Search Results - "Talele TT"

Retraction Note: Thiazole-valine peptidomimetic (TTT-28) antagonizes multidrug resistance in vitro and in vivo by selectively inhibiting the efflux activity of ABCB1.

Authors: Wang YJ Patel BA Anreddy N et al.

Source: Scientific reports [Sci Rep] 2025 Dec 30; Vol. 15 (1), pp. 45670. Date of Electronic Publication: 2025 Dec 30.

Publication Type: Journal Article; Retraction Notice

Journal Info: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN: 2045-2322 (Electronic) Linking ISSN: 20452322 NLM ISO Abbreviation: Sci Rep Subsets: MEDLINE; In Process

Structure-activity relationship studies on 2-thienylidene substituted 3-oxo-2,3-dihydrobenzofuran-7-carboxamides as poly (ADP-ribose) polymerase inhibitors.

Authors: Salami A Adiele U Coate G et al.

Source: Bioorganic chemistry [Bioorg Chem] 2025 Oct; Vol. 165, pp. 108941. Date of Electronic Publication: 2025 Sep 05.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Extramural

Journal Info: Publisher: Elsevier Country of Publication: United States NLM ID: 1303703 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1090-2120 (Electronic) Linking ISSN: 00452068 NLM ISO Abbreviation: Bioorg Chem Subsets: MEDLINE

Novel modifications of PARP inhibitor veliparib increase PARP1 binding to DNA breaks.

Authors: Velagapudi UK Rouleau-Turcotte É Billur R et al.

Source: The Biochemical journal [Biochem J] 2024 Mar 20; Vol. 481 (6), pp. 437-460.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Extramural

Journal Info: Publisher: Published by Portland Press on behalf of the Biochemical Society Country of Publication: England NLM ID: 2984726R Publication Model: Print Cited Medium: Internet ISSN: 1470-8728 (Electronic) Linking ISSN: 02646021 NLM ISO Abbreviation: Biochem J Subsets: MEDLINE

Discovery of a Novel [6-6-5-5-6] Pentacyclic Tetrahydrocyclopentaphthalazinone as a Promising PARP Inhibitor Scaffold.

Authors: Doruk YU Diolaiti ME Ashworth A et al.

Source: ACS medicinal chemistry letters [ACS Med Chem Lett] 2025 Apr 03; Vol. 16 (5), pp. 776-783. Date of Electronic Publication: 2025 Apr 03 (Print Publication: 2025).

Publication Type: Journal Article

Journal Info: Publisher: American Chemical Society Country of Publication: United States NLM ID: 101521073 Publication Model: eCollection Cited Medium: Print ISSN: 1948-5875 (Print) Linking ISSN: 19485875 NLM ISO Abbreviation: ACS Med Chem Lett Subsets: PubMed not MEDLINE

A PARP2 active site helix melts to permit DNA damage-induced enzymatic activation.

Authors: Smith-Pillet ES Billur R Langelier MF et al.

Source: Molecular cell [Mol Cell] 2025 Mar 06; Vol. 85 (5), pp. 865-876.e4. Date of Electronic Publication: 2025 Jan 30.

Publication Type: Journal Article

Journal Info: Publisher: Cell Press Country of Publication: United States NLM ID: 9802571 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1097-4164 (Electronic) Linking ISSN: 10972765 NLM ISO Abbreviation: Mol Cell Subsets: MEDLINE

Nek2 Kinase Signaling in Malaria, Bone, Immune and Kidney Disorders to Metastatic Cancers and Drug Resistance: Progress on Nek2 Inhibitor Development.

Authors: Dana D Das T Choi A et al.

Source: Molecules (Basel, Switzerland) [Molecules] 2022 Jan 06; Vol. 27 (2). Date of Electronic Publication: 2022 Jan 06.

Publication Type: Journal Article; Review

Journal Info: Publisher: MDPI Country of Publication: Switzerland NLM ID: 100964009 Publication Model: Electronic Cited Medium: Internet ISSN: 1420-3049 (Electronic) Linking ISSN: 14203049 NLM ISO Abbreviation: Molecules Subsets: MEDLINE

Correction to: 2‑O, 3‑O desulfated heparin (ODSH) increases bacterial clearance and attenuates lung injury in cystic fibrosis by restoring HMGB1‑compromised macrophage function.

Authors: Wang M Gauthier AG Kennedy TP et al.

