Search Results - "Stratton, Christopher F."

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A diversity-oriented synthesis approach to macrocycles via oxidative ring expansion.

Authors: Kopp, Felix Stratton, Christopher F Akella, Lakshmi B et al.

Source: Nature Chemical Biology. Apr2012, Vol. 8 Issue 4, p358-365. 8p. 3 Diagrams, 3 Charts, 1 Graph.

Evidence from Raman Spectroscopy That InhA, the Mycobacterial Enoyl Reductase, Modulates the Conformation of the NADH Cofactor to Promote Catalysis.

Authors: Bell, Alasdair F. Stratton, Christopher F. Xujie Zhang et al.

Source: Journal of the American Chemical Society. 5/23/2007, Vol. 129 Issue 20, p6425-6431. 7p.

Subjects: Raman spectroscopy, Size reduction of materials, Raman effect, Nanoparticles, Physical & theoretical chemistry, Chemistry

Cheminformatic comparison of approved drugs from natural product versus synthetic origins.

Authors: Stratton, Christopher F. Newman, David J. Tan, Derek S.

Source: Bioorganic & Medicinal Chemistry Letters. Nov2015, Vol. 25 Issue 21, p4802-4807. 6p.

Mechanism and Inhibition of saFabl, the Enoyl Reductase from Staphylococcus aureus.

Authors: Hua Xu Sullivan, Todd J. Sekiguchi, Jun-ichiro et al.

Source: Biochemistry. 4/8/2008, Vol. 47 Issue 14, p4228-4236. 9p. 3 Diagrams, 5 Charts, 1 Graph.

Structure of Acyl Carrier Protein Bound to Fabl, the FASII Enoyl Reductase from Escherichia coli.

Authors: Rafi, Salma Novichenok, Polina Kolappan, Subramaniapillai et al.

Source: Journal of Biological Chemistry. 12/22/2006, Vol. 281 Issue 51, p39285-39293. 9p. 4 Diagrams, 2 Charts, 1 Graph.

Optimization of Covalent 6-Cyanoquinazoline KRAS^G12C Inhibitors for the Treatment of Solid Tumors.

Authors: Waldo JP Krawczuk PJ Kelly CB et al.

Source: Journal of medicinal chemistry [J Med Chem] 2026 Apr 23; Vol. 69 (8), pp. 9163-9195. Date of Electronic Publication: 2026 Apr 01.

Publication Type: Journal Article

Journal Info: Publisher: American Chemical Society Country of Publication: United States NLM ID: 9716531 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1520-4804 (Electronic) Linking ISSN: 00222623 NLM ISO Abbreviation: J Med Chem Subsets: MEDLINE

Discovery of Potent and Orally Bioavailable Pyridine N-Oxide-Based Factor XIa Inhibitors through Exploiting Nonclassical Interactions.

Authors: Xu G Liu Z Wang X et al.

Source: Journal of medicinal chemistry [J Med Chem] 2022 Aug 11; Vol. 65 (15), pp. 10419-10440. Date of Electronic Publication: 2022 Jul 21.

Publication Type: Journal Article; Research Support, U.S. Gov't, Non-P.H.S.

Journal Info: Publisher: American Chemical Society Country of Publication: United States NLM ID: 9716531 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1520-4804 (Electronic) Linking ISSN: 00222623 NLM ISO Abbreviation: J Med Chem Subsets: MEDLINE

Niraparib Shows Superior Tissue Distribution and Efficacy in a Prostate Cancer Bone Metastasis Model Compared with Other PARP Inhibitors.

Authors: Snyder LA Damle R Patel S et al.

Source: Molecular cancer therapeutics [Mol Cancer Ther] 2022 Jul 05; Vol. 21 (7), pp. 1115-1124.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

Journal Info: Publisher: American Association for Cancer Research, Inc Country of Publication: United States NLM ID: 101132535 Publication Model: Print Cited Medium: Internet ISSN: 1538-8514 (Electronic) Linking ISSN: 15357163 NLM ISO Abbreviation: Mol Cancer Ther Subsets: MEDLINE

Kinetic Isotope Effects and Transition State Structure for Human Phenylethanolamine N-Methyltransferase.

Authors: Stratton CF Poulin MB Du Q et al.

Source: ACS chemical biology [ACS Chem Biol] 2017 Feb 17; Vol. 12 (2), pp. 342-346. Date of Electronic Publication: 2016 Dec 28.

Publication Type: Journal Article; Research Support, N.I.H., Extramural

Journal Info: Publisher: American Chemical Society Country of Publication: United States NLM ID: 101282906 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1554-8937 (Electronic) Linking ISSN: 15548929 NLM ISO Abbreviation: ACS Chem Biol Subsets: MEDLINE

Binding Isotope Effects for Interrogating Enzyme-Substrate Interactions.

