Search Results - "Struthers RS"

Immune signatures of SARS-CoV-2 infection resolution in human lung tissues.

Authors: Kenney, Devin O'Connell, Aoife K. Tseng, Anna E. et al.

Source: PLoS Pathogens. 9/8/2025, Vol. 21 Issue 9, p1-28. 28p.

Discovery of CRN04894: A Novel Potent Selective MC2R Antagonist.

Authors: Kim SH Han S Zhao J et al.

Source: ACS medicinal chemistry letters [ACS Med Chem Lett] 2024 Mar 19; Vol. 15 (4), pp. 478-485. Date of Electronic Publication: 2024 Mar 19 (Print Publication: 2024).

Publication Type: Journal Article

Journal Info: Publisher: American Chemical Society Country of Publication: United States NLM ID: 101521073 Publication Model: eCollection Cited Medium: Print ISSN: 1948-5875 (Print) Linking ISSN: 19485875 NLM ISO Abbreviation: ACS Med Chem Lett Subsets: PubMed not MEDLINE

Discovery of Paltusotine (CRN00808), a Potent, Selective, and Orally Bioavailable Non-peptide SST2 Agonist.

Authors: Zhao J Wang S Markison S et al.

Source: ACS medicinal chemistry letters [ACS Med Chem Lett] 2022 Dec 10; Vol. 14 (1), pp. 66-74. Date of Electronic Publication: 2022 Dec 10 (Print Publication: 2023).

Publication Type: Journal Article

Journal Info: Publisher: American Chemical Society Country of Publication: United States NLM ID: 101521073 Publication Model: eCollection Cited Medium: Print ISSN: 1948-5875 (Print) Linking ISSN: 19485875 NLM ISO Abbreviation: ACS Med Chem Lett Subsets: PubMed not MEDLINE

Computational modelling reveals novel insights into GnRH receptor activation and binding dynamics.

Authors: Paspali, Elpiniki Ferro, Valerie Anne Kubiak-Ossowska, Karina et al.

Source: Scientific Reports. 11/27/2025, Vol. 15 Issue 1, p1-15. 15p.

The Concise Guide to PHARMACOLOGY 2023/24: G protein-coupled receptors.

Authors: Alexander, Stephen P. H. Christopoulos, Arthur Davenport, Anthony P. et al.

Source: British Journal of Pharmacology. Oct2023 Supplement 1, Vol. 180 Issue 2, pS23-S144. 122p. 1 Chart.

The Significant Role of Peptide Synthesis in the Early Days of Antimicrobial Peptide Research.

Authors: Andreu, David¹ (AUTHOR) david.andreu@upf.edu

Source: International Journal of Peptide Research & Therapeutics. Mar2025, Vol. 31 Issue 2, p1-11. 11p.

Restoring function to inactivating G protein‐coupled receptor variants in the hypothalamic–pituitary–gonadal axis¹.

Authors: Radomsky, Tarryn Anderson, Ross C. Millar, Robert P. et al.

Source: Journal of Neuroendocrinology. Sep2024, Vol. 36 Issue 9, p1-20. 20p.

Unlocking the Potential of Retro-Inverso (RI) Peptides as Future Drug Candidates.

Authors: Al Musaimi, Othman^1,2 (AUTHOR) othman.almusaimi@newcastle.ac.uk

Source: International Journal of Peptide Research & Therapeutics. Sep2024, Vol. 30 Issue 5, p1-16. 16p.

Discovery of substituted 3H-pyrido[2,3-d]pyrimidin-4-ones as potent, biased, and orally bioavailable sst2 agonist.

Authors: Zhao J Chen Z Kusnetzow AK et al.

Source: Bioorganic & medicinal chemistry letters [Bioorg Med Chem Lett] 2020 Nov 01; Vol. 30 (21), pp. 127496. Date of Electronic Publication: 2020 Aug 14.

Publication Type: Journal Article; Research Support, N.I.H., Extramural

Journal Info: Publisher: Elsevier Science Ltd Country of Publication: England NLM ID: 9107377 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1464-3405 (Electronic) Linking ISSN: 0960894X NLM ISO Abbreviation: Bioorg Med Chem Lett Subsets: MEDLINE

THE CONCISE GUIDE TO PHARMACOLOGY 2021/22: G protein-coupled receptors.

