Search Results - "Stratton CF"

Optimization of Covalent 6-Cyanoquinazoline KRAS^G12C Inhibitors for the Treatment of Solid Tumors.

Authors: Waldo JP Krawczuk PJ Kelly CB et al.

Source: Journal of medicinal chemistry [J Med Chem] 2026 Apr 23; Vol. 69 (8), pp. 9163-9195. Date of Electronic Publication: 2026 Apr 01.

Publication Type: Journal Article

Journal Info: Publisher: American Chemical Society Country of Publication: United States NLM ID: 9716531 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1520-4804 (Electronic) Linking ISSN: 00222623 NLM ISO Abbreviation: J Med Chem Subsets: MEDLINE

Human genetics guides the discovery of CARD9 inhibitors with anti-inflammatory activity.

Authors: Rush JS Wertheimer JD Goldberg SD et al.

Source: Cell [Cell] 2026 Mar 05; Vol. 189 (5), pp. 1356-1370.e26. Date of Electronic Publication: 2026 Jan 16.

Publication Type: Journal Article

Journal Info: Publisher: Cell Press Country of Publication: United States NLM ID: 0413066 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1097-4172 (Electronic) Linking ISSN: 00928674 NLM ISO Abbreviation: Cell Subsets: MEDLINE

Discovery of Potent and Orally Bioavailable Pyridine N-Oxide-Based Factor XIa Inhibitors through Exploiting Nonclassical Interactions.

Authors: Xu G Liu Z Wang X et al.

Source: Journal of medicinal chemistry [J Med Chem] 2022 Aug 11; Vol. 65 (15), pp. 10419-10440. Date of Electronic Publication: 2022 Jul 21.

Publication Type: Journal Article; Research Support, U.S. Gov't, Non-P.H.S.

Journal Info: Publisher: American Chemical Society Country of Publication: United States NLM ID: 9716531 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1520-4804 (Electronic) Linking ISSN: 00222623 NLM ISO Abbreviation: J Med Chem Subsets: MEDLINE

Niraparib Shows Superior Tissue Distribution and Efficacy in a Prostate Cancer Bone Metastasis Model Compared with Other PARP Inhibitors.

Authors: Snyder LA Damle R Patel S et al.

Source: Molecular cancer therapeutics [Mol Cancer Ther] 2022 Jul 05; Vol. 21 (7), pp. 1115-1124.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

Journal Info: Publisher: American Association for Cancer Research, Inc Country of Publication: United States NLM ID: 101132535 Publication Model: Print Cited Medium: Internet ISSN: 1538-8514 (Electronic) Linking ISSN: 15357163 NLM ISO Abbreviation: Mol Cancer Ther Subsets: MEDLINE

A diversity-oriented synthesis approach to macrocycles via oxidative ring expansion.

Authors: Kopp F Stratton CF Akella LB et al.

Source: Nature chemical biology [Nat Chem Biol] 2012 Mar 11; Vol. 8 (4), pp. 358-65. Date of Electronic Publication: 2012 Mar 11.

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Nature Pub. Group Country of Publication: United States NLM ID: 101231976 Publication Model: Electronic Cited Medium: Internet ISSN: 1552-4469 (Electronic) Linking ISSN: 15524450 NLM ISO Abbreviation: Nat Chem Biol Subsets: MEDLINE

Kinetic Isotope Effects and Transition State Structure for Human Phenylethanolamine N-Methyltransferase.

Authors: Stratton CF Poulin MB Du Q et al.

Source: ACS chemical biology [ACS Chem Biol] 2017 Feb 17; Vol. 12 (2), pp. 342-346. Date of Electronic Publication: 2016 Dec 28.

Publication Type: Journal Article; Research Support, N.I.H., Extramural

Journal Info: Publisher: American Chemical Society Country of Publication: United States NLM ID: 101282906 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1554-8937 (Electronic) Linking ISSN: 15548929 NLM ISO Abbreviation: ACS Chem Biol Subsets: MEDLINE

Binding Isotope Effects for Interrogating Enzyme-Substrate Interactions.

Authors: Stratton CF Poulin MB Schramm VL

Source: Methods in enzymology [Methods Enzymol] 2017; Vol. 596, pp. 1-21. Date of Electronic Publication: 2017 Aug 31.

Publication Type: Journal Article

Journal Info: Publisher: Academic Press Country of Publication: United States NLM ID: 0212271 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1557-7988 (Electronic) Linking ISSN: 00766879 NLM ISO Abbreviation: Methods Enzymol Subsets: MEDLINE

Transition State Structure and Inhibition of Rv0091, a 5'-Deoxyadenosine/5'-methylthioadenosine Nucleosidase from Mycobacterium tuberculosis.

Authors: Namanja-Magliano HA Stratton CF Schramm VL

Source: ACS chemical biology [ACS Chem Biol] 2016 Jun 17; Vol. 11 (6), pp. 1669-76. Date of Electronic Publication: 2016 Apr 08.

Publication Type: Journal Article; Research Support, N.I.H., Extramural

Journal Info: Publisher: American Chemical Society Country of Publication: United States NLM ID: 101282906 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1554-8937 (Electronic) Linking ISSN: 15548929 NLM ISO Abbreviation: ACS Chem Biol Subsets: MEDLINE

Transition State Structure of RNA Depurination by Saporin L3.

Authors: Yuan H Stratton CF Schramm VL

Source: ACS chemical biology [ACS Chem Biol] 2016 May 20; Vol. 11 (5), pp. 1383-90. Date of Electronic Publication: 2016 Mar 08.

