Search Results - "Strack PR"

An accessible pharmacodynamic transcriptional biomarker for notch target engagement.

Authors: Tanis KQ Podtelezhnikov AA Blackman SC et al.

Source: Clinical pharmacology and therapeutics [Clin Pharmacol Ther] 2016 Apr; Vol. 99 (4), pp. 370-80. Date of Electronic Publication: 2016 Feb 17.

Publication Type: Clinical Trial, Phase I; Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Wiley Country of Publication: United States NLM ID: 0372741 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1532-6535 (Electronic) Linking ISSN: 00099236 NLM ISO Abbreviation: Clin Pharmacol Ther Subsets: MEDLINE

Pharmacological Inhibition of O-GlcNAcase Does Not Increase Sensitivity of Glucocorticoid Receptor-Mediated Transrepression.

Authors: Stivers PJ Harmonay L Hicks A et al.

Source: PloS one [PLoS One] 2015 Dec 15; Vol. 10 (12), pp. e0145151. Date of Electronic Publication: 2015 Dec 15 (Print Publication: 2015).

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection Cited Medium: Internet ISSN: 1932-6203 (Electronic) Linking ISSN: 19326203 NLM ISO Abbreviation: PLoS One Subsets: MEDLINE

Polymerase delta-interacting protein 38 (PDIP38) modulates the stability and activity of the mitochondrial AAA+ protease CLPXP.

Authors: Strack PR Brodie EJ Zhan H et al.

Source: Communications biology [Commun Biol] 2020 Nov 06; Vol. 3 (1), pp. 646. Date of Electronic Publication: 2020 Nov 06.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Nature Publishing Group UK Country of Publication: England NLM ID: 101719179 Publication Model: Electronic Cited Medium: Internet ISSN: 2399-3642 (Electronic) Linking ISSN: 23993642 NLM ISO Abbreviation: Commun Biol Subsets: MEDLINE

Diverse functions of mitochondrial AAA+ proteins: protein activation, disaggregation, and degradation.

Authors: Truscott KN Lowth BR Strack PR et al.

Source: Biochemistry and cell biology = Biochimie et biologie cellulaire [Biochem Cell Biol] 2010 Feb; Vol. 88 (1), pp. 97-108.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Review

Journal Info: Publisher: Canadian Science Publishing Country of Publication: Canada NLM ID: 8606068 Publication Model: Print Cited Medium: Internet ISSN: 1208-6002 (Electronic) Linking ISSN: 08298211 NLM ISO Abbreviation: Biochem Cell Biol Subsets: MEDLINE

Down-regulation of the Notch pathway mediated by a gamma-secretase inhibitor induces anti-tumour effects in mouse models of T-cell leukaemia.

Authors: Tammam J Ware C Efferson C et al.

Source: British journal of pharmacology [Br J Pharmacol] 2009 Nov; Vol. 158 (5), pp. 1183-95. Date of Electronic Publication: 2009 Sep 23.

Publication Type: Journal Article

Journal Info: Publisher: Wiley Country of Publication: England NLM ID: 7502536 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-5381 (Electronic) Linking ISSN: 00071188 NLM ISO Abbreviation: Br J Pharmacol Subsets: MEDLINE

Crosstalk between PKCα and Notch-4 in endocrine-resistant breast cancer cells.

Authors: Yun J Pannuti A Espinoza I et al.

Source: Oncogenesis [Oncogenesis] 2013 Aug 05; Vol. 2, pp. e60. Date of Electronic Publication: 2013 Aug 05.

Publication Type: Journal Article

Journal Info: Publisher: Nature Pub. Group Country of Publication: United States NLM ID: 101580004 Publication Model: Electronic Cited Medium: Print ISSN: 2157-9024 (Print) Linking ISSN: 21579024 NLM ISO Abbreviation: Oncogenesis Subsets: PubMed not MEDLINE

A zinc finger nuclease assay to rapidly quantitate homologous recombination proficiency in human cell lines.

Authors: Yuan J Strack PR Toniatti C et al.

Source: Analytical biochemistry [Anal Biochem] 2013 Mar 01; Vol. 434 (1), pp. 96-8. Date of Electronic Publication: 2012 Nov 10.