Authors: Alexander, Stephen PH Christopoulos, Arthur Davenport, Anthony P et al.

Source: British Journal of Pharmacology. Oct2021 Supplement S1, Vol. 178, pS27-S156. 130p. 1 Color Photograph.

Validation of a quantitative systems pharmacology model of calcium homeostasis using elagolix Phase 3 clinical trial data in women with endometriosis.

Authors: Stodtmann, Sven Nader, Ahmed Polepally, Akshanth R. et al.

Source: CTS: Clinical & Translational Science. Jul2021, Vol. 14 Issue 4, p1611-1619. 9p.

Safety and efficacy of elagolix (with and without add-back therapy) for the treatment of heavy menstrual bleeding associated with uterine leiomyomas: a systematic review and meta-analysis.

Authors: Ali, Mustafa Hira, Aruna Kumari Jawaid, Haris et al.

Source: Middle East Fertility Society Journal. 2021, Vol. 26 Issue 1, p1-12. 12p.

Chiral discrimination of small substituents in biaryl atropisomer construction: enantioselective synthesis of axially chiral 1-azafluorene via Ni-catalyzed [2+2+2] cycloaddition.

Authors: Peng, Jin-Huang Zheng, Yu-Qing Bai, Li-Gang et al.

Source: SCIENCE CHINA Chemistry. Nov2023, Vol. 66 Issue 11, p3148-3153. 6p.

THE CONCISE GUIDE TO PHARMACOLOGY 2019/20: G protein-coupled receptors.

Authors: Alexander, Stephen PH Christopoulos, Arthur Davenport, Anthony P et al.

Source: British Journal of Pharmacology. Dec2019 Supplement S1, Vol. 176, pS21-S141. 121p. 1 Diagram, 1 Chart.

Elagolix Pharmacokinetic Profiles in Women With Renal or Hepatic Impairment.

Authors: Ng, Juki Duan, W. Rachel Marbury, Thomas et al.

Source: Clinical Pharmacology in Drug Development. Nov2019, Vol. 8 Issue 8, p1053-1061. 9p.

Molecular imaging of HER2 expression in breast cancer patients using a novel peptide-based tracer ^99mTc-HP-Ark2: a pilot study.

Authors: Shi, Jiyun Du, Shuaifan Wang, Rongxi et al.

Source: Journal of Translational Medicine. 1/11/2023, Vol. 21 Issue 1, p1-17. 17p.

Pharmacologic Interventions for Endometriosis-Related Pain: A Systematic Review and Meta-analysis.

Authors: Kou L Huang C Xiao D et al.

Source: Obstetrics and gynecology [Obstet Gynecol] 2025 May 15; Vol. 146 (2), pp. e23-e35. Date of Electronic Publication: 2025 May 15.

Publication Type: Journal Article; Systematic Review; Network Meta-Analysis

Journal Info: Publisher: Lippincott Williams & Wilkins Country of Publication: United States NLM ID: 0401101 Publication Model: Electronic Cited Medium: Internet ISSN: 1873-233X (Electronic) Linking ISSN: 00297844 NLM ISO Abbreviation: Obstet Gynecol Subsets: MEDLINE

Effects of elagolix on the pharmacokinetics of omeprazole and its metabolites in healthy premenopausal women.

Authors: Nader, Ahmed Mostafa, Nael M. Kim, Elaine et al.

Source: CTS: Clinical & Translational Science. May2022, Vol. 15 Issue 5, p1269-1280. 12p.

Spatial determinates of effector and memory CD8⁺ T cell fates*.

Authors: Duckworth, Brigette C. Qin, Raymond Z. Groom, Joanna R.

Source: Immunological Reviews. Mar2022, Vol. 306 Issue 1, p76-92. 17p.

Does CCL19 act as a double-edged sword in cancer development?

Authors: Gowhari Shabgah, Arezoo Al-Obaidi, Zaid Mahdi Jaber Sulaiman Rahman, Heshu et al.

Source: Clinical & Experimental Immunology. Feb2022, Vol. 207 Issue 2, p164-175. 12p.