Search Results - "Tarleton RL"

Highly cross-reactive and competent effectors dominate the CD8+ T cell response in Trypanosoma cruzi infection.

Authors: Bunkofske ME Dash P Awad W et al.

Source: Journal of immunology (Baltimore, Md. : 1950) [J Immunol] 2025 Aug 01; Vol. 214 (8), pp. 2000-2014.

Publication Type: Journal Article

Journal Info: Publisher: American Association of Immunologists Country of Publication: England NLM ID: 2985117R Publication Model: Print Cited Medium: Internet ISSN: 1550-6606 (Electronic) Linking ISSN: 00221767 NLM ISO Abbreviation: J Immunol Subsets: MEDLINE

Glycosomal Phosphoenolpyruvate Carboxykinase CRISPR/Cas9-Deletion and Its Role in Trypanosoma cruzi Metacyclogenesis and Infectivity in Mammalian Host.

Authors: Vieira CSD Wang W Sanchez-Valdez F et al.

Source: FASEB journal : official publication of the Federation of American Societies for Experimental Biology [FASEB J] 2026 Mar 31; Vol. 40 (6), pp. e71672.

Publication Type: Journal Article

Journal Info: Publisher: Federation of American Societies for Experimental Biology Country of Publication: United States NLM ID: 8804484 Publication Model: Print Cited Medium: Internet ISSN: 1530-6860 (Electronic) Linking ISSN: 08926638 NLM ISO Abbreviation: FASEB J Subsets: MEDLINE

Serial 'deep-sampling' PCR of fragmented DNA reveals the wide range of Trypanosoma cruzi burden among chronically infected human, macaque, and canine hosts, and allows accurate monitoring of parasite load following treatment.

Authors: White BE Hodo CL Hamer S et al.

Source: ELife [Elife] 2025 Apr 15; Vol. 14. Date of Electronic Publication: 2025 Apr 15.

Publication Type: Journal Article

Journal Info: Publisher: eLife Sciences Publications, Ltd Country of Publication: England NLM ID: 101579614 Publication Model: Electronic Cited Medium: Internet ISSN: 2050-084X (Electronic) Linking ISSN: 2050084X NLM ISO Abbreviation: Elife Subsets: MEDLINE

The importance of persistence and dormancy in Trypanosoma cruzi infection and Chagas disease.

Authors: Bunkofske ME Sanchez-Valdez FJ Tarleton RL

Source: Current opinion in microbiology [Curr Opin Microbiol] 2025 Aug; Vol. 86, pp. 102615. Date of Electronic Publication: 2025 Jun 06.

Publication Type: Journal Article; Review

Journal Info: Publisher: Current Biology Country of Publication: England NLM ID: 9815056 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-0364 (Electronic) Linking ISSN: 13695274 NLM ISO Abbreviation: Curr Opin Microbiol Subsets: MEDLINE

B-Cell Responses in Chronic Chagas Disease: Waning of Trypanosoma cruzi-Specific Antibody-Secreting Cells Following Successful Etiological Treatment.

Authors: Cesar G Natale MA Albareda MC et al.

Source: The Journal of infectious diseases [J Infect Dis] 2023 May 29; Vol. 227 (11), pp. 1322-1332.

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Oxford University Press Country of Publication: United States NLM ID: 0413675 Publication Model: Print Cited Medium: Internet ISSN: 1537-6613 (Electronic) Linking ISSN: 00221899 NLM ISO Abbreviation: J Infect Dis Subsets: MEDLINE

Avoiding Clinical Trial Failures in Neglected Tropical Diseases: The Example of Chagas Disease.

Authors: Tarleton RL; Center for Tropical and Emerging Global Diseases, University of Georgia, Athens, Georgia, USA.; The Chagas Disease Foundation, Bogart, Georgia, USA.

Source: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America [Clin Infect Dis] 2023 Apr 17; Vol. 76 (8), pp. 1516-1520.

Publication Type: Journal Article

Journal Info: Publisher: Oxford University Press Country of Publication: United States NLM ID: 9203213 Publication Model: Print Cited Medium: Internet ISSN: 1537-6591 (Electronic) Linking ISSN: 10584838 NLM ISO Abbreviation: Clin Infect Dis Subsets: MEDLINE

Prophylactic low-dose, bi-weekly benznidazole treatment fails to prevent Trypanosoma cruzi infection in dogs under intense transmission pressure.

Authors: Bustamante JM Padilla AM White B et al.

Source: PLoS neglected tropical diseases [PLoS Negl Trop Dis] 2022 Oct 31; Vol. 16 (10), pp. e0010688. Date of Electronic Publication: 2022 Oct 31 (Print Publication: 2022).

Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Extramural

Journal Info: Publisher: Public Library of Science Country of Publication: United States NLM ID: 101291488 Publication Model: eCollection Cited Medium: Internet ISSN: 1935-2735 (Electronic) Linking ISSN: 19352727 NLM ISO Abbreviation: PLoS Negl Trop Dis Subsets: MEDLINE

Serial 'deep-sampling' PCR of fragmented DNA reveals the wide range of Trypanosoma cruzi burden among chronically infected hosts and allows accurate monitoring of parasite load following treatment.

Authors: White BE Hodo CL Hamer SA et al.

Source: BioRxiv : the preprint server for biology [bioRxiv] 2024 Nov 05. Date of Electronic Publication: 2024 Nov 05.

Publication Type: Journal Article; Preprint

Journal Info: Country of Publication: United States NLM ID: 101680187 Publication Model: Electronic Cited Medium: Internet ISSN: 2692-8205 (Electronic) Linking ISSN: 26928205 NLM ISO Abbreviation: bioRxiv Subsets: PubMed not MEDLINE

Positive clinical outcome using a modified dosing regimen of benznidazole in dogs at high risk for infection or acutely infected with Trypanosoma cruzi.

Authors: Lim S Collins S Hamer SA et al.

Source: Journal of veterinary internal medicine [J Vet Intern Med] 2024 May-Jun; Vol. 38 (3), pp. 1725-1729. Date of Electronic Publication: 2024 Mar 18.

Publication Type: Journal Article; Case Reports

Journal Info: Publisher: Wiley Periodicals Country of Publication: United States NLM ID: 8708660 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1939-1676 (Electronic) Linking ISSN: 08916640 NLM ISO Abbreviation: J Vet Intern Med Subsets: MEDLINE

Immune exhaustion in chronic Chagas disease: Pro-inflammatory and immunomodulatory action of IL-27 in vitro.

Authors: Natale MA Minning T Albareda MC et al.

Source: PLoS neglected tropical diseases [PLoS Negl Trop Dis] 2021 Jun 01; Vol. 15 (6), pp. e0009473. Date of Electronic Publication: 2021 Jun 01 (Print Publication: 2021).

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Public Library of Science Country of Publication: United States NLM ID: 101291488 Publication Model: eCollection Cited Medium: Internet ISSN: 1935-2735 (Electronic) Linking ISSN: 19352727 NLM ISO Abbreviation: PLoS Negl Trop Dis Subsets: MEDLINE

Reduced Trypanosoma cruzi-specific humoral response and enhanced T cell immunity after treatment interruption with benznidazole in chronic Chagas disease.

Authors: Castro Eiro MD Natale MA Alvarez MG et al.

Source: The Journal of antimicrobial chemotherapy [J Antimicrob Chemother] 2021 May 12; Vol. 76 (6), pp. 1580-1592.

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Oxford University Press Country of Publication: England NLM ID: 7513617 Publication Model: Print Cited Medium: Internet ISSN: 1460-2091 (Electronic) Linking ISSN: 03057453 NLM ISO Abbreviation: J Antimicrob Chemother Subsets: MEDLINE

High variation in immune responses and parasite phenotypes in naturally acquired Trypanosoma cruzi infection in a captive non-human primate breeding colony in Texas, USA.

Authors: Padilla AM Yao PY Landry TJ et al.

Source: PLoS neglected tropical diseases [PLoS Negl Trop Dis] 2021 Mar 31; Vol. 15 (3), pp. e0009141. Date of Electronic Publication: 2021 Mar 31 (Print Publication: 2021).

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Public Library of Science Country of Publication: United States NLM ID: 101291488 Publication Model: eCollection Cited Medium: Internet ISSN: 1935-2735 (Electronic) Linking ISSN: 19352727 NLM ISO Abbreviation: PLoS Negl Trop Dis Subsets: MEDLINE

Strain-specific genome evolution in Trypanosoma cruzi, the agent of Chagas disease.

Authors: Wang W Peng D Baptista RP et al.

Source: PLoS pathogens [PLoS Pathog] 2021 Jan 28; Vol. 17 (1), pp. e1009254. Date of Electronic Publication: 2021 Jan 28 (Print Publication: 2021).

Publication Type: Journal Article; Research Support, N.I.H., Extramural

Journal Info: Publisher: Public Library of Science Country of Publication: United States NLM ID: 101238921 Publication Model: eCollection Cited Medium: Internet ISSN: 1553-7374 (Electronic) Linking ISSN: 15537366 NLM ISO Abbreviation: PLoS Pathog Subsets: MEDLINE

A modified drug regimen clears active and dormant trypanosomes in mouse models of Chagas disease.

Authors: Bustamante JM Sanchez-Valdez F Padilla AM et al.

Source: Science translational medicine [Sci Transl Med] 2020 Oct 28; Vol. 12 (567).

