Nonfat milk attenuates acute hyperglycemia in individuals with android obesity: A randomized control trial.
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| Title: | Nonfat milk attenuates acute hyperglycemia in individuals with android obesity: A randomized control trial. |
|---|---|
| Authors: | Leary, Miriam P.1, Roy, Stephen J.1, Lim, Jisok1, Park, Wonil1, Ferrari, Rodrigo1, Eaves, Jared1, Machin, Daniel R.1, Tanaka, Hirofumi1 |
| Source: | Food Science & Nutrition. Nov2018, Vol. 6 Issue 8, p2104-2112. 9p. |
| Subject Terms: | Hyperglycemia, Obesity, Randomized controlled trials, Glucose tolerance tests, Fat content of milk |
| Abstract: | Background: Elevated android body fat increases the risk of developing cardiometabolic diseases. Postprandial hyperglycemia contributes to the proatherogenic metabolic state evident in android adiposity. Due to the insulinotropic effect of milk‐derived proteins, postprandial hyperglycemia has been shown to be reduced with the addition of dairy products. The purpose of this study was to determine whether one serving of nonfat milk added to an oral glucose tolerance test (OGTT) could attenuate postprandial hyperglycemia in individuals with elevated android adiposity and whether these improvements would be associated with metabolic and/or peripheral hemodynamic effects. Methods: In this placebo‐controlled, randomized, crossover experimental study, 29 overweight/obese adults (26 ± 1 year) consumed an OGTT beverage (75 g glucose) combined with either nonfat milk (227 g) or a placebo control (12 g lactose + 8 g protein + 207 g water) that was matched for both carbohydrate and protein quantities. Results: In the whole sample, blood glucose and insulin concentrations increased over time in both trials with no significant differences between trials. Relative increases in peak blood glucose response were significantly related to android body fat (p < 0.05). The subjects in the highest tertiles of android body fat displayed attenuated hyperglycemic responses as well as improvements in flow‐mediated dilation (FMD) after milk intake. Conclusions: A single serving of nonfat milk may attenuate acute hyperglycemia in individuals with elevated android body fat offering a simple and convenient option for managing elevations in blood glucose. Due to the insulinotropic effect of milk‐derived proteins, postprandial hyperglycemia has been shown to be reduced with the addition of dairy products. The purpose of this study was to determine whether one serving of nonfat milk added to an oral glucose tolerance test (OGTT) could attenuate postprandial hyperglycemia in individuals with elevated android adiposity and whether these improvements would be associated with metabolic and/or peripheral hemodynamic effects. The subjects in the highest tertiles of android body fat displayed attenuated hyperglycemic responses as well as improvements in FMD after milk intake. [ABSTRACT FROM AUTHOR] |
| Copyright of Food Science & Nutrition is the property of Wiley-Blackwell and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.) | |
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| Header | DbId: 8gh DbLabel: GreenFILE An: 133261056 AccessLevel: 6 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: Nonfat milk attenuates acute hyperglycemia in individuals with android obesity: A randomized control trial. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AR" term="%22Leary%2C+Miriam+P%2E%22">Leary, Miriam P.</searchLink><relatesTo>1</relatesTo><br /><searchLink fieldCode="AR" term="%22Roy%2C+Stephen+J%2E%22">Roy, Stephen J.</searchLink><relatesTo>1</relatesTo><br /><searchLink fieldCode="AR" term="%22Lim%2C+Jisok%22">Lim, Jisok</searchLink><relatesTo>1</relatesTo><br /><searchLink fieldCode="AR" term="%22Park%2C+Wonil%22">Park, Wonil</searchLink><relatesTo>1</relatesTo><br /><searchLink fieldCode="AR" term="%22Ferrari%2C+Rodrigo%22">Ferrari, Rodrigo</searchLink><relatesTo>1</relatesTo><br /><searchLink fieldCode="AR" term="%22Eaves%2C+Jared%22">Eaves, Jared</searchLink><relatesTo>1</relatesTo><br /><searchLink fieldCode="AR" term="%22Machin%2C+Daniel+R%2E%22">Machin, Daniel R.</searchLink><relatesTo>1</relatesTo><br /><searchLink fieldCode="AR" term="%22Tanaka%2C+Hirofumi%22">Tanaka, Hirofumi</searchLink><relatesTo>1</relatesTo> – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%22Food+Science+%26+Nutrition%22">Food Science & Nutrition</searchLink>. Nov2018, Vol. 6 Issue 8, p2104-2112. 