Search Results - "Tree, Timothy"

An international consensus on screening and monitoring early‐stage type 1 diabetes: A roadmap to European implementation.

Authors: Hussain, Sufyan Tree, Timothy Mathieu, Chantal et al.

Source: Diabetes, Obesity & Metabolism. May2026, Vol. 28 Issue 5, p3535-3556. 22p.

This result is not displayed to guests.
Login for full access.

Minimum effective low dose of antithymocyte globulin in people aged 5–25 years with recent-onset stage 3 type 1 diabetes (MELD-ATG): a phase 2, multicentre, double-blind, randomised, placebo-controlled, adaptive dose-ranging trial.

Authors: Mathieu, Chantal Wych, Julie Hendriks, A Emile J et al.

Source: Lancet. 9/27/2025, Vol. 406 Issue 10510, p1375-1388. 14p.

Subjects: Type 1 diabetes, Immunosuppressive agents, Experimental design, Young adults, Clinical trials, Therapeutics, Biomarkers

Efficacy and safety of low-dose IL-2 as an add-on therapy to riluzole (MIROCALS): a phase 2b, double-blind, randomised, placebo-controlled trial.

Authors: Bensimon, Gilbert Leigh, P Nigel Tree, Timothy et al.

Source: Lancet. May2025, Vol. 405 Issue 10492, p1837-1850. 14p.

Subjects: Amyotrophic lateral sclerosis, Regulatory T cells, Subcutaneous injections, Random measures, Cerebrospinal fluid

This result is not displayed to guests.
Login for full access.

A Mini Meta-Analysis of Studies on CD4⁺CD25⁺ T cells in Human Type 1 Diabetes.

Authors: TREE, TIMOTHY I.M. ROEP, BART O. PEAKMAN, MARK

Source: Annals of the New York Academy of Sciences. 2006, Vol. 1079 Issue 1, p9-18. 10p. 2 Graphs.

IL-2-based approaches to Treg enhancement.

Authors: Harris, Ffion Berdugo, Yoana Arroyo Tree, Timothy

Source: Clinical & Experimental Immunology. Feb2023, Vol. 211 Issue 2, p149-163. 15p. 2 Diagrams, 2 Charts.

This result is not displayed to guests.
Login for full access.

Enhancing the Sensitivity of Assays to Detect T Cell Reactivity: The Effect of Cell Separation and Cryopreservation Media.

Authors: TREE, TIMOTHY I.M. ROEP, BART O. PEAKMAN, MARK

Source: Annals of the New York Academy of Sciences. 2004, Vol. 1037 Issue 1, p26-32. 7p.

Subjects: Cryopreservation of organs, tissues, etc., Diabetes, T cells, Diabetic acidosis, Cell separation

Immune modulation in humans: implications for type 1 diabetes mellitus.

Authors: Roep, Bart O. Tree, Timothy I. M.

Source: Nature Reviews Endocrinology. Apr2014, Vol. 10 Issue 4, p229-242. 14p.

Naturally Arising Human CD4 T-Cells That Recognize Islet Autoantigens and Secrete Interleukin-10 Regulate Proinflammatory T-Cell Responses via Linked Suppression.

Authors: Tree, Timothy I. M. Lawson, Jennifer Edwards, Hannah et al.

Source: Diabetes. Jun2010, Vol. 59 Issue 6, p1451-1460. 10p. 1 Black and White Photograph, 1 Diagram, 6 Graphs.

This result is not displayed to guests.
Login for full access.

A Mini Meta-Analysis of Studies on CD4+CD25+ T cells in Human Type 1 Diabetes.

Authors: TREE, TIMOTHY I.M. ROEP, BART O. PEAKMAN, MARK

Source: Annals of the New York Academy of Sciences; 2006, Vol. 1079 Issue 1, p9-18, 10p, 2 Graphs

HLA-DQ-regulated T-cell responses to islet cell autoantigens insulin and GAD65.

Authors: Tree, Timothy I. M. Duinkerken, Gaby Willemen, Sabine et al.

Source: Diabetes. Jul2004, Vol. 53 Issue 7, p1692-1699. 8p. 6 Graphs.

Autoreactive T cell responses show proinflammatory polarization in diabetes but a regulatory phenotype in health.

Authors: Arif, Sefina Tree, Timothy I. Astill, Thomas P. et al.

Source: Journal of Clinical Investigation. Feb2004, Vol. 113 Issue 3, p451-463. 13p. 1 Diagram, 5 Charts, 7 Graphs.

Processing and presentation of the islet autoantigen GAD by vascular endothelial cells promotes transmigration of autoreactive T-cells.

Authors: Greening, James E. Tree, Timothy I.M. Kotowicz, Karolena T. et al.

Source: Diabetes. Mar2003, Vol. 52 Issue 3, p717-725. 9p. 6 Graphs.

Characterization of preparations of GAD65, proinsulin, and the islet tyrosine phosphatase IA-2 for use in detection of autoreactive T-cells in type 1 diabetes: report of phase II of the Second International Immunology of Diabetes Society Workshop for Standardization of T-cell assays in type 1 diabetes.

Authors: Peakman, Mark Tree, Timothy I. Endl, Josef et al.

Source: Diabetes. Aug2001, Vol. 50 Issue 8, p1749-1754. 6p. 2 Charts, 5 Graphs.

HLA Class II molecules on haplotypes associated with type 1 diabetes exhibit similar patterns of binding affinities for coxsackievirus P2C peptides.

Authors: Ellis, Richard J. Varela-Calvino, Ruben Tree, Timothy I. M. et al.

Source: Immunology. Nov2005, Vol. 116 Issue 3, p337-346. 10p. 1 Color Photograph, 2 Diagrams, 1 Chart, 1 Graph.

INNODIA Master Protocol for the evaluation of investigational medicinal products in children, adolescents and adults with newly diagnosed type 1 diabetes.

Authors: Dunger, David B. Bruggraber, Sylvaine F. A. Mander, Adrian P. et al.

Source: Trials. 5/18/2022, Vol. 23 Issue 1, p1-9. 9p. 2 Diagrams, 3 Charts.

The Expression of Active CD11b Monocytes in Blood and Disease Progression in Amyotrophic Lateral Sclerosis.

Authors: Yildiz, Ozlem Schroth, Jonathan Lombardi, Vittoria et al.

Source: International Journal of Molecular Sciences. Mar2022, Vol. 23 Issue 6, p3370-3370. 13p.