISO Abbreviation: EMBO J Subsets: MEDLINE

Role of Charge Heterogeneity on Physical Stability of Monoclonal Antibody Biotherapeutic Products.

Authors: Gupta S Dubey A Rathore AS

Source: Pharmaceutical research [Pharm Res] 2024 Jul; Vol. 41 (7), pp. 1443-1454. Date of Electronic Publication: 2024 Jun 28.

Publication Type: Journal Article

Journal Info: Publisher: Kluwer Academic/Plenum Publishers Country of Publication: United States NLM ID: 8406521 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1573-904X (Electronic) Linking ISSN: 07248741 NLM ISO Abbreviation: Pharm Res Subsets: MEDLINE

ADAR1 and ADAR2 associate with the RNA exosome and modulate RNA stability.

Authors: Vukić D Du Q Cherian A et al.

Source: Nucleic acids research [Nucleic Acids Res] 2026 Apr 23; Vol. 54 (8).

Publication Type: Journal Article

Journal Info: Publisher: Oxford University Press Country of Publication: England NLM ID: 0411011 Publication Model: Print Cited Medium: Internet ISSN: 1362-4962 (Electronic) Linking ISSN: 03051048 NLM ISO Abbreviation: Nucleic Acids Res Subsets: MEDLINE

Pilot Assessment of RNA Stabilization Methods for Influenza A Virus in Swine Oral Fluids.

Authors: Munguía-Ramírez B Armenta-Leyva B Giménez-Lirola L et al.

Source: Pathogens (Basel, Switzerland) [Pathogens] 2026 Apr 18; Vol. 15 (4). Date of Electronic Publication: 2026 Apr 18.

Publication Type: Journal Article

Journal Info: Publisher: MDPI AG Country of Publication: Switzerland NLM ID: 101596317 Publication Model: Electronic Cited Medium: Internet ISSN: 2076-0817 (Electronic) Linking ISSN: 20760817 NLM ISO Abbreviation: Pathogens Subsets: MEDLINE

Single-oocyte full-length isoform sequencing unveils the impact of transposable elements on RNA diversity and stability.

Authors: Wang Y Wang W Liu Y et al.

Source: Nature communications [Nat Commun] 2026 Apr 07; Vol. 17 (1). Date of Electronic Publication: 2026 Apr 07.

Publication Type: Journal Article

Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE

ZAP targets aberrant mRNA transcripts encoding proteins with defective signal peptides for degradation.

Authors: Shah A Coria AR Membréno BS et al.

Source: The EMBO journal [EMBO J] 2026 Apr; Vol. 45 (8), pp. 2638-2665. Date of Electronic Publication: 2026 Mar 12.

Publication Type: Journal Article

Journal Info: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 8208664 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1460-2075 (Electronic) Linking ISSN: 02614189 NLM ISO Abbreviation: EMBO J Subsets: MEDLINE

Mycobacterium tuberculosis MutT4/RppH is an RNA pyrophosphohydrolase that forms condensate-like bodies and impacts mRNA degradation.

Authors: Cafiero JH Xiao J Lepori I et al.

Source: Nucleic acids research [Nucleic Acids Res] 2026 Feb 24; Vol. 54 (5).

Publication Type: Journal Article

Journal Info: Publisher: Oxford University Press Country of Publication: England NLM ID: 0411011 Publication Model: Print Cited Medium: Internet ISSN: 1362-4962 (Electronic) Linking ISSN: 03051048 NLM ISO Abbreviation: Nucleic Acids Res Subsets: MEDLINE