Search Results - "Watari, R."

Coactivation of distal muscles in neuropathic diabetic patients during gait

Authors: Akashi, P.M.H. Watari, R. Suda, E.Y. et al.

Source: Journal of Biomechanics. Dec2006 Supplement 1, Vol. 39, pS111-S111. 1p.

Predictive effects of diabetes-related risk factors for falls in community-dwelling people with diabetic peripheral neuropathy based on a logistic regression model.

Authors: Suda EY Sartor CD Passaro AC et al.

Source: PloS one [PLoS One] 2026 Jan 02; Vol. 21 (1), pp. e0340262. Date of Electronic Publication: 2026 Jan 02 (Print Publication: 2026).

Publication Type: Journal Article

Journal Info: Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection Cited Medium: Internet ISSN: 1932-6203 (Electronic) Linking ISSN: 19326203 NLM ISO Abbreviation: PLoS One Subsets: MEDLINE

Evaluation of OATP1B inhibitory potential using an endogenous biomarker coproporphyrin-I in new drug applications: Case reports submitted by 2024.

Authors: Watari R; Laboratory for Drug Discovery and Development, Shionogi & Co., Ltd, Japan. Electronic address: ryosuke.watari@shionogi.co.jp.

Source: Drug metabolism and pharmacokinetics [Drug Metab Pharmacokinet] 2026 Feb; Vol. 66, pp. 101513. Date of Electronic Publication: 2025 Dec 17.

Publication Type: Journal Article; Review

Journal Info: Publisher: Elsevier Country of Publication: England NLM ID: 101164773 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1880-0920 (Electronic) Linking ISSN: 13474367 NLM ISO Abbreviation: Drug Metab Pharmacokinet Subsets: MEDLINE

Selection of Solubility Enhancement Technologies for S-892216, a Novel COVID-19 Drug Candidate.

Authors: Ohashi R Otake S Murata T et al.

Source: Pharmaceutics [Pharmaceutics] 2025 Dec 18; Vol. 17 (12). Date of Electronic Publication: 2025 Dec 18.

Publication Type: Journal Article

Journal Info: Publisher: MDPI Country of Publication: Switzerland NLM ID: 101534003 Publication Model: Electronic Cited Medium: Print ISSN: 1999-4923 (Print) Linking ISSN: 19994923 NLM ISO Abbreviation: Pharmaceutics Subsets: PubMed not MEDLINE

Discovery of the Clinical Candidate S-892216: A Second-Generation of SARS-CoV-2 3CL Protease Inhibitor for Treating COVID-19.

Authors: Unoh Y Hirai K Uehara S et al.

Source: Journal of medicinal chemistry [J Med Chem] 2025 Oct 23; Vol. 68 (20), pp. 21099-21119. Date of Electronic Publication: 2025 Jul 05.

Publication Type: Journal Article

Journal Info: Publisher: American Chemical Society Country of Publication: United States NLM ID: 9716531 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1520-4804 (Electronic) Linking ISSN: 00222623 NLM ISO Abbreviation: J Med Chem Subsets: MEDLINE

Investigation of an OATP1B inhibitory effect by a cyclic peptide using the endogenous biomarker coproporphyrin-I in monkeys.

Authors: Sawada H Kido Y Iwasaki M et al.

Source: Drug metabolism and pharmacokinetics [Drug Metab Pharmacokinet] 2025 Aug; Vol. 63, pp. 101497. Date of Electronic Publication: 2025 Jun 03.

Publication Type: Journal Article

Journal Info: Publisher: Elsevier Country of Publication: England NLM ID: 101164773 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1880-0920 (Electronic) Linking ISSN: 13474367 NLM ISO Abbreviation: Drug Metab Pharmacokinet Subsets: MEDLINE

Efficacy comparison of 3CL protease inhibitors ensitrelvir and nirmatrelvir against SARS-CoV-2 in vitro and in vivo.

Authors: Kuroda T Nobori H Fukao K et al.

Source: The Journal of antimicrobial chemotherapy [J Antimicrob Chemother] 2023 Apr 03; Vol. 78 (4), pp. 946-952.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Oxford University Press Country of Publication: England NLM ID: 7513617 Publication Model: Print Cited Medium: Internet ISSN: 1460-2091 (Electronic) Linking ISSN: 03057453 NLM ISO Abbreviation: J Antimicrob Chemother Subsets: MEDLINE

In vivo production of engineered ACE2 decoy protects lungs from SARS-CoV-2 infection.