Source: Molecular medicine (Cambridge, Mass.) [Mol Med] 2021 Sep 03; Vol. 27 (1), pp. 98. Date of Electronic Publication: 2021 Sep 03.

Publication Type: Published Erratum

Journal Info: Publisher: BioMed Central Country of Publication: England NLM ID: 9501023 Publication Model: Electronic Cited Medium: Internet ISSN: 1528-3658 (Electronic) Linking ISSN: 10761551 NLM ISO Abbreviation: Mol Med Subsets: MEDLINE; PubMed not MEDLINE

A PARP2-specific active site α-helix melts to permit DNA damage-induced enzymatic activation.

Authors: Smith-Pillet ES Billur R Langelier MF et al.

Source: BioRxiv : the preprint server for biology [bioRxiv] 2024 May 20. Date of Electronic Publication: 2024 May 20.

Publication Type: Journal Article; Preprint

Journal Info: Country of Publication: United States NLM ID: 101680187 Publication Model: Electronic Cited Medium: Internet ISSN: 2692-8205 (Electronic) Linking ISSN: 26928205 NLM ISO Abbreviation: bioRxiv Subsets: PubMed not MEDLINE

2-O, 3-O desulfated heparin (ODSH) increases bacterial clearance and attenuates lung injury in cystic fibrosis by restoring HMGB1-compromised macrophage function.

Authors: Wang M Gauthier AG Kennedy TP et al.

Source: Molecular medicine (Cambridge, Mass.) [Mol Med] 2021 Jul 16; Vol. 27 (1), pp. 79. Date of Electronic Publication: 2021 Jul 16.

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

Journal Info: Publisher: BioMed Central Country of Publication: England NLM ID: 9501023 Publication Model: Electronic Cited Medium: Internet ISSN: 1528-3658 (Electronic) Linking ISSN: 10761551 NLM ISO Abbreviation: Mol Med Subsets: MEDLINE

Structural basis for allosteric PARP-1 retention on DNA breaks.

Authors: Zandarashvili L Langelier MF Velagapudi UK et al.

Source: Science (New York, N.Y.) [Science] 2020 Apr 03; Vol. 368 (6486).

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

Journal Info: Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 0404511 Publication Model: Print Cited Medium: Internet ISSN: 1095-9203 (Electronic) Linking ISSN: 00368075 NLM ISO Abbreviation: Science Subsets: MEDLINE

Identification of a novel spirocyclic Nek2 inhibitor using high throughput virtual screening.

Authors: Bhuiyan AI Choi AH Ghoshal S et al.

Source: Bioorganic & medicinal chemistry letters [Bioorg Med Chem Lett] 2023 May 15; Vol. 88, pp. 129288. Date of Electronic Publication: 2023 Apr 23.

Publication Type: Journal Article; Research Support, N.I.H., Extramural

Journal Info: Publisher: Elsevier Science Ltd Country of Publication: England NLM ID: 9107377 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1464-3405 (Electronic) Linking ISSN: 0960894X NLM ISO Abbreviation: Bioorg Med Chem Lett Subsets: MEDLINE

The molluscum contagiosum virus death effector domain containing protein MC160 RxDL motifs are not required for its known viral immune evasion functions.

Authors: Beaury M Velagapudi UK Weber S et al.

Source: Virus genes [Virus Genes] 2017 Aug; Vol. 53 (4), pp. 522-531. Date of Electronic Publication: 2017 Apr 20.

Publication Type: Journal Article

Journal Info: Publisher: Kluwer Academic Country of Publication: United States NLM ID: 8803967 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1572-994X (Electronic) Linking ISSN: 09208569 NLM ISO Abbreviation: Virus Genes Subsets: MEDLINE

The ubiquitin-dependent ATPase p97 removes cytotoxic trapped PARP1 from chromatin.

Authors: Krastev DB Li S Sun Y et al.

Source: Nature cell biology [Nat Cell Biol] 2022 Jan; Vol. 24 (1), pp. 62-73. Date of Electronic Publication: 2022 Jan 10.

Publication Type: Journal Article; Research Support, N.I.H., Intramural; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Macmillan Magazines Ltd Country of Publication: England NLM ID: 100890575 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-4679 (Electronic) Linking ISSN: 14657392 NLM ISO Abbreviation: Nat Cell Biol Subsets: MEDLINE

In Vitro Antibacterial Activity of Rhodanine Derivatives against Pathogenic Clinical Isolates.

Authors: AbdelKhalek A Ashby CR Jr Patel BA et al.