Authors: Stratton CF Poulin MB Schramm VL

Source: Methods in enzymology [Methods Enzymol] 2017; Vol. 596, pp. 1-21. Date of Electronic Publication: 2017 Aug 31.

Publication Type: Journal Article

Journal Info: Publisher: Academic Press Country of Publication: United States NLM ID: 0212271 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1557-7988 (Electronic) Linking ISSN: 00766879 NLM ISO Abbreviation: Methods Enzymol Subsets: MEDLINE

Transition State Structure and Inhibition of Rv0091, a 5'-Deoxyadenosine/5'-methylthioadenosine Nucleosidase from Mycobacterium tuberculosis.

Authors: Namanja-Magliano HA Stratton CF Schramm VL

Source: ACS chemical biology [ACS Chem Biol] 2016 Jun 17; Vol. 11 (6), pp. 1669-76. Date of Electronic Publication: 2016 Apr 08.

Publication Type: Journal Article; Research Support, N.I.H., Extramural

Journal Info: Publisher: American Chemical Society Country of Publication: United States NLM ID: 101282906 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1554-8937 (Electronic) Linking ISSN: 15548929 NLM ISO Abbreviation: ACS Chem Biol Subsets: MEDLINE

Transition State Structure of RNA Depurination by Saporin L3.

Authors: Yuan H Stratton CF Schramm VL

Source: ACS chemical biology [ACS Chem Biol] 2016 May 20; Vol. 11 (5), pp. 1383-90. Date of Electronic Publication: 2016 Mar 08.

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

Journal Info: Publisher: American Chemical Society Country of Publication: United States NLM ID: 101282906 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1554-8937 (Electronic) Linking ISSN: 15548929 NLM ISO Abbreviation: ACS Chem Biol Subsets: MEDLINE

Binding Isotope Effects for para-Aminobenzoic Acid with Dihydropteroate Synthase from Staphylococcus aureus and Plasmodium falciparum.

Authors: Stratton CF Namanja-Magliano HA Cameron SA et al.

Source: ACS chemical biology [ACS Chem Biol] 2015 Oct 16; Vol. 10 (10), pp. 2182-6. Date of Electronic Publication: 2015 Aug 27.

Publication Type: Comparative Study; Letter; Research Support, N.I.H., Extramural

Journal Info: Publisher: American Chemical Society Country of Publication: United States NLM ID: 101282906 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1554-8937 (Electronic) Linking ISSN: 15548929 NLM ISO Abbreviation: ACS Chem Biol Subsets: MEDLINE

Principal component analysis as a tool for library design: a case study investigating natural products, brand-name drugs, natural product-like libraries, and drug-like libraries.

Authors: Wenderski TA Stratton CF Bauer RA et al.

Source: Methods in molecular biology (Clifton, N.J.) [Methods Mol Biol] 2015; Vol. 1263, pp. 225-42.

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Humana Press Country of Publication: United States NLM ID: 9214969 Publication Model: Print Cited Medium: Internet ISSN: 1940-6029 (Electronic) Linking ISSN: 10643745 NLM ISO Abbreviation: Methods Mol Biol Subsets: MEDLINE

Immucillin-H, a purine nucleoside phosphorylase transition state analog, causes non-lethal attenuation of growth in Staphylococcus aureus.

Authors: Stratton CF Schramm VL

Source: Bioinformation [Bioinformation] 2013; Vol. 9 (1), pp. 9-17. Date of Electronic Publication: 2013 Jan 09.

Publication Type: Journal Article

Journal Info: Publisher: Biomedical Informatics Pub. Group Country of Publication: Singapore NLM ID: 101258255 Publication Model: Print-Electronic Cited Medium: Print ISSN: 0973-2063 (Print) Linking ISSN: 09732063 NLM ISO Abbreviation: Bioinformation Subsets: PubMed not MEDLINE

High affinity InhA inhibitors with activity against drug-resistant strains of Mycobacterium tuberculosis.

Authors: Sullivan TJ Truglio JJ Boyne ME et al.

Source: ACS chemical biology [ACS Chem Biol] 2006 Feb 17; Vol. 1 (1), pp. 43-53.

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

Journal Info: Publisher: American Chemical Society Country of Publication: United States NLM ID: 101282906 Publication Model: Print Cited Medium: Internet ISSN: 1554-8937 (Electronic) Linking ISSN: 15548929 NLM ISO Abbreviation: ACS Chem Biol Subsets: MEDLINE