Search Results - "Topper MJ"

Defining UHRF1 Domains that Support Maintenance of Human Colon Cancer DNA Methylation and Oncogenic Properties.

Authors: Kong X Chen J Xie W et al.

Source: Cancer cell [Cancer Cell] 2026 Jul 17. Date of Electronic Publication: 2026 Jul 17.

Publication Type: Published Erratum

Journal Info: Publisher: Cell Press Country of Publication: United States NLM ID: 101130617 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1878-3686 (Electronic) Linking ISSN: 15356108 NLM ISO Abbreviation: Cancer Cell Subsets: MEDLINE

Bone marrow immunosuppressive states associate with survival after guadecitabine and atezolizumab therapy in HMA-R/R MDS.

Authors: Jang HJ Urrutia G Ørskov AD et al.

Source: Blood neoplasia [Blood Neoplasia] 2026 May 05; Vol. 3 (3), pp. 100243. Date of Electronic Publication: 2026 May 05 (Print Publication: 2026).

Publication Type: Journal Article

Journal Info: Publisher: Elsevier, Inc Country of Publication: United States NLM ID: 9918841988906676 Publication Model: eCollection Cited Medium: Internet ISSN: 2950-3280 (Electronic) Linking ISSN: 29503280 NLM ISO Abbreviation: Blood Neoplasia Subsets: PubMed not MEDLINE

MYC plus class IIa HDAC inhibition drives mitochondrial dysfunction in non-small cell lung cancer.

Authors: Park J Chen YY Cao JJ et al.

Source: Cell reports [Cell Rep] 2025 Jun 24; Vol. 44 (6), pp. 115722. Date of Electronic Publication: 2025 May 19.

Publication Type: Journal Article

Journal Info: Publisher: Cell Press Country of Publication: United States NLM ID: 101573691 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2211-1247 (Electronic) NLM ISO Abbreviation: Cell Rep Subsets: MEDLINE

ZNFX1 Functions as a Master Regulator of Epigenetically Induced Pathogen Mimicry and Inflammasome Signaling in Cancer.

Authors: Stojanovic L Abbotts R Tripathi K et al.

Source: Cancer research [Cancer Res] 2025 Apr 03; Vol. 85 (7), pp. 1183-1198.

Publication Type: Journal Article

Journal Info: Publisher: American Association for Cancer Research Country of Publication: United States NLM ID: 2984705R Publication Model: Print Cited Medium: Internet ISSN: 1538-7445 (Electronic) Linking ISSN: 00085472 NLM ISO Abbreviation: Cancer Res Subsets: MEDLINE

Lethal COVID-19 associates with RAAS-induced inflammation for multiple organ damage including mediastinal lymph nodes.

Authors: Topper MJ Guarnieri JW Haltom JA et al.

Source: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2024 Dec 03; Vol. 121 (49), pp. e2401968121. Date of Electronic Publication: 2024 Nov 27.

Publication Type: Journal Article

Journal Info: Publisher: National Academy of Sciences Country of Publication: United States NLM ID: 7505876 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1091-6490 (Electronic) Linking ISSN: 00278424 NLM ISO Abbreviation: Proc Natl Acad Sci U S A Subsets: MEDLINE

Bone marrow microenvironment signatures associate with patient survival after guadecitabine and atezolizumab therapy in HMA-resistant MDS.

Authors: Jang HJ Urrutia G Orskov AD et al.

Source: BioRxiv : the preprint server for biology [bioRxiv] 2024 Nov 11. Date of Electronic Publication: 2024 Nov 11.

Publication Type: Journal Article; Preprint

Journal Info: Country of Publication: United States NLM ID: 101680187 Publication Model: Electronic Cited Medium: Internet ISSN: 2692-8205 (Electronic) Linking ISSN: 26928205 NLM ISO Abbreviation: bioRxiv Subsets: PubMed not MEDLINE

ZNFX1 is a Novel Master Regulator in Epigenetically-induced Pathogen Mimicry and Inflammasome Signaling in Cancer.

Authors: Stojanovic L Abbotts R Tripathi K et al.

