Glyphosate biomonitoring for farmers and their families: results from the Farm Family Exposure Study.
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| Title: | Glyphosate biomonitoring for farmers and their families: results from the Farm Family Exposure Study. |
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| Authors: | Acquavella JF (AUTHOR), Alexander BH (AUTHOR), Mandel JS (AUTHOR), Gustin C (AUTHOR), Baker B (AUTHOR), Chapman P (AUTHOR), Bleeke M (AUTHOR) |
| Source: | Environmental Health Perspectives. Mar2004, Vol. 112 Issue 3, p321-326. 6p. |
| Abstract: | Glyphosate is the active ingredient in Roundup agricultural herbicides and other herbicide formulations that are widely used for agricultural, forestry, and residential weed control. As part of the Farm Family Exposure Study, we evaluated urinary glyphosate concentrations for 48 farmers, their spouses, and their 79 children (4-18 years of age). We evaluated 24-hr composite urine samples for each family member the day before, the day of, and for 3 days after a glyphosate application. Sixty percent of farmers had detectable levels of glyphosate in their urine on the day of application. The geometric mean (GM) concentration was 3 ppb, the maximum value was 233 ppb, and the highest estimated systemic dose was 0.004 mg/kg. Farmers who did not use rubber gloves had higher GM urinary concentrations than did other farmers (10 ppb vs. 2.0 ppb). For spouses, 4% had detectable levels in their urine on the day of application. Their maximum value was 3 ppb. For children, 12% had detectable glyphosate in their urine on the day of application, with a maximum concentration of 29 ppb. All but one of the children with detectable concentrations had helped with the application or were present during herbicide mixing, loading, or application. None of the systemic doses estimated in this study approached the U.S. Environmental Protection Agency reference dose for glyphosate of 2 mg/kg/day. Nonetheless, it is advisable to minimize exposure to pesticides, and this study did identify specific practices that could be modified to reduce the potential for exposure. [ABSTRACT FROM AUTHOR] |
| Copyright of Environmental Health Perspectives is the property of National Institute of Environmental Health Sciences and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.) | |
| URL: | 12676868 |
| Database: | GreenFILE |
| FullText | Links: – Type: pdflink Text: Availability: 0 |
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| Header | DbId: 8gh DbLabel: GreenFILE An: 106559519 AccessLevel: 6 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: Glyphosate biomonitoring for farmers and their families: results from the Farm Family Exposure Study. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AR" term="%22Acquavella+JF%22">Acquavella JF</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Alexander+BH%22">Alexander BH</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Mandel+JS%22">Mandel JS</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Gustin+C%22">Gustin C</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Baker+B%22">Baker B</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Chapman+P%22">Chapman P</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Bleeke+M%22">Bleeke M</searchLink> (AUTHOR) – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%22Environmental+Health+Perspectives%22">Environmental Health Perspectives</searchLink>. Mar2004, Vol. 112 Issue 3, p321-326. 6p. – Name: Abstract Label: Abstract Group: Ab Data: Glyphosate is the active ingredient in Roundup agricultural herbicides and other herbicide formulations that are widely used for agricultural, forestry, and residential weed control. As part of the Farm Family Exposure Study, we evaluated urinary glyphosate concentrations for 48 farmers, their spouses, and their 79 children (4-18 years of age). We evaluated 24-hr composite urine samples for each family member the day before, the day of, and for 3 days after a glyphosate application. Sixty percent of farmers had detectable levels of glyphosate in their urine on the day of application. The geometric mean (GM) concentration was 3 ppb, the maximum value was 233 ppb, and the highest estimated systemic dose was 0.004 mg/kg. Farmers who did not use rubber gloves had higher GM urinary concentrations than did other farmers (10 ppb vs. 2.0 ppb). For spouses, 4% had detectable levels in their urine on the day of application. Their maximum value was 3 ppb. For children, 12% had detectable glyphosate in their urine on the day of application, with a maximum concentration of 29 ppb. All but one of the children with detectable concentrations had helped with the application or were present during herbicide mixing, loading, or application. None of the systemic doses estimated in this study approached the U.S. Environmental Protection Agency reference dose for glyphosate of 2 mg/kg/day. Nonetheless, it is advisable to minimize exposure to pesticides, and this study did identify specific practices that could be modified to reduce the potential for exposure. [ABSTRACT FROM AUTHOR] – Name: AbstractSuppliedCopyright Label: Group: Ab Data: <i>Copyright of Environmental Health Perspectives is the property of National Institute of Environmental Health Sciences and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.) – Name: URL Label: URL Group: URL Data: <link linkTarget="URL" linkTerm="12676868" linkWindow="_blank">12676868</link> |
| PLink | https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=8gh&AN=106559519 |
| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1289/ehp.6667 Languages: – Code: eng Text: English PhysicalDescription: Pagination: PageCount: 6 StartPage: 321 Titles: – TitleFull: Glyphosate biomonitoring for farmers and their families: results from the Farm Family Exposure Study. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Acquavella JF – PersonEntity: Name: NameFull: Alexander BH – PersonEntity: Name: NameFull: Mandel JS – PersonEntity: Name: NameFull: Gustin C – PersonEntity: Name: NameFull: Baker B – PersonEntity: Name: NameFull: Chapman P – PersonEntity: Name: NameFull: Bleeke M IsPartOfRelationships: – BibEntity: Dates: – D: 01 M: 03 Text: Mar2004 Type: published Y: 2004 Identifiers: – Type: issn-print Value: 00916765 Numbering: – Type: volume Value: 112 – Type: issue Value: 3 Titles: – TitleFull: Environmental Health Perspectives Type: main |
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