Search Results - "Tyler PC"

Allosteric activation unveils protein-mass modulation of ATP phosphoribosyltransferase product release.

Authors: Read, Benjamin J. Mitchell, John B. O. da Silva, Rafael G.

Source: Communications Chemistry. 4/6/2024, Vol. 7, p1-13. 13p.

Rational synthesis of a heparan sulfate saccharide that promotes the activity of BMP2.

Authors: Shaffer KJ Smith RAA Daines AM et al.

Source: Carbohydrate polymers [Carbohydr Polym] 2024 Jun 01; Vol. 333, pp. 121979. Date of Electronic Publication: 2024 Feb 25.

Publication Type: Journal Article

Journal Info: Publisher: Elsevier Applied Science Publishers Country of Publication: England NLM ID: 8307156 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-1344 (Electronic) Linking ISSN: 01448617 NLM ISO Abbreviation: Carbohydr Polym Subsets: MEDLINE

A remarkable change in inhibition potency and selectivity of isofagomine by simple N-modification.

Authors: Culum, André Prasch, Herwig Dorn, Tobias et al.

Source: Chemical Monthly / Monatshefte für Chemie. Jan2025, Vol. 156 Issue 1, p21-34. 14p.

Combined inhibition of MTAP and MAT2a mimics synthetic lethality in tumor models via PRMT5 inhibition.

Authors: Bedard GT Gilaj N Peregrina K et al.

Source: The Journal of biological chemistry [J Biol Chem] 2024 Jan; Vol. 300 (1), pp. 105492. Date of Electronic Publication: 2023 Nov 23.

Publication Type: Journal Article; Research Support, N.I.H., Extramural

Journal Info: Publisher: Elsevier Inc. on behalf of American Society for Biochemistry and Molecular Biology Country of Publication: United States NLM ID: 2985121R Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1083-351X (Electronic) Linking ISSN: 00219258 NLM ISO Abbreviation: J Biol Chem Subsets: MEDLINE

Enhancing BMP-2-mediated osteogenesis with a synthetic heparan sulfate mimetic.

Authors: Smith RAA Luo X Lu X et al.

Source: Biomaterials advances [Biomater Adv] 2023 Oct 24; Vol. 155, pp. 213671. Date of Electronic Publication: 2023 Oct 24.

Publication Type: Journal Article

Journal Info: Publisher: Elsevier B.V Country of Publication: Netherlands NLM ID: 9918383886206676 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2772-9508 (Electronic) Linking ISSN: 27729508 NLM ISO Abbreviation: Biomater Adv Subsets: MEDLINE

Uncertainty in protein–ligand binding constants: asymmetric confidence intervals versus standard errors.

Authors: Paketurytė, Vaida Petrauskas, Vytautas Zubrienė, Asta et al.

Source: European Biophysics Journal. May2021, Vol. 50 Issue 3/4, p661-670. 10p.

Biofilm formation and inhibition mediated by bacterial quorum sensing.

Authors: Wang, Yingsong Bian, Zeran Wang, Yan

Source: Applied Microbiology & Biotechnology; Oct2022, Vol. 106 Issue 19/20, p6365-6381, 17p

Recent advances in adamantane-linked heterocycles: synthesis and biological activity.

Authors: Helal MH Abusaif MS Ragab A et al.

Source: Molecular diversity [Mol Divers] 2026 Jun; Vol. 30 (3), pp. 3471-3519. Date of Electronic Publication: 2025 Nov 21.

Publication Type: Journal Article; Review

Journal Info: Publisher: ESCOM Science Publishers Country of Publication: Netherlands NLM ID: 9516534 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1573-501X (Electronic) Linking ISSN: 13811991 NLM ISO Abbreviation: Mol Divers Subsets: MEDLINE

Recent analytical advances in the detection and characterization of 3-O-sulfated heparan sulfate.

Authors: Mernie, Elias Zaia, Joseph

Source: Analytical & Bioanalytical Chemistry. Jul2025, Vol. 417 Issue 16, p3551-3562. 12p.

Heparanase inhibition as a systemic approach to protect the endothelial glycocalyx and prevent microvascular complications in diabetes.

Authors: Gamez, Monica Elhegni, Hesham E. Fawaz, Sarah et al.

Source: Cardiovascular Diabetology. 2/1/2024, Vol. 23 Issue 1, p1-17. 17p.

The novel HS-mimetic, Tet-29, regulates immune cell trafficking across barriers of the CNS during inflammation.