Source: BioRxiv : the preprint server for biology [bioRxiv] 2024 Oct 21. Date of Electronic Publication: 2024 Oct 21.

Publication Type: Journal Article; Preprint

Journal Info: Country of Publication: United States NLM ID: 101680187 Publication Model: Electronic Cited Medium: Internet ISSN: 2692-8205 (Electronic) Linking ISSN: 26928205 NLM ISO Abbreviation: bioRxiv Subsets: PubMed not MEDLINE

Select EZH2 inhibitors enhance viral mimicry effects of DNMT inhibition through a mechanism involving NFAT:AP-1 signaling.

Authors: Chomiak AA Tiedemann RL Liu Y et al.

Source: Science advances [Sci Adv] 2024 Mar 29; Vol. 10 (13), pp. eadk4423. Date of Electronic Publication: 2024 Mar 27.

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

Journal Info: Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 101653440 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2375-2548 (Electronic) Linking ISSN: 23752548 NLM ISO Abbreviation: Sci Adv Subsets: MEDLINE

Derivation of CD8⁺ T cell infiltration potentiators in non-small-cell lung cancer through tumor microenvironment analysis.

Authors: Topper MJ Anagnostou V Marrone KA et al.

Source: IScience [iScience] 2023 Jun 10; Vol. 26 (7), pp. 107095. Date of Electronic Publication: 2023 Jun 10 (Print Publication: 2023).

Publication Type: Journal Article

Journal Info: Publisher: Cell Press Country of Publication: United States NLM ID: 101724038 Publication Model: eCollection Cited Medium: Internet ISSN: 2589-0042 (Electronic) Linking ISSN: 25890042 NLM ISO Abbreviation: iScience Subsets: PubMed not MEDLINE

A Phase II Trial of Guadecitabine plus Atezolizumab in Metastatic Urothelial Carcinoma Progressing after Initial Immune Checkpoint Inhibitor Therapy.

Authors: Jang HJ Hostetter G Macfarlane AW et al.

Source: Clinical cancer research : an official journal of the American Association for Cancer Research [Clin Cancer Res] 2023 Jun 01; Vol. 29 (11), pp. 2052-2065.

Publication Type: Clinical Trial, Phase II; Journal Article; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Extramural

Journal Info: Publisher: American Association for Cancer Research Country of Publication: United States NLM ID: 9502500 Publication Model: Print Cited Medium: Internet ISSN: 1557-3265 (Electronic) Linking ISSN: 10780432 NLM ISO Abbreviation: Clin Cancer Res Subsets: MEDLINE

A comprehensive SARS-CoV-2 and COVID-19 review, Part 1: Intracellular overdrive for SARS-CoV-2 infection.

Authors: Jamison DA Jr Anand Narayanan S Trovão NS et al.

Source: European journal of human genetics : EJHG [Eur J Hum Genet] 2022 Aug; Vol. 30 (8), pp. 889-898. Date of Electronic Publication: 2022 May 16.

Publication Type: Journal Article; Review; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.

Journal Info: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 9302235 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-5438 (Electronic) Linking ISSN: 10184813 NLM ISO Abbreviation: Eur J Hum Genet Subsets: MEDLINE

Activating STING1-dependent immune signaling in TP53 mutant and wild-type acute myeloid leukemia.

Authors: Kogan AA Topper MJ Dellomo AJ et al.

Source: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2022 Jul 05; Vol. 119 (27), pp. e2123227119. Date of Electronic Publication: 2022 Jun 27.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Extramural

Journal Info: Publisher: National Academy of Sciences Country of Publication: United States NLM ID: 7505876 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1091-6490 (Electronic) Linking ISSN: 00278424 NLM ISO Abbreviation: Proc Natl Acad Sci U S A Subsets: MEDLINE

Epigenetic Therapies in Ovarian Cancer Alter Repetitive Element Expression in a TP53-Dependent Manner.

Authors: McDonald JI Diab N Arthofer E et al.

Source: Cancer research [Cancer Res] 2021 Oct 15; Vol. 81 (20), pp. 5176-5189. Date of Electronic Publication: 2021 Aug 25.