9p. – Name: Subject Label: Subject Terms Group: Su Data: <searchLink fieldCode="DE" term="%22Hyperglycemia%22">Hyperglycemia</searchLink><br /><searchLink fieldCode="DE" term="%22Obesity%22">Obesity</searchLink><br /><searchLink fieldCode="DE" term="%22Randomized+controlled+trials%22">Randomized controlled trials</searchLink><br /><searchLink fieldCode="DE" term="%22Glucose+tolerance+tests%22">Glucose tolerance tests</searchLink><br /><searchLink fieldCode="DE" term="%22Fat+content+of+milk%22">Fat content of milk</searchLink> – Name: Abstract Label: Abstract Group: Ab Data: Background: Elevated android body fat increases the risk of developing cardiometabolic diseases. Postprandial hyperglycemia contributes to the proatherogenic metabolic state evident in android adiposity. Due to the insulinotropic effect of milk‐derived proteins, postprandial hyperglycemia has been shown to be reduced with the addition of dairy products. The purpose of this study was to determine whether one serving of nonfat milk added to an oral glucose tolerance test (OGTT) could attenuate postprandial hyperglycemia in individuals with elevated android adiposity and whether these improvements would be associated with metabolic and/or peripheral hemodynamic effects. Methods: In this placebo‐controlled, randomized, crossover experimental study, 29 overweight/obese adults (26 ± 1 year) consumed an OGTT beverage (75 g glucose) combined with either nonfat milk (227 g) or a placebo control (12 g lactose + 8 g protein + 207 g water) that was matched for both carbohydrate and protein quantities. Results: In the whole sample, blood glucose and insulin concentrations increased over time in both trials with no significant differences between trials. Relative increases in peak blood glucose response were significantly related to android body fat (p < 0.05). The subjects in the highest tertiles of android body fat displayed attenuated hyperglycemic responses as well as improvements in flow‐mediated dilation (FMD) after milk intake. Conclusions: A single serving of nonfat milk may attenuate acute hyperglycemia in individuals with elevated android body fat offering a simple and convenient option for managing elevations in blood glucose. Due to the insulinotropic effect of milk‐derived proteins, postprandial hyperglycemia has been shown to be reduced with the addition of dairy products. The purpose of this study was to determine whether one serving of nonfat milk added to an oral glucose tolerance test (OGTT) could attenuate postprandial hyperglycemia in individuals with elevated android adiposity and whether these improvements would be associated with metabolic and/or peripheral hemodynamic effects. The subjects in the highest tertiles of android body fat displayed attenuated hyperglycemic responses as well as improvements in FMD after milk intake. [ABSTRACT FROM AUTHOR] – Name: AbstractSuppliedCopyright Label: Group: Ab Data: <i>Copyright of Food Science & Nutrition is the property of Wiley-Blackwell and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.) |
| PLink | https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=8gh&AN=133261056 |
| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1002/fsn3.767 Languages: – Code: eng Text: English PhysicalDescription: Pagination: PageCount: 9 StartPage: 2104 Subjects: – SubjectFull: Hyperglycemia Type: general – SubjectFull: Obesity Type: general – SubjectFull: Randomized controlled trials Type: general – SubjectFull: Glucose tolerance tests Type: general – SubjectFull: Fat content of milk Type: general Titles: – TitleFull: Nonfat milk attenuates acute hyperglycemia in individuals with android obesity: A randomized control trial. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Leary, Miriam P. – PersonEntity: Name: NameFull: Roy, Stephen J. – PersonEntity: Name: NameFull: Lim, Jisok – PersonEntity: Name: NameFull: Park, Wonil – PersonEntity: Name: NameFull: Ferrari, Rodrigo – PersonEntity: Name: NameFull: Eaves, Jared – PersonEntity: Name: NameFull: Machin, Daniel R. – PersonEntity: Name: NameFull: Tanaka, Hirofumi IsPartOfRelationships: – BibEntity: Dates: – D: 01 M: 11 Text: Nov2018 Type: published Y: 2018 Identifiers: – Type: issn-print Value: 20487177 Numbering: – Type: volume Value: 6 – Type: issue Value: 8 Titles: – TitleFull: Food Science & Nutrition Type: main |
| ResultId | 1 |
