Search Results - "Tong, Linjiang"

Dual targeting of VEGFR2 and CSF1R with SYHA1813 confers novel strategy for treating both BRAF wild-type and mutant melanoma.

Authors: Shi, Wenhao Tang, Haotian Tong, Linjiang et al.

Source: Cancer Cell International. 7/25/2025, Vol. 25 Issue 1, p1-12. 12p.

Synthesis of 7-Triazole-substituted Camptothecin via Click Chemistry and Evaluation of in vitro Antitumor Activity.

Authors: Wang, Lei Yuan, Wei Zhang, Jie et al.

Source: Chinese Journal of Chemistry; Feb2014, Vol. 32 Issue 2, p157-162, 6p

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Discovery of a novel third-generation EGFR inhibitor and identification of a potential combination strategy to overcome resistance.

Authors: Zhang, Tao Qu, Rong Chan, Shingpan et al.

Source: Molecular Cancer. 5/13/2020, Vol. 19 Issue 1, p1-15. 15p. 1 Color Photograph, 1 Chart, 5 Graphs.

Naphthalimides exhibit in vitro antiproliferative and antiangiogenic activities by inhibiting both topoisomerase II (topo II) and receptor tyrosine kinases (RTKs).

Authors: Wang, Xin Chen, Zhuo Tong, Linjiang et al.

Source: European Journal of Medicinal Chemistry. Jul2013, Vol. 65, p477-486. 10p.

The discovery of colchicine-SAHA hybrids as a new class of antitumor agents.

Authors: Zhang, Xuan Zhang, Jie Tong, Linjiang et al.

Source: Bioorganic & Medicinal Chemistry. Jun2013, Vol. 21 Issue 11, p3240-3244. 5p.

Synthesis and biological evaluation of new homocamptothecin analogs

Authors: Luo, Yu Yu, Shanbao Tong, Linjiang et al.

Source: European Journal of Medicinal Chemistry. Aug2012, Vol. 54, p281-286. 6p.

Discovery of novel selective inhibitors for EGFR-T790M/L858R

Authors: Bai, Fang Liu, Hongyan Tong, Linjiang et al.

Source: Bioorganic & Medicinal Chemistry Letters. Feb2012, Vol. 22 Issue 3, p1365-1370. 6p.

Correction: Discovery of a novel third-generation EGFR inhibitor and identification of a potential combination strategy to overcome resistance.

Authors: Zhang, Tao Qu, Rong Chan, Shingpan et al.

Source: Molecular Cancer. 8/19/2023, Vol. 22 Issue 1, p1-2. 2p.

18F-Labeled o‑aminopyridyl alkynyl radioligands targeting colony-stimulating factor 1 receptor for neuroinflammation imaging.

Authors: An, Xiaodan Wang, Jingqi Tong, Linjiang et al.

Source: Bioorganic & Medicinal Chemistry. Apr2023, Vol. 83, pN.PAG-N.PAG. 1p.

Discovery of 1,3-Diaryl-pyridones as Potent VEGFR-2 Inhibitors: Design, Synthesis, and Biological Evaluation.

Authors: Yan, Wei Huang, Zhaoru Wang, Zhengyu et al.

Source: Chemical Biology & Drug Design. May2016, Vol. 87 Issue 5, p694-703. 10p.

Design and synthesis of selective degraders of EGFRL858R/T790M mutant.

Authors: Zhang, Xin Xu, Fang Tong, Linjiang et al.

Source: European Journal of Medicinal Chemistry. Apr2020, Vol. 192, pN.PAG-N.PAG. 1p.

Discovery and Biological evaluation of pyrimido[4,5-d]pyrimidine-2,4(1H,3H)-dione derivatives as potent Bruton's tyrosine kinase inhibitors.

Authors: Diao, Yanyan Fang, Xiaoyu Song, Peiran et al.

Source: Bioorganic & Medicinal Chemistry. Aug2019, Vol. 27 Issue 15, p3390-3395. 6p.

Pyrazolo[4,3-b]pyrimido[4,5-e][1,4]diazepine derivatives as new multi-targeted inhibitors of Aurora A/B and KDR.

Authors: Zhang, Qiumeng Shen, Qianqian Gao, Lixin et al.

Source: European Journal of Medicinal Chemistry. Oct2018, Vol. 158, p428-441. 14p.

Correction to: Discovery of a novel third-generation EGFR inhibitor and identification of a potential combination strategy to overcome resistance.

Authors: Zhang, Tao Qu, Rong Chan, Shingpan et al.

Source: Molecular Cancer. 8/17/2021, Vol. 20 Issue 1, p1-1. 1p.

Discovery of novel 2,4-diarylaminopyrimidine derivatives as potent and selective epidermal growth factor receptor (EGFR) inhibitors against L858R/T790M resistance mutation.

Authors: Yan, Qi Chen, Yuzhe Tang, Baiyou et al.

Source: European Journal of Medicinal Chemistry. May2018, Vol. 152, p298-306. 9p.

Structure-based design and synthesis of 2,4-diaminopyrimidines as EGFR L858R/T790M selective inhibitors for NSCLC.

Authors: Chen, Lingfeng Fu, Weitao Feng, Chen et al.

Source: European Journal of Medicinal Chemistry. Nov2017, Vol. 140, p510-527. 18p.

C-H Trifluoromethylation of 2-Substituted/Unsubstituted Aminonaphthoquinones at Room Temperature with Bench-Stable (CF3SO2)2Zn: Synthesis and Antiproliferative Evaluation.

Authors: Li, Jing Zhang, Xiaofei Xiang, Haoyue et al.

Source: Journal of Organic Chemistry. 7/7/2017, Vol. 82 Issue 13, p6795-6800. 6p.

A structure-guided optimization of pyrido[2,3-d]pyrimidin-7-ones as selective inhibitors of EGFRL858R/T790M mutant with improved pharmacokinetic properties.

Authors: Yu, Lei Huang, Minhao Xu, Tianfeng et al.

Source: European Journal of Medicinal Chemistry. Jan2017, Vol. 126, p1107-1117. 11p.

Discovery of 5-(methylthio)pyrimidine derivatives as L858R/T790M mutant selective epidermal growth factor receptor (EGFR) inhibitors.

Authors: Xiao, Qiang Qu, Rong Gao, Dingding et al.

Source: Bioorganic & Medicinal Chemistry. Jun2016, Vol. 24 Issue 12, p2673-2680. 8p.