Authors: Peck, Tessa Davis, Connor Lenihan-Geels, Georgia et al.

Source: Journal of Neuroinflammation. 11/1/2023, Vol. 20 Issue 1, p1-16. 16p.

The design of protozoan phosphoribosyltransferase inhibitors containing non-charged phosphate mimic residues.

Authors: Gai S Suthagar K Shaffer KJ et al.

Source: Bioorganic & medicinal chemistry [Bioorg Med Chem] 2022 Nov 15; Vol. 74, pp. 117038. Date of Electronic Publication: 2022 Sep 28.

Publication Type: Journal Article; Research Support, N.I.H., Extramural

Journal Info: Publisher: Elsevier Science Country of Publication: England NLM ID: 9413298 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1464-3391 (Electronic) Linking ISSN: 09680896 NLM ISO Abbreviation: Bioorg Med Chem Subsets: MEDLINE

Binding thermodynamics and interaction patterns of human purine nucleoside phosphorylase-inhibitor complexes from extensive free energy calculations.

Authors: Huai, Zhe Yang, Huaiyu Sun, Zhaoxi

Source: Journal of Computer-Aided Molecular Design; May2021, Vol. 35 Issue 5, p643-656, 14p

Helicobacter pylori treatment in the post-antibiotics era—searching for new drug targets.

Authors: Roszczenko-Jasińska, Paula Wojtyś, Marta Ilona Jagusztyn-Krynicka, Elżbieta K.

Source: Applied Microbiology & Biotechnology; Dec2020, Vol. 104 Issue 23, p9891-9905, 15p

Extreme enthalpy‒entropy compensation in the dimerization of small solutes in aqueous solution.

Authors: Scott, David J. Winzor, Donald J.

Source: European Biophysics Journal. Nov2024, Vol. 53 Issue 7/8, p373-384. 12p.

High rates of antibiotic resistance and biofilm production in Escherichia coli isolates from food products of animal and vegetable origins in Tunisia: a real threat to human health.

Authors: Badi, Souhir Salah Abbassi, Mohamed Snoussi, Mejdi et al.

Source: International Journal of Environmental Health Research. Feb 2022, Vol. 32 Issue 2, p406-416. 11p. 2 Charts, 2 Graphs.

Malaria parasite cysteine and aspartic proteases as key drug targets for antimalarial therapy.

Authors: Adeoye AO Lobb KA

Source: Journal of molecular modeling [J Mol Model] 2025 Feb 08; Vol. 31 (3), pp. 78. Date of Electronic Publication: 2025 Feb 08.

Publication Type: Journal Article; Review

Journal Info: Publisher: Springer Country of Publication: Germany NLM ID: 9806569 Publication Model: Electronic Cited Medium: Internet ISSN: 0948-5023 (Electronic) Linking ISSN: 09485023 NLM ISO Abbreviation: J Mol Model Subsets: MEDLINE

In Vitro and in Vivo Therapeutic Evaluation of Ethanolic Extract of Sumac and Compounds of Linalool and Eugenol Against Localized Cutaneous Leishmaniasis Induced by Leishmania major.

Authors: Aval SA Heidari A Mohebali M et al.

Source: Acta parasitologica [Acta Parasitol] 2025 Dec 16; Vol. 71 (1), pp. 7. Date of Electronic Publication: 2025 Dec 16.

Publication Type: Journal Article

Journal Info: Publisher: Springer International Publishing Country of Publication: Switzerland NLM ID: 9301947 Publication Model: Electronic Cited Medium: Internet ISSN: 1896-1851 (Electronic) Linking ISSN: 12302821 NLM ISO Abbreviation: Acta Parasitol Subsets: MEDLINE

Single-base resolution quantitative genome methylation analysis in the model bacterium Helicobacter pylori by enzymatic methyl sequencing (EM-Seq) reveals influence of strain, growth phase, and methyl homeostasis.

Authors: Patel, Lubna Ailloud, Florent Suerbaum, Sebastian et al.

Source: BMC Biology. 5/28/2024, Vol. 22 Issue 1, p1-22. 22p.

Exploring optimal drug targets through subtractive proteomics analysis and pangenomic insights for tailored drug design in tuberculosis.

Authors: Khan, Muhammad Fayaz Ali, Amjad Rehman, Hafiz Muzzammel et al.

Source: Scientific Reports. 5/13/2024, Vol. 14 Issue 1, p1-24. 24p.