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

Journal Info: Publisher: American Association for Cancer Research Country of Publication: United States NLM ID: 2984705R Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1538-7445 (Electronic) Linking ISSN: 00085472 NLM ISO Abbreviation: Cancer Res Subsets: MEDLINE

Pharmacologic induction of innate immune signaling directly drives homologous recombination deficiency.

Authors: McLaughlin LJ Stojanovic L Kogan AA et al.

Source: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2020 Jul 28; Vol. 117 (30), pp. 17785-17795. Date of Electronic Publication: 2020 Jul 10.

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.

Journal Info: Publisher: National Academy of Sciences Country of Publication: United States NLM ID: 7505876 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1091-6490 (Electronic) Linking ISSN: 00278424 NLM ISO Abbreviation: Proc Natl Acad Sci U S A Subsets: MEDLINE

Epigenetic therapy inhibits metastases by disrupting premetastatic niches.

Authors: Lu Z Zou J Li S et al.

Source: Nature [Nature] 2020 Mar; Vol. 579 (7798), pp. 284-290. Date of Electronic Publication: 2020 Feb 26.

Publication Type: Journal Article

Journal Info: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 0410462 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-4687 (Electronic) Linking ISSN: 00280836 NLM ISO Abbreviation: Nature Subsets: MEDLINE

The emerging role of epigenetic therapeutics in immuno-oncology.

Authors: Topper MJ Vaz M Marrone KA et al.

Source: Nature reviews. Clinical oncology [Nat Rev Clin Oncol] 2020 Feb; Vol. 17 (2), pp. 75-90. Date of Electronic Publication: 2019 Sep 23.

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.; Review

Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101500077 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1759-4782 (Electronic) Linking ISSN: 17594774 NLM ISO Abbreviation: Nat Rev Clin Oncol Subsets: MEDLINE

DNA methyltransferase inhibitors induce a BRCAness phenotype that sensitizes NSCLC to PARP inhibitor and ionizing radiation.

Authors: Abbotts R Topper MJ Biondi C et al.

Source: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2019 Nov 05; Vol. 116 (45), pp. 22609-22618. Date of Electronic Publication: 2019 Oct 07.

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

Journal Info: Publisher: National Academy of Sciences Country of Publication: United States NLM ID: 7505876 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1091-6490 (Electronic) Linking ISSN: 00278424 NLM ISO Abbreviation: Proc Natl Acad Sci U S A Subsets: MEDLINE

Defining UHRF1 Domains that Support Maintenance of Human Colon Cancer DNA Methylation and Oncogenic Properties.

Authors: Kong X Chen J Xie W et al.

Source: Cancer cell [Cancer Cell] 2019 Apr 15; Vol. 35 (4), pp. 633-648.e7. Date of Electronic Publication: 2019 Apr 04.

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Cell Press Country of Publication: United States NLM ID: 101130617 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1878-3686 (Electronic) Linking ISSN: 15356108 NLM ISO Abbreviation: Cancer Cell Subsets: MEDLINE

Reply to Haffner et al.: DNA hypomethylation renders tumors more immunogenic.

Authors: Stone ML Chiappinelli KB Li H et al.

Source: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2018 Sep 11; Vol. 115 (37), pp. E8583-E8584. Date of Electronic Publication: 2018 Sep 04.

Publication Type: Letter; Comment

Journal Info: Publisher: National Academy of Sciences Country of Publication: United States NLM ID: 7505876 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1091-6490 (Electronic) Linking ISSN: 00278424 NLM ISO Abbreviation: Proc Natl Acad Sci U S A Subsets: MEDLINE

Reflections and inspirations: my year as your AVMA president.

Authors: Topper MJ

Source: Journal of the American Veterinary Medical Association [J Am Vet Med Assoc] 2018 Jul 01; Vol. 253 (1), pp. 10.

Publication Type: Journal Article

Journal Info: Publisher: American Veterinary Medical Association Country of Publication: United States NLM ID: 7503067 Publication Model: Print Cited Medium: Internet ISSN: 1943-569X (Electronic) Linking ISSN: 00031488 NLM ISO Abbreviation: J Am Vet Med Assoc Subsets: PubMed not MEDLINE