Search Results - "Taskar KS"

PBPK Modelling of PROTACs: Learnings from ARV-110 as a Case Example.

Authors: Salem F Tabatabaeian Nimavardi A Srivastava A et al.

Source: The AAPS journal [AAPS J] 2026 Mar 27; Vol. 28 (3). Date of Electronic Publication: 2026 Mar 27.

Publication Type: Journal Article

Journal Info: Publisher: American Association of Pharmaceutical Scientists Country of Publication: United States NLM ID: 101223209 Publication Model: Electronic Cited Medium: Internet ISSN: 1550-7416 (Electronic) Linking ISSN: 15507416 NLM ISO Abbreviation: AAPS J Subsets: MEDLINE

Strategy for Identifying Rational Sensitivity Analysis Using PBPK Modeling for Precipitant Drug-Drug Interaction Predictions.

Authors: Taskar KS Sharma P Rowland Yeo K

Source: Clinical pharmacology and therapeutics [Clin Pharmacol Ther] 2026 Feb; Vol. 119 (2), pp. 314-317. Date of Electronic Publication: 2025 Nov 13.

Publication Type: Journal Article

Journal Info: Publisher: Wiley Country of Publication: United States NLM ID: 0372741 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1532-6535 (Electronic) Linking ISSN: 00099236 NLM ISO Abbreviation: Clin Pharmacol Ther Subsets: MEDLINE

Building Confidence in Physiologically Based Pharmacokinetic Modeling of CYP3A Induction Mediated by Rifampin: An Industry Perspective.

Authors: Reddy MB Cabalu TD de Zwart L et al.

Source: Clinical pharmacology and therapeutics [Clin Pharmacol Ther] 2025 Feb; Vol. 117 (2), pp. 403-420. Date of Electronic Publication: 2024 Oct 18.

Publication Type: Journal Article; Review; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Wiley Country of Publication: United States NLM ID: 0372741 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1532-6535 (Electronic) Linking ISSN: 00099236 NLM ISO Abbreviation: Clin Pharmacol Ther Subsets: MEDLINE

Physiologically-Based Pharmacokinetic Modeling of the PARP Inhibitor Niraparib.

Authors: Lewis GJ Jewell RC Krishnatry AS et al.

Source: CPT: pharmacometrics & systems pharmacology [CPT Pharmacometrics Syst Pharmacol] 2026 Jan; Vol. 15 (1), pp. e70182.

Publication Type: Journal Article

Journal Info: Publisher: Wiley Country of Publication: United States NLM ID: 101580011 Publication Model: Print Cited Medium: Internet ISSN: 2163-8306 (Electronic) Linking ISSN: 21638306 NLM ISO Abbreviation: CPT Pharmacometrics Syst Pharmacol Subsets: MEDLINE

Physiologically-Based Pharmacokinetic Modeling to Support Pediatric Clinical Development: An IQ Working Group Perspective on the Current Status and Challenges.

Authors: Yates JWT Zientek M Taskar KS et al.

Source: CPT: pharmacometrics & systems pharmacology [CPT Pharmacometrics Syst Pharmacol] 2026 Jan; Vol. 15 (1), pp. e70141. Date of Electronic Publication: 2025 Nov 18.

Publication Type: Journal Article; Review

Journal Info: Publisher: Wiley Country of Publication: United States NLM ID: 101580011 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2163-8306 (Electronic) Linking ISSN: 21638306 NLM ISO Abbreviation: CPT Pharmacometrics Syst Pharmacol Subsets: MEDLINE

Matrix Approach Assessment of Cabotegravir Drug-Drug Interactions with OAT1/OAT3 Substrates and UGT1A1/UGT1A9 Inhibitors Using Physiologically-Based Pharmacokinetic Modeling.

Authors: Tracey H Bate ST Ford S et al.

Source: Pharmaceutics [Pharmaceutics] 2025 Apr 18; Vol. 17 (4). Date of Electronic Publication: 2025 Apr 18.

Publication Type: Journal Article

Journal Info: Publisher: MDPI Country of Publication: Switzerland NLM ID: 101534003 Publication Model: Electronic Cited Medium: Print ISSN: 1999-4923 (Print) Linking ISSN: 19994923 NLM ISO Abbreviation: Pharmaceutics Subsets: PubMed not MEDLINE

Development of a physiologically based pharmacokinetic model of fostemsavir and its pivotal application to support dosing in pregnancy.

Authors: Salem F Nguyen D Bush M et al.

Source: CPT: pharmacometrics & systems pharmacology [CPT Pharmacometrics Syst Pharmacol] 2024 Nov; Vol. 13 (11), pp. 1881-1892. Date of Electronic Publication: 2024 May 01.