Authors: Suzuki Y Miyazaki T Ida Y et al.

Source: Molecular therapy. Nucleic acids [Mol Ther Nucleic Acids] 2025 Jan 29; Vol. 36 (1), pp. 102467. Date of Electronic Publication: 2025 Jan 29 (Print Publication: 2025).

Publication Type: Journal Article

Journal Info: Publisher: Cell Press Country of Publication: United States NLM ID: 101581621 Publication Model: eCollection Cited Medium: Print ISSN: 2162-2531 (Print) Linking ISSN: 21622531 NLM ISO Abbreviation: Mol Ther Nucleic Acids Subsets: PubMed not MEDLINE

Novel Approach to Pre-Exposure Prophylaxis (PrEP) of COVID-19: Development of S-892216 Long-Acting Injectable Suspension.

Authors: Ohashi R Watari R Kondo D et al.

Source: Chemical & pharmaceutical bulletin [Chem Pharm Bull (Tokyo)] 2025; Vol. 73 (8), pp. 670-677.

Publication Type: Journal Article

Journal Info: Publisher: Pharmaceutical Society of Japan Country of Publication: Japan NLM ID: 0377775 Publication Model: Print Cited Medium: Internet ISSN: 1347-5223 (Electronic) Linking ISSN: 00092363 NLM ISO Abbreviation: Chem Pharm Bull (Tokyo) Subsets: MEDLINE

Quantitative prediction of OATP1B-mediated drug-drug interactions using endogenous biomarker coproporphyrin I.

Authors: Takubo H Bessho K Watari R et al.

Source: Xenobiotica; the fate of foreign compounds in biological systems [Xenobiotica] 2022 Apr; Vol. 52 (4), pp. 397-404. Date of Electronic Publication: 2022 Jun 14.

Publication Type: Journal Article

Journal Info: Publisher: Informa Healthcare Country of Publication: England NLM ID: 1306665 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1366-5928 (Electronic) Linking ISSN: 00498254 NLM ISO Abbreviation: Xenobiotica Subsets: MEDLINE

Predictive Effect of Well-Known Risk Factors and Foot-Core Training in Lower Limb Running-Related Injuries in Recreational Runners: A Secondary Analysis of a Randomized Controlled Trial.

Authors: Suda EY Watari R Matias AB et al.

Source: The American journal of sports medicine [Am J Sports Med] 2022 Jan; Vol. 50 (1), pp. 248-254. Date of Electronic Publication: 2021 Nov 17.

Publication Type: Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Sage Publications Country of Publication: United States NLM ID: 7609541 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1552-3365 (Electronic) Linking ISSN: 03635465 NLM ISO Abbreviation: Am J Sports Med Subsets: MEDLINE

Minimal Involvement of P-gp and BCRP in Oral Absorption of Ensitrelvir, An Oral SARS-CoV-2 3C-like Protease Inhibitor, in a Non-Clinical Investigation.

Authors: Watari R Tamura N Yoshida S et al.

Source: Journal of pharmaceutical sciences [J Pharm Sci] 2024 Sep; Vol. 113 (9), pp. 2871-2878. Date of Electronic Publication: 2024 Jun 15.

Publication Type: Journal Article

Journal Info: Publisher: Elsevier Country of Publication: United States NLM ID: 2985195R Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1520-6017 (Electronic) Linking ISSN: 00223549 NLM ISO Abbreviation: J Pharm Sci Subsets: MEDLINE

Prediction of drug-drug interaction risk of P-glycoprotein substrate in drug discovery.

Authors: Kido Y Nanchi I Matsuzaki T et al.

Source: Drug metabolism and pharmacokinetics [Drug Metab Pharmacokinet] 2024 Jun; Vol. 56, pp. 101008. Date of Electronic Publication: 2024 Mar 11.

Publication Type: Journal Article

Journal Info: Publisher: Elsevier Country of Publication: England NLM ID: 101164773 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1880-0920 (Electronic) Linking ISSN: 13474367 NLM ISO Abbreviation: Drug Metab Pharmacokinet Subsets: MEDLINE

Prophylactic effect of ensitrelvir in mice infected with SARS-CoV-2.

Authors: Nobori H Baba K Kuroda T et al.