Publication Type: Journal Article

Journal Info: Publisher: Elsevier Country of Publication: United States NLM ID: 0370535 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1096-0309 (Electronic) Linking ISSN: 00032697 NLM ISO Abbreviation: Anal Biochem Subsets: MEDLINE

Inhibition of Notch signaling reduces the stem-like population of breast cancer cells and prevents mammosphere formation.

Authors: Grudzien P Lo S Albain KS et al.

Source: Anticancer research [Anticancer Res] 2010 Oct; Vol. 30 (10), pp. 3853-67.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

Journal Info: Publisher: International Institute of Anticancer Research Country of Publication: Greece NLM ID: 8102988 Publication Model: Print Cited Medium: Internet ISSN: 1791-7530 (Electronic) Linking ISSN: 02507005 NLM ISO Abbreviation: Anticancer Res Subsets: MEDLINE

Inhibition of notch signaling blocks growth of glioblastoma cell lines and tumor neurospheres.

Authors: Chen J Kesari S Rooney C et al.

Source: Genes & cancer [Genes Cancer] 2010 Aug; Vol. 1 (8), pp. 822-35.

Publication Type: Journal Article

Journal Info: Publisher: Impact Journals LLC Country of Publication: United States NLM ID: 101516546 Publication Model: Print Cited Medium: Internet ISSN: 1947-6027 (Electronic) Linking ISSN: 19476019 NLM ISO Abbreviation: Genes Cancer Subsets: PubMed not MEDLINE

Downregulation of Notch pathway by a gamma-secretase inhibitor attenuates AKT/mammalian target of rapamycin signaling and glucose uptake in an ERBB2 transgenic breast cancer model.

Authors: Efferson CL Winkelmann CT Ware C et al.

Source: Cancer research [Cancer Res] 2010 Mar 15; Vol. 70 (6), pp. 2476-84. Date of Electronic Publication: 2010 Mar 02.

Publication Type: Journal Article

Journal Info: Publisher: American Association for Cancer Research Country of Publication: United States NLM ID: 2984705R Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1538-7445 (Electronic) Linking ISSN: 00085472 NLM ISO Abbreviation: Cancer Res Subsets: MEDLINE

Interconnecting molecular pathways in the pathogenesis and drug sensitivity of T-cell acute lymphoblastic leukemia.

Authors: Sanda T Li X Gutierrez A et al.

Source: Blood [Blood] 2010 Mar 04; Vol. 115 (9), pp. 1735-45. Date of Electronic Publication: 2009 Dec 09.

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Elsevier Country of Publication: United States NLM ID: 7603509 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1528-0020 (Electronic) Linking ISSN: 00064971 NLM ISO Abbreviation: Blood Subsets: MEDLINE

Inhibition of NOTCH signaling by gamma secretase inhibitor engages the RB pathway and elicits cell cycle exit in T-cell acute lymphoblastic leukemia cells.

Authors: Rao SS O'Neil J Liberator CD et al.

Source: Cancer research [Cancer Res] 2009 Apr 01; Vol. 69 (7), pp. 3060-8. Date of Electronic Publication: 2009 Mar 24.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

Journal Info: Publisher: American Association for Cancer Research Country of Publication: United States NLM ID: 2984705R Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1538-7445 (Electronic) Linking ISSN: 00085472 NLM ISO Abbreviation: Cancer Res Subsets: MEDLINE

Opposite effects of Notch-1 and Notch-2 on mesothelioma cell survival under hypoxia are exerted through the Akt pathway.

Authors: Graziani I Eliasz S De Marco MA et al.

Source: Cancer research [Cancer Res] 2008 Dec 01; Vol. 68 (23), pp. 9678-85.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

Journal Info: Publisher: American Association for Cancer Research Country of Publication: United States NLM ID: 2984705R Publication Model: Print Cited Medium: Internet ISSN: 1538-7445 (Electronic) Linking ISSN: 00085472 NLM ISO Abbreviation: Cancer Res Subsets: MEDLINE

Control of cell growth and survival by enzymes of the fatty acid synthesis pathway in HCT-116 colon cancer cells.

Authors: Zhan Y Ginanni N Tota MR et al.