Publication Type: Journal Article

Journal Info: Publisher: Wiley Country of Publication: United States NLM ID: 101580011 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2163-8306 (Electronic) Linking ISSN: 21638306 NLM ISO Abbreviation: CPT Pharmacometrics Syst Pharmacol Subsets: MEDLINE

Clinical Relevance of Hepatic and Renal P-gp/BCRP Inhibition of Drugs: An International Transporter Consortium Perspective.

Authors: Taskar KS Yang X Neuhoff S et al.

Corporate Authors: Taskar KS Yang X Neuhoff S et al.

Source: Clinical pharmacology and therapeutics [Clin Pharmacol Ther] 2022 Sep; Vol. 112 (3), pp. 573-592. Date of Electronic Publication: 2022 Jun 22.

Publication Type: Journal Article; Review; Research Support, N.I.H., Extramural

Journal Info: Publisher: Wiley Country of Publication: United States NLM ID: 0372741 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1532-6535 (Electronic) Linking ISSN: 00099236 NLM ISO Abbreviation: Clin Pharmacol Ther Subsets: MEDLINE

Industrial Perspective on the Benefits Realized From the FDA's Model-Informed Drug Development Paired Meeting Pilot Program.

Authors: Galluppi GR Brar S Caro L et al.

Source: Clinical pharmacology and therapeutics [Clin Pharmacol Ther] 2021 Nov; Vol. 110 (5), pp. 1172-1175. Date of Electronic Publication: 2021 May 15.

Publication Type: Journal Article; Review

Journal Info: Publisher: Wiley Country of Publication: United States NLM ID: 0372741 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1532-6535 (Electronic) Linking ISSN: 00099236 NLM ISO Abbreviation: Clin Pharmacol Ther Subsets: MEDLINE

Physiologically-based pharmacokinetic modeling of prominent oral contraceptive agents and applications in drug-drug interactions.

Authors: Lewis GJ Ahire D Taskar KS

Source: CPT: pharmacometrics & systems pharmacology [CPT Pharmacometrics Syst Pharmacol] 2024 Apr; Vol. 13 (4), pp. 563-575. Date of Electronic Publication: 2024 Jan 15.

Publication Type: Journal Article

Journal Info: Publisher: Wiley Country of Publication: United States NLM ID: 101580011 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2163-8306 (Electronic) Linking ISSN: 21638306 NLM ISO Abbreviation: CPT Pharmacometrics Syst Pharmacol Subsets: MEDLINE

When special populations intersect with drug-drug interactions: Application of physiologically-based pharmacokinetic modeling in pregnant populations.

Authors: Sychterz C Galetin A Taskar KS

Source: Biopharmaceutics & drug disposition [Biopharm Drug Dispos] 2021 Apr; Vol. 42 (4), pp. 160-177. Date of Electronic Publication: 2021 Apr 26.

Publication Type: Journal Article; Review

Journal Info: Publisher: Wiley Country of Publication: England NLM ID: 7911226 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1099-081X (Electronic) Linking ISSN: 01422782 NLM ISO Abbreviation: Biopharm Drug Dispos Subsets: MEDLINE

Intestinal P-gp and Putative Hepatic OATP1B Induction: International Transporter Consortium Perspective on Drug Development Implications.

Authors: Zamek-Gliszczynski MJ Patel M Yang X et al.

Source: Clinical pharmacology and therapeutics [Clin Pharmacol Ther] 2021 Jan; Vol. 109 (1), pp. 55-64. Date of Electronic Publication: 2020 Jul 09.

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Review

Journal Info: Publisher: Wiley Country of Publication: United States NLM ID: 0372741 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1532-6535 (Electronic) Linking ISSN: 00099236 NLM ISO Abbreviation: Clin Pharmacol Ther Subsets: MEDLINE

Physiologically-Based Pharmacokinetic Models for Evaluating Membrane Transporter Mediated Drug-Drug Interactions: Current Capabilities, Case Studies, Future Opportunities, and Recommendations.

Authors: Taskar KS Pilla Reddy V Burt H et al.

Source: Clinical pharmacology and therapeutics [Clin Pharmacol Ther] 2020 May; Vol. 107 (5), pp. 1082-1115. Date of Electronic Publication: 2019 Dec 31.

Publication Type: Journal Article; Review

Journal Info: Publisher: Wiley Country of Publication: United States NLM ID: 0372741 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1532-6535 (Electronic) Linking ISSN: 00099236 NLM ISO Abbreviation: Clin Pharmacol Ther Subsets: MEDLINE

Physiologically based pharmacokinetic modeling for development and applications of a virtual celiac disease population using felodipine as a model drug.

