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Sulfated Polysaccharides from Tunisian Fish Skins: Antioxidant, DNA Damage Protective Effect and Antihypertensive Activities.

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Title: Sulfated Polysaccharides from Tunisian Fish Skins: Antioxidant, DNA Damage Protective Effect and Antihypertensive Activities.
Authors: Krichen, Fatma1, Karaoud, Wafa1, Sayari, Nadhem1, Sila, Assaâd, Kallel, Fatma1, Ellouz-Chaabouni, Semia, Bougatef, Ali ali.bougatef79@gmail.com
Source: Journal of Polymers & the Environment. Jun2016, Vol. 24 Issue 2, p166-175. 10p.
Subject Terms: Polysaccharides, Surface morphology, Balistidae, Carotenes
Abstract: Sulfated polysaccharides were isolated from two Tunisian fish skins grey triggerfish ( Balistes capriscus) (GTSP) and smooth hound ( Mustelus mustelus) (SHSP). Their chemical and physical characteristics were investigated. The Analysis of surface morphology by scanning electron microscopy of both sulfated polysaccharides displayed the same shape with netted structure. The antioxidant activities of GTSP and SHSP were evaluated using various in vitro antioxidant assays: 1,1-diphenyl-2-picrylhydrazyl (DPPH) radical-scavenging activity, reducing power, β-carotene bleaching inhibition assay (IC = 0.5 mg mL and IC = 0.6 mg mL) and DNA nicking assay. Both sulfated polysaccharides exhibited good antioxidant activities. The sulfated polysaccharides showed strong angiotensin I-converting enzyme inhibitory activities (IC = 0.16 mg mL and IC = 0.18 mg mL). These results revealed that GTSP and SHSP exhibited significant antihypertensive activities. Overall, the results indicated that grey triggerfish and smooth hound skins can be used to generate high value-added products, thus offering a valuable source of bioactive sulfated polysaccharides for application in wide range of biotechnological applications. [ABSTRACT FROM AUTHOR]
Copyright of Journal of Polymers & the Environment is the property of Springer Nature and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
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  Data: Sulfated Polysaccharides from Tunisian Fish Skins: Antioxidant, DNA Damage Protective Effect and Antihypertensive Activities.
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  Data: <searchLink fieldCode="JN" term="%22Journal+of+Polymers+%26+the+Environment%22">Journal of Polymers & the Environment</searchLink>. Jun2016, Vol. 24 Issue 2, p166-175. 10p.
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  Data: Sulfated polysaccharides were isolated from two Tunisian fish skins grey triggerfish ( Balistes capriscus) (GTSP) and smooth hound ( Mustelus mustelus) (SHSP). Their chemical and physical characteristics were investigated. The Analysis of surface morphology by scanning electron microscopy of both sulfated polysaccharides displayed the same shape with netted structure. The antioxidant activities of GTSP and SHSP were evaluated using various in vitro antioxidant assays: 1,1-diphenyl-2-picrylhydrazyl (DPPH) radical-scavenging activity, reducing power, β-carotene bleaching inhibition assay (IC = 0.5 mg mL and IC = 0.6 mg mL) and DNA nicking assay. Both sulfated polysaccharides exhibited good antioxidant activities. The sulfated polysaccharides showed strong angiotensin I-converting enzyme inhibitory activities (IC = 0.16 mg mL and IC = 0.18 mg mL). These results revealed that GTSP and SHSP exhibited significant antihypertensive activities. Overall, the results indicated that grey triggerfish and smooth hound skins can be used to generate high value-added products, thus offering a valuable source of bioactive sulfated polysaccharides for application in wide range of biotechnological applications. [ABSTRACT FROM AUTHOR]
– Name: AbstractSuppliedCopyright
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  Data: <i>Copyright of Journal of Polymers & the Environment is the property of Springer Nature and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.)
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        Value: 10.1007/s10924-016-0759-6
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        Text: English
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      – SubjectFull: Surface morphology
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              Text: Jun2016
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