Source: Clinical cancer research : an official journal of the American Association for Cancer Research [Clin Cancer Res] 2008 Sep 15; Vol. 14 (18), pp. 5735-42.

Publication Type: Journal Article

Journal Info: Publisher: American Association for Cancer Research Country of Publication: United States NLM ID: 9502500 Publication Model: Print Cited Medium: Print ISSN: 1078-0432 (Print) Linking ISSN: 10780432 NLM ISO Abbreviation: Clin Cancer Res Subsets: MEDLINE

Oxygen concentration determines the biological effects of NOTCH-1 signaling in adenocarcinoma of the lung.

Authors: Chen Y De Marco MA Graziani I et al.

Source: Cancer research [Cancer Res] 2007 Sep 01; Vol. 67 (17), pp. 7954-9.

Publication Type: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't

Journal Info: Publisher: American Association for Cancer Research Country of Publication: United States NLM ID: 2984705R Publication Model: Print Cited Medium: Print ISSN: 0008-5472 (Print) Linking ISSN: 00085472 NLM ISO Abbreviation: Cancer Res Subsets: MEDLINE

Apoptosis in T cell acute lymphoblastic leukemia cells after cell cycle arrest induced by pharmacological inhibition of notch signaling.

Authors: Lewis HD Leveridge M Strack PR et al.

Source: Chemistry & biology [Chem Biol] 2007 Feb; Vol. 14 (2), pp. 209-19.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Elsevier Country of Publication: United States NLM ID: 9500160 Publication Model: Print Cited Medium: Print ISSN: 1074-5521 (Print) Linking ISSN: 10745521 NLM ISO Abbreviation: Chem Biol Subsets: MEDLINE

3-Aryl-4-hydroxyquinolin-2(1H)-one derivatives as type I fatty acid synthase inhibitors.

Authors: Rivkin A Kim YR Goulet MT et al.

Source: Bioorganic & medicinal chemistry letters [Bioorg Med Chem Lett] 2006 Sep 01; Vol. 16 (17), pp. 4620-3. Date of Electronic Publication: 2006 Jun 19.

Publication Type: Journal Article

Journal Info: Publisher: Elsevier Science Ltd Country of Publication: England NLM ID: 9107377 Publication Model: Print-Electronic Cited Medium: Print ISSN: 0960-894X (Print) Linking ISSN: 0960894X NLM ISO Abbreviation: Bioorg Med Chem Lett Subsets: MEDLINE

Apoptosis mediated by HIV protease is preceded by cleavage of Bcl-2.

Authors: Strack PR Frey MW Rizzo CJ et al.

Source: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 1996 Sep 03; Vol. 93 (18), pp. 9571-6.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

Journal Info: Publisher: National Academy of Sciences Country of Publication: United States NLM ID: 7505876 Publication Model: Print Cited Medium: Print ISSN: 0027-8424 (Print) Linking ISSN: 00278424 NLM ISO Abbreviation: Proc Natl Acad Sci U S A Subsets: MEDLINE

Activation of the multicatalytic endopeptidase by oxidants. Effects on enzyme structure.

Authors: Strack PR Waxman L Fagan JM

Source: Biochemistry [Biochemistry] 1996 Jun 04; Vol. 35 (22), pp. 7142-9.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, U.S. Gov't, P.H.S.

Journal Info: Publisher: American Chemical Society Country of Publication: United States NLM ID: 0370623 Publication Model: Print Cited Medium: Print ISSN: 0006-2960 (Print) Linking ISSN: 00062960 NLM ISO Abbreviation: Biochemistry Subsets: MEDLINE

ATP-stimulated degradation of oxidatively modified superoxide dismutase by cathepsin D in cardiac tissue extracts.

Authors: Strack PR Waxman L Fagan JM

Source: Biochemical and biophysical research communications [Biochem Biophys Res Commun] 1996 Feb 15; Vol. 219 (2), pp. 348-53.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, U.S. Gov't, P.H.S.

Journal Info: Publisher: Elsevier Country of Publication: United States NLM ID: 0372516 Publication Model: Print Cited Medium: Print ISSN: 0006-291X (Print) Linking ISSN: 0006291X NLM ISO Abbreviation: Biochem Biophys Res Commun Subsets: MEDLINE