Authors: Salem F Nimavardi A Mudunuru J et al.

Source: CPT: pharmacometrics & systems pharmacology [CPT Pharmacometrics Syst Pharmacol] 2023 Jun; Vol. 12 (6), pp. 808-820. Date of Electronic Publication: 2023 Apr 02.

Publication Type: Journal Article

Journal Info: Publisher: Wiley Country of Publication: United States NLM ID: 101580011 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2163-8306 (Electronic) Linking ISSN: 21638306 NLM ISO Abbreviation: CPT Pharmacometrics Syst Pharmacol Subsets: MEDLINE

Can Bile Salt Export Pump Inhibition Testing in Drug Discovery and Development Reduce Liver Injury Risk? An International Transporter Consortium Perspective.

Authors: Kenna JG Taskar KS Battista C et al.

Corporate Authors: Kenna JG Taskar KS Battista C et al.

Source: Clinical pharmacology and therapeutics [Clin Pharmacol Ther] 2018 Nov; Vol. 104 (5), pp. 916-932.

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Review

Journal Info: Publisher: Wiley Country of Publication: United States NLM ID: 0372741 Publication Model: Print Cited Medium: Internet ISSN: 1532-6535 (Electronic) Linking ISSN: 00099236 NLM ISO Abbreviation: Clin Pharmacol Ther Subsets: MEDLINE

Endogenous Probes for Drug Transporters: Balancing Vision With Reality.

Authors: Rodrigues AD Taskar KS Kusuhara H et al.

Source: Clinical pharmacology and therapeutics [Clin Pharmacol Ther] 2018 Mar; Vol. 103 (3), pp. 434-448. Date of Electronic Publication: 2017 Jul 14.

Publication Type: Journal Article; Review

Journal Info: Publisher: Wiley Country of Publication: United States NLM ID: 0372741 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1532-6535 (Electronic) Linking ISSN: 00099236 NLM ISO Abbreviation: Clin Pharmacol Ther Subsets: MEDLINE

Robust physiologically based pharmacokinetic model of rifampicin for predicting drug-drug interactions via P-glycoprotein induction and inhibition in the intestine, liver, and kidney.

Authors: Asaumi R Nunoya KI Yamaura Y et al.

Source: CPT: pharmacometrics & systems pharmacology [CPT Pharmacometrics Syst Pharmacol] 2022 Jul; Vol. 11 (7), pp. 919-933. Date of Electronic Publication: 2022 Jun 06.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Wiley Country of Publication: United States NLM ID: 101580011 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2163-8306 (Electronic) Linking ISSN: 21638306 NLM ISO Abbreviation: CPT Pharmacometrics Syst Pharmacol Subsets: MEDLINE

Importance of Hepatic Transporters in Clinical Disposition of Drugs and Their Metabolites.

Authors: Patel M Taskar KS Zamek-Gliszczynski MJ

Source: Journal of clinical pharmacology [J Clin Pharmacol] 2016 Jul; Vol. 56 Suppl 7, pp. S23-39.

Publication Type: Journal Article; Review

Journal Info: Publisher: Wiley Country of Publication: England NLM ID: 0366372 Publication Model: Print Cited Medium: Internet ISSN: 1552-4604 (Electronic) Linking ISSN: 00912700 NLM ISO Abbreviation: J Clin Pharmacol Subsets: MEDLINE

Physiologically-based Pharmacokinetic (PBPK) Modelling of Transporter Mediated Drug Absorption, Clearance and Drug-drug Interactions.

Authors: Taskar KS Harada I Alluri RV

Source: Current drug metabolism [Curr Drug Metab] 2021; Vol. 22 (7), pp. 523-531.

Publication Type: Journal Article; Review

Journal Info: Publisher: Bentham Science Publishers Country of Publication: Netherlands NLM ID: 100960533 Publication Model: Print Cited Medium: Internet ISSN: 1875-5453 (Electronic) Linking ISSN: 13892002 NLM ISO Abbreviation: Curr Drug Metab Subsets: MEDLINE

Lapatinib distribution in HER2 overexpressing experimental brain metastases of breast cancer.

Authors: Taskar KS Rudraraju V Mittapalli RK et al.

Source: Pharmaceutical research [Pharm Res] 2012 Mar; Vol. 29 (3), pp. 770-81. Date of Electronic Publication: 2011 Oct 20.

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Kluwer Academic/Plenum Publishers Country of Publication: United States NLM ID: 8406521 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1573-904X (Electronic) Linking ISSN: 07248741 NLM ISO Abbreviation: Pharm Res Subsets: MEDLINE