Search Results - "Weekes, Daniel"

The SUMO modification pathway is involved in the BRCA1 response to genotoxic stress.

Authors: Morris, Joanna R. Boutell, Chris Keppler, Melanie et al.

Source: Nature. 12/17/2009, Vol. 462 Issue 7275, p886-890. 5p. 4 Graphs.

Subjects: Genetic toxicology, BRCA genes, Tumor suppressor genes, DNA damage, Breast cancer, Ovarian cancer, Ubiquitin, Ligases, Enzymes

Sirtuin inhibition is synthetic lethal with BRCA1 or BRCA2 deficiency.

Authors: Bajrami, Ilirjana Walker, Callum Krastev, Dragomir B. et al.

Source: Communications Biology. 11/8/2021, Vol. 4 Issue 1, p1-16. 16p.

Analysis of the interaction between the Ret finger protein and the retinoblastoma protein

Authors: Weekes, Daniel Beckford

URL: http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.428040

Selective Ablation of Retinoblastoma Protein Function by the RET Finger Protein

Authors: Krützfeldt, Maja Ellis, Mark Weekes, Daniel B. et al.

Source: Molecular Cell. Apr2005, Vol. 18 Issue 2, p213-224. 12p.

The proteasomal de-ubiquitinating enzyme POH1 promotes the double-strand DNA break response.

Authors: Butler, Laura R Densham, Ruth M Jia, Junying et al.

Source: EMBO Journal. 10/3/2012, Vol. 31 Issue 19, p3918-3934. 17p. 1 Diagram, 9 Graphs.

Tumour specific HORMAD1 expression perturbs mitotic arrest and drives sensitivity to mitotic kinase inhibitors.

Authors: Walker C Kollarovic G Weekes D et al.

Source: Nature communications [Nat Commun] 2026 Mar 11; Vol. 17 (1). Date of Electronic Publication: 2026 Mar 11.

Publication Type: Journal Article

Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE

Integrated genomics and functional validation identifies malignant cell specific dependencies in triple negative breast cancer.

Authors: Patel N Weekes D Drosopoulos K et al.

Source: Nature communications [Nat Commun] 2018 Mar 13; Vol. 9 (1), pp. 1044. Date of Electronic Publication: 2018 Mar 13.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE

Functional screening reveals HORMAD1-driven gene dependencies associated with translesion synthesis and replication stress tolerance.

Authors: Tarantino D Walker C Weekes D et al.

Source: Oncogene [Oncogene] 2022 Aug; Vol. 41 (32), pp. 3969-3977. Date of Electronic Publication: 2022 Jun 29.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 8711562 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-5594 (Electronic) Linking ISSN: 09509232 NLM ISO Abbreviation: Oncogene Subsets: MEDLINE

The ubiquitin-dependent ATPase p97 removes cytotoxic trapped PARP1 from chromatin.

Authors: Krastev DB Li S Sun Y et al.

Source: Nature cell biology [Nat Cell Biol] 2022 Jan; Vol. 24 (1), pp. 62-73. Date of Electronic Publication: 2022 Jan 10.

Publication Type: Journal Article; Research Support, N.I.H., Intramural; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Macmillan Magazines Ltd Country of Publication: England NLM ID: 100890575 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-4679 (Electronic) Linking ISSN: 14657392 NLM ISO Abbreviation: Nat Cell Biol Subsets: MEDLINE

The deSUMOylase SENP7 promotes chromatin relaxation for homologous recombination DNA repair.

Authors: Garvin AJ Densham RM Blair-Reid SA et al.

Source: EMBO reports [EMBO Rep] 2013 Nov; Vol. 14 (11), pp. 975-83. Date of Electronic Publication: 2013 Sep 10.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 100963049 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1469-3178 (Electronic) Linking ISSN: 1469221X NLM ISO Abbreviation: EMBO Rep Subsets: MEDLINE

Genomic Complexity Profiling Reveals That HORMAD1 Overexpression Contributes to Homologous Recombination Deficiency in Triple-Negative Breast Cancers.

Authors: Watkins J Weekes D Shah V et al.

Source: Cancer discovery [Cancer Discov] 2015 May; Vol. 5 (5), pp. 488-505. Date of Electronic Publication: 2015 Mar 13.

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

Journal Info: Publisher: American Association for Cancer Research Country of Publication: United States NLM ID: 101561693 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2159-8290 (Electronic) Linking ISSN: 21598274 NLM ISO Abbreviation: Cancer Discov Subsets: MEDLINE

Attenuation of disease phenotype through alternative translation initiation in low-penetrance retinoblastoma.

Authors: Sánchez-Sánchez F Ramírez-Castillejo C Weekes DB et al.

Source: Human mutation [Hum Mutat] 2007 Feb; Vol. 28 (2), pp. 159-67.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Wiley-Liss Country of Publication: United States NLM ID: 9215429 Publication Model: Print Cited Medium: Internet ISSN: 1098-1004 (Electronic) Linking ISSN: 10597794 NLM ISO Abbreviation: Hum Mutat Subsets: MEDLINE