Source: Antiviral research [Antiviral Res] 2024 Apr; Vol. 224, pp. 105852. Date of Electronic Publication: 2024 Feb 28.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Elsevier Country of Publication: Netherlands NLM ID: 8109699 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1872-9096 (Electronic) Linking ISSN: 01663542 NLM ISO Abbreviation: Antiviral Res Subsets: MEDLINE

Utility of Coproporphyrin-I Determination in First-in-Human Study for Early Evaluation of OATP1B Inhibitory Potential Based on Investigation of Ensitrelvir, an Oral SARS-CoV-2 3C-Like Protease Inhibitor.

Authors: Watari R Sawada H Hashimoto H et al.

Source: Journal of pharmaceutical sciences [J Pharm Sci] 2024 Mar; Vol. 113 (3), pp. 798-805. Date of Electronic Publication: 2023 Sep 23.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Elsevier Country of Publication: United States NLM ID: 2985195R Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1520-6017 (Electronic) Linking ISSN: 00223549 NLM ISO Abbreviation: J Pharm Sci Subsets: MEDLINE

Effects of a foot-ankle muscle strengthening program on pain and function in individuals with knee osteoarthritis: a randomized controlled trial.

Authors: Dantas GAF Sacco ICN Ferrari AV et al.

Source: Brazilian journal of physical therapy [Braz J Phys Ther] 2023 Jul-Aug; Vol. 27 (4), pp. 100531. Date of Electronic Publication: 2023 Aug 11.

Publication Type: Randomized Controlled Trial; Journal Article

Journal Info: Publisher: Elsevier B.V Country of Publication: Brazil NLM ID: 101615124 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1809-9246 (Electronic) Linking ISSN: 14133555 NLM ISO Abbreviation: Braz J Phys Ther Subsets: MEDLINE

Automated Accelerometer-Based Gait Event Detection During Multiple Running Conditions.

Authors: Benson LC Clermont CA Watari R et al.

Source: Sensors (Basel, Switzerland) [Sensors (Basel)] 2019 Mar 27; Vol. 19 (7). Date of Electronic Publication: 2019 Mar 27.

Publication Type: Journal Article

Journal Info: Publisher: MDPI Country of Publication: Switzerland NLM ID: 101204366 Publication Model: Electronic Cited Medium: Internet ISSN: 1424-8220 (Electronic) Linking ISSN: 14248220 NLM ISO Abbreviation: Sensors (Basel) Subsets: PubMed not MEDLINE

Design and lyophilization of lipid nanoparticles for mRNA vaccine and its robust immune response in mice and nonhuman primates.

Authors: Suzuki Y Miyazaki T Muto H et al.

Source: Molecular therapy. Nucleic acids [Mol Ther Nucleic Acids] 2022 Dec 13; Vol. 30, pp. 226-240. Date of Electronic Publication: 2022 Sep 24.

Publication Type: Journal Article

Journal Info: Publisher: Cell Press Country of Publication: United States NLM ID: 101581621 Publication Model: Print-Electronic Cited Medium: Print ISSN: 2162-2531 (Print) Linking ISSN: 21622531 NLM ISO Abbreviation: Mol Ther Nucleic Acids Subsets: PubMed not MEDLINE

Runners with patellofemoral pain demonstrate sub-groups of pelvic acceleration profiles using hierarchical cluster analysis: an exploratory cross-sectional study.

Authors: Watari R Osis ST Phinyomark A et al.

Source: BMC musculoskeletal disorders [BMC Musculoskelet Disord] 2018 Apr 19; Vol. 19 (1), pp. 120. Date of Electronic Publication: 2018 Apr 19.

Publication Type: Journal Article

Journal Info: Publisher: BioMed Central Country of Publication: England NLM ID: 100968565 Publication Model: Electronic Cited Medium: Internet ISSN: 1471-2474 (Electronic) Linking ISSN: 14712474 NLM ISO Abbreviation: BMC Musculoskelet Disord Subsets: MEDLINE

A long-term culture system based on a collagen vitrigel membrane chamber that supports liver-specific functions of hepatocytes isolated from mice with humanized livers.

Authors: Watari R Kakiki M Oshikata A et al.

Source: The Journal of toxicological sciences [J Toxicol Sci] 2018; Vol. 43 (8), pp. 521-529.

Publication Type: Journal Article

Journal Info: Publisher: Doku Sayō Kenkyūkai Country of Publication: Japan NLM ID: 7805798 Publication Model: Print Cited Medium: Internet ISSN: 1880-3989 (Electronic) Linking ISSN: 03881350 NLM ISO Abbreviation: J Toxicol Sci Subsets: MEDLINE