Publication Type: Journal Article; Research Support, N.I.H., Extramural

Journal Info: Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 101505086 Publication Model: Print Cited Medium: Internet ISSN: 1946-6242 (Electronic) Linking ISSN: 19466234 NLM ISO Abbreviation: Sci Transl Med Subsets: MEDLINE

cGAS-STING Pathway Activation during Trypanosoma cruzi Infection Leads to Tissue-Dependent Parasite Control.

Authors: Perumal N White B Sanchez-Valdez F et al.

Source: Journal of immunology (Baltimore, Md. : 1950) [J Immunol] 2023 Oct 01; Vol. 211 (7), pp. 1123-1133.

Publication Type: Journal Article; Research Support, N.I.H., Extramural

Journal Info: Publisher: Oxford University Press Country of Publication: England NLM ID: 2985117R Publication Model: Print Cited Medium: Internet ISSN: 1550-6606 (Electronic) Linking ISSN: 00221767 NLM ISO Abbreviation: J Immunol Subsets: MEDLINE

DIAGNOSIS AND TREATMENT OF A NATURAL INFECTION WITH TRYPANOSOMA CRUZI (CHAGAS DISEASE) IN A SYMPTOMATIC DE BRAZZA'S MONKEY (CERCOPITHECUS NEGLECTUS) IN ALABAMA.

Authors: McCain S Sim RR Weidner B et al.

Source: Journal of zoo and wildlife medicine : official publication of the American Association of Zoo Veterinarians [J Zoo Wildl Med] 2023 Jul; Vol. 54 (2), pp. 412-416.

Publication Type: Journal Article

Journal Info: Publisher: American Association Of Zoo Veterinarians Country of Publication: United States NLM ID: 8915208 Publication Model: Print Cited Medium: Internet ISSN: 1042-7260 (Print) Linking ISSN: 10427260 NLM ISO Abbreviation: J Zoo Wildl Med Subsets: MEDLINE

Effective drug discovery in Chagas disease.

Authors: Tarleton RL; Center for Tropical and Emerging Global Diseases, University of Georgia, Athens, GA 30602, USA. Electronic address: tarleton@uga.edu.

Source: Trends in parasitology [Trends Parasitol] 2023 Jun; Vol. 39 (6), pp. 423-431. Date of Electronic Publication: 2023 Apr 04.

Publication Type: Journal Article; Review; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Elsevier Science Country of Publication: England NLM ID: 100966034 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1471-5007 (Electronic) Linking ISSN: 14714922 NLM ISO Abbreviation: Trends Parasitol Subsets: MEDLINE

Frequency Variation and Dose Modification of Benznidazole Administration for the Treatment of Trypanosoma cruzi Infection in Mice, Dogs, and Nonhuman Primates.

Authors: Bustamante JM White BE Wilkerson GK et al.

Source: Antimicrobial agents and chemotherapy [Antimicrob Agents Chemother] 2023 May 17; Vol. 67 (5), pp. e0013223. Date of Electronic Publication: 2023 Apr 11.

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

Journal Info: Publisher: American Society for Microbiology Country of Publication: United States NLM ID: 0315061 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1098-6596 (Electronic) Linking ISSN: 00664804 NLM ISO Abbreviation: Antimicrob Agents Chemother Subsets: MEDLINE

Highly competent, non-exhausted CD8+ T cells continue to tightly control pathogen load throughout chronic Trypanosoma cruzi infection.

Authors: Pack AD Collins MH Rosenberg CS et al.

Source: PLoS pathogens [PLoS Pathog] 2018 Nov 12; Vol. 14 (11), pp. e1007410. Date of Electronic Publication: 2018 Nov 12 (Print Publication: 2018).

Publication Type: Journal Article; Research Support, N.I.H., Extramural

Journal Info: Publisher: Public Library of Science Country of Publication: United States NLM ID: 101238921 Publication Model: eCollection Cited Medium: Internet ISSN: 1553-7374 (Electronic) Linking ISSN: 15537366 NLM ISO Abbreviation: PLoS Pathog Subsets: MEDLINE

Distinct Treatment Outcomes of Antiparasitic Therapy in Trypanosoma cruzi-Infected Children Is Associated With Early Changes in Cytokines, Chemokines, and T-Cell Phenotypes.

Authors: Albareda MC Natale MA De Rissio AM et al.

Source: Frontiers in immunology [Front Immunol] 2018 Sep 13; Vol. 9, pp. 1958. Date of Electronic Publication: 2018 Sep 13 (Print Publication: 2018).

Publication Type: Clinical Trial; Journal Article; Multicenter Study; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Frontiers Research Foundation] Country of Publication: Switzerland NLM ID: 101560960 Publication Model: eCollection Cited Medium: Internet ISSN: 1664-3224 (Electronic) Linking ISSN: 16643224 NLM ISO Abbreviation: Front Immunol Subsets: MEDLINE