Source: PloS one [PLoS One] 2016 Oct 06; Vol. 11 (10), pp. e0164227. Date of Electronic Publication: 2016 Oct 06 (Print Publication: 2016).

Publication Type: Journal Article

Journal Info: Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection Cited Medium: Internet ISSN: 1932-6203 (Electronic) Linking ISSN: 19326203 NLM ISO Abbreviation: PLoS One Subsets: MEDLINE

Characterization of Solid Dispersion of Itraconazole Prepared by Solubilization in Concentrated Aqueous Solutions of Weak Organic Acids and Drying.

Authors: Parikh T Sandhu HK Talele TT et al.

Source: Pharmaceutical research [Pharm Res] 2016 Jun; Vol. 33 (6), pp. 1456-71. Date of Electronic Publication: 2016 Mar 07.

Publication Type: Journal Article

Journal Info: Publisher: Kluwer Academic/Plenum Publishers Country of Publication: United States NLM ID: 8406521 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1573-904X (Electronic) Linking ISSN: 07248741 NLM ISO Abbreviation: Pharm Res Subsets: MEDLINE

Recent development in the discovery of PARP inhibitors as anticancer agents: a patent update (2016-2020).

Authors: Velagapudi UK Patel BA Shao X et al.

Source: Expert opinion on therapeutic patents [Expert Opin Ther Pat] 2021 Jul; Vol. 31 (7), pp. 609-623. Date of Electronic Publication: 2021 Mar 12.

Publication Type: Journal Article; Review

Journal Info: Publisher: Informa Healthcare Country of Publication: England NLM ID: 9516419 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1744-7674 (Electronic) Linking ISSN: 13543776 NLM ISO Abbreviation: Expert Opin Ther Pat Subsets: MEDLINE

Opportunities for Tapping into Three-Dimensional Chemical Space through a Quaternary Carbon.

Authors: Talele TT; Department of Pharmaceutical Sciences, College of Pharmacy and Health Sciences, St. John's University, Queens, New York 11439, United States.

Source: Journal of medicinal chemistry [J Med Chem] 2020 Nov 25; Vol. 63 (22), pp. 13291-13315. Date of Electronic Publication: 2020 Aug 31.

Publication Type: Journal Article; Review

Journal Info: Publisher: American Chemical Society Country of Publication: United States NLM ID: 9716531 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1520-4804 (Electronic) Linking ISSN: 00222623 NLM ISO Abbreviation: J Med Chem Subsets: MEDLINE

Synthesis of 2,3-dihydrobenzo[b][1,4]dioxine-5-carboxamide and 3-oxo-3,4-dihydrobenzo[b][1,4]oxazine-8-carboxamide derivatives as PARP1 inhibitors.

Authors: Shao X Pak S Velagapudi UK et al.

Source: Bioorganic chemistry [Bioorg Chem] 2020 Sep; Vol. 102, pp. 104075. Date of Electronic Publication: 2020 Jul 08.

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Elsevier Country of Publication: United States NLM ID: 1303703 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1090-2120 (Electronic) Linking ISSN: 00452068 NLM ISO Abbreviation: Bioorg Chem Subsets: MEDLINE

Novel 4-thiazolidinones as non-nucleoside inhibitors of hepatitis C virus NS5B RNA-dependent RNA polymerase.

Authors: Çakir G Küçükgüzel İ Guhamazumder R et al.

Source: Archiv der Pharmazie [Arch Pharm (Weinheim)] 2015 Jan; Vol. 348 (1), pp. 10-22. Date of Electronic Publication: 2014 Dec 02.

Publication Type: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Wiley-VCH Verlag GmbH & Co. KGaA Country of Publication: Germany NLM ID: 0330167 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1521-4184 (Electronic) Linking ISSN: 03656233 NLM ISO Abbreviation: Arch Pharm (Weinheim) Subsets: MEDLINE

Anti-cancer and anti-hepatitis C virus NS5B polymerase activity of etodolac 1,2,4-triazoles.

Authors: Çıkla-Süzgün P Kaushik-Basu N Basu A et al.

Source: Journal of enzyme inhibition and medicinal chemistry [J Enzyme Inhib Med Chem] 2015; Vol. 30 (5), pp. 778-85.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Taylor & Francis Country of Publication: England NLM ID: 101150203 Publication Model: Print Cited Medium: Internet ISSN: 1475-6374 (Electronic) Linking ISSN: 14756366 NLM ISO Abbreviation: J Enzyme Inhib Med Chem Subsets: MEDLINE