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

Journal Info: Publisher: American Chemical Society Country of Publication: United States NLM ID: 101282906 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1554-8937 (Electronic) Linking ISSN: 15548929 NLM ISO Abbreviation: ACS Chem Biol Subsets: MEDLINE

Cheminformatic comparison of approved drugs from natural product versus synthetic origins.

Authors: Stratton CF Newman DJ Tan DS

Source: Bioorganic & medicinal chemistry letters [Bioorg Med Chem Lett] 2015 Nov 01; Vol. 25 (21), pp. 4802-4807. Date of Electronic Publication: 2015 Jul 14.

Publication Type: Comparative Study; Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Elsevier Science Ltd Country of Publication: England NLM ID: 9107377 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1464-3405 (Electronic) Linking ISSN: 0960894X NLM ISO Abbreviation: Bioorg Med Chem Lett Subsets: MEDLINE

Binding Isotope Effects for para-Aminobenzoic Acid with Dihydropteroate Synthase from Staphylococcus aureus and Plasmodium falciparum.

Authors: Stratton CF Namanja-Magliano HA Cameron SA et al.

Source: ACS chemical biology [ACS Chem Biol] 2015 Oct 16; Vol. 10 (10), pp. 2182-6. Date of Electronic Publication: 2015 Aug 27.

Publication Type: Comparative Study; Letter; Research Support, N.I.H., Extramural

Journal Info: Publisher: American Chemical Society Country of Publication: United States NLM ID: 101282906 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1554-8937 (Electronic) Linking ISSN: 15548929 NLM ISO Abbreviation: ACS Chem Biol Subsets: MEDLINE

Principal component analysis as a tool for library design: a case study investigating natural products, brand-name drugs, natural product-like libraries, and drug-like libraries.

Authors: Wenderski TA Stratton CF Bauer RA et al.

Source: Methods in molecular biology (Clifton, N.J.) [Methods Mol Biol] 2015; Vol. 1263, pp. 225-42.

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Humana Press Country of Publication: United States NLM ID: 9214969 Publication Model: Print Cited Medium: Internet ISSN: 1940-6029 (Electronic) Linking ISSN: 10643745 NLM ISO Abbreviation: Methods Mol Biol Subsets: MEDLINE

Immucillin-H, a purine nucleoside phosphorylase transition state analog, causes non-lethal attenuation of growth in Staphylococcus aureus.

Authors: Stratton CF Schramm VL

Source: Bioinformation [Bioinformation] 2013; Vol. 9 (1), pp. 9-17. Date of Electronic Publication: 2013 Jan 09.

Publication Type: Journal Article

Journal Info: Publisher: Biomedical Informatics Pub. Group Country of Publication: Singapore NLM ID: 101258255 Publication Model: Print-Electronic Cited Medium: Print ISSN: 0973-2063 (Print) Linking ISSN: 09732063 NLM ISO Abbreviation: Bioinformation Subsets: PubMed not MEDLINE

Mechanism and inhibition of saFabI, the enoyl reductase from Staphylococcus aureus.

Authors: Xu H Sullivan TJ Sekiguchi J et al.

Source: Biochemistry [Biochemistry] 2008 Apr 08; Vol. 47 (14), pp. 4228-36. Date of Electronic Publication: 2008 Mar 13.

Publication Type: Journal Article; Research Support, N.I.H., Extramural

Journal Info: Publisher: American Chemical Society Country of Publication: United States NLM ID: 0370623 Publication Model: Print-Electronic Cited Medium: Print ISSN: 0006-2960 (Print) Linking ISSN: 00062960 NLM ISO Abbreviation: Biochemistry Subsets: MEDLINE

Evidence from Raman spectroscopy that InhA, the mycobacterial enoyl reductase, modulates the conformation of the NADH cofactor to promote catalysis.

Authors: Bell AF Stratton CF Zhang X et al.

Source: Journal of the American Chemical Society [J Am Chem Soc] 2007 May 23; Vol. 129 (20), pp. 6425-31. Date of Electronic Publication: 2007 May 02.

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.

Journal Info: Publisher: American Chemical Society Country of Publication: United States NLM ID: 7503056 Publication Model: Print-Electronic Cited Medium: Print ISSN: 0002-7863 (Print) Linking ISSN: 00027863 NLM ISO Abbreviation: J Am Chem Soc Subsets: MEDLINE

Structure of acyl carrier protein bound to FabI, the FASII enoyl reductase from Escherichia coli.

Authors: Rafi S Novichenok P Kolappan S et al.

Source: The Journal of biological chemistry [J Biol Chem] 2006 Dec 22; Vol. 281 (51), pp. 39285-39293. Date of Electronic Publication: 2006 Sep 29.

Publication Type: Journal Article; Research Support, N.I.H., Extramural

Journal Info: Publisher: Elsevier Inc. on behalf of American Society for Biochemistry and Molecular Biology Country of Publication: United States NLM ID: 2985121R Publication Model: Print-Electronic Cited Medium: Print ISSN: 0021-9258 (Print) Linking ISSN: 00219258 NLM ISO Abbreviation: J Biol Chem Subsets: MEDLINE

High affinity InhA inhibitors with activity against drug-resistant strains of Mycobacterium tuberculosis.

Authors: Sullivan TJ Truglio JJ Boyne ME et al.

Source: ACS chemical biology [ACS Chem Biol] 2006 Feb 17; Vol. 1 (1), pp. 43-53.

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

Journal Info: Publisher: American Chemical Society Country of Publication: United States NLM ID: 101282906 Publication Model: Print Cited Medium: Internet ISSN: 1554-8937 (Electronic) Linking ISSN: 15548929 NLM ISO Abbreviation: ACS Chem Biol Subsets: MEDLINE