View in EDS HTML Full Text PDF Full Text

Safety and efficacy of BioWorma® (Duddingtonia flagrans NCIMB 30336) as a feed additive for all grazing animals.

Saved in:
Bibliographic Details
Title: Safety and efficacy of BioWorma® (Duddingtonia flagrans NCIMB 30336) as a feed additive for all grazing animals.
Authors: Bampidis, Vasileios (AUTHOR), Azimonti, Giovanna (AUTHOR), Lourdes Bastos, Maria (AUTHOR), Christensen, Henrik (AUTHOR), Dusemund, Birgit (AUTHOR), Kos Durjava, Mojca (AUTHOR), Kouba, Maryline (AUTHOR), López‐Alonso, Marta (AUTHOR), López Puente, Secundino (AUTHOR), Marcon, Francesca (AUTHOR), Mayo, Baltasar (AUTHOR), Pechová, Alena (AUTHOR), Petkova, Mariana (AUTHOR), Ramos, Fernando (AUTHOR), Sanz, Yolanda (AUTHOR), Villa, Roberto Edoardo (AUTHOR), Woutersen, Ruud (AUTHOR), Chesson, Andrew (AUTHOR), Cocconcelli, Pier Sandro (AUTHOR), Rychen, Guido (AUTHOR)
Source: EFSA Journal. Jul2020, Vol. 18 Issue 7, p1-16. 16p.
Subject Terms: *Soil biology, Feed additives, Nematode-destroying fungi, Animal products, Metabolites
Company/Entity: European Commission , European Food Safety Authority
Abstract: Following a request from the European Commission, the EFSA Panel on Additives and products or Substances used in Animal Feed (FEEDAP) was asked to deliver a scientific opinion on the safety and efficacy of BioWorma® (Duddingtonia flagrans NCIMB 30336) when used as a zootechnical feed additive for all grazing animals. Duddingtonia flagrans belongs to a group of nematophagous fungi that physically entrap nematodes through an adhesive hyphal net. The additive contains the fungus in the form of chlamydospores and is intended to control pathogenic nematodes on pasture, with subsequent benefits for grazing animals. No conclusions could be drawn on the safety for the target species due to lack of data. ■■■■■ As it is not possible to exclude the presence of secondary metabolites (other than flagranones) produced during fermentation and their potential carry‐over into animal products, safety for the consumer could not be established. The Panel concluded that the additive is not irritant to skin and eyes but is irritant to the respiratory tract and a respiratory sensitiser. No conclusion could be drawn on its skin sensitisation potential. Since D. flagrans is a naturally inhabiting soil organism of world‐wide distribution, the Panel considered that use of an additive based on this organism does not pose a risk for the environment under the intended conditions of use. The strain under application reduced the number of parasitic nematodes on pasture to the benefit of grazing animals when used at the recommended application rate of 3 × 104 chlamydospores/kg bodyweight and day. [ABSTRACT FROM AUTHOR]
Copyright of EFSA Journal is the property of European Food Safety Authority and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
Database: GreenFILE
Full text is not displayed to guests.
FullText Links:
  – Type: pdflink
Text:
  Availability: 1
Header DbId: 8gh
DbLabel: GreenFILE
An: 144883702
AccessLevel: 6
PubType: Academic Journal
PubTypeId: academicJournal
PreciseRelevancyScore: 0
IllustrationInfo
Items – Name: Title
  Label: Title
  Group: Ti
  Data: Safety and efficacy of BioWorma<superscript>®</superscript> (Duddingtonia flagrans NCIMB 30336) as a feed additive for all grazing animals.
– Name: Author
  Label: Authors
  Group: Au
  Data: <searchLink fieldCode="AR" term="%22Bampidis%2C+Vasileios%22">Bampidis, Vasileios</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Azimonti%2C+Giovanna%22">Azimonti, Giovanna</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Lourdes+Bastos%2C+Maria%22">Lourdes Bastos, Maria</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Christensen%2C+Henrik%22">Christensen, Henrik</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Dusemund%2C+Birgit%22">Dusemund, Birgit</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Kos+Durjava%2C+Mojca%22">Kos Durjava, Mojca</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Kouba%2C+Maryline%22">Kouba, Maryline</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22López‐Alonso%2C+Marta%22">López‐Alonso, Marta</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22López+Puente%2C+Secundino%22">López Puente, Secundino</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Marcon%2C+Francesca%22">Marcon, Francesca</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Mayo%2C+Baltasar%22">Mayo, Baltasar</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Pechová%2C+Alena%22">Pechová, Alena</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Petkova%2C+Mariana%22">Petkova, Mariana</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Ramos%2C+Fernando%22">Ramos, Fernando</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Sanz%2C+Yolanda%22">Sanz, Yolanda</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Villa%2C+Roberto+Edoardo%22">Villa, Roberto Edoardo</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Woutersen%2C+Ruud%22">Woutersen, Ruud</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Chesson%2C+Andrew%22">Chesson, Andrew</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Cocconcelli%2C+Pier+Sandro%22">Cocconcelli, Pier Sandro</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Rychen%2C+Guido%22">Rychen, Guido</searchLink> (AUTHOR)
– Name: TitleSource
  Label: Source
  Group: Src
  Data: <searchLink fieldCode="JN" term="%22EFSA+Journal%22">EFSA Journal</searchLink>. Jul2020, Vol. 18 Issue 7, p1-16. 16p.
– Name: Subject
  Label: Subject Terms
  Group: Su
  Data: *<searchLink fieldCode="DE" term="%22Soil+biology%22">Soil biology</searchLink><br /><searchLink fieldCode="DE" term="%22Feed+additives%22">Feed additives</searchLink><br /><searchLink fieldCode="DE" term="%22Nematode-destroying+fungi%22">Nematode-destroying fungi</searchLink><br /><searchLink fieldCode="DE" term="%22Animal+products%22">Animal products</searchLink><br /><searchLink fieldCode="DE" term="%22Metabolites%22">Metabolites</searchLink>
– Name: SubjectCompany
  Label: Company/Entity
  Group: Su
  Data: <searchLink fieldCode="DE" term="%22European+Commission%22">European Commission</searchLink> <br /><searchLink fieldCode="DE" term="%22European+Food+Safety+Authority%22">European Food Safety Authority</searchLink>
– Name: Abstract
  Label: Abstract
  Group: Ab
  Data: Following a request from the European Commission, the EFSA Panel on Additives and products or Substances used in Animal Feed (FEEDAP) was asked to deliver a scientific opinion on the safety and efficacy of BioWorma® (Duddingtonia flagrans NCIMB 30336) when used as a zootechnical feed additive for all grazing animals. Duddingtonia flagrans belongs to a group of nematophagous fungi that physically entrap nematodes through an adhesive hyphal net. The additive contains the fungus in the form of chlamydospores and is intended to control pathogenic nematodes on pasture, with subsequent benefits for grazing animals. No conclusions could be drawn on the safety for the target species due to lack of data. ■■■■■ As it is not possible to exclude the presence of secondary metabolites (other than flagranones) produced during fermentation and their potential carry‐over into animal products, safety for the consumer could not be established. The Panel concluded that the additive is not irritant to skin and eyes but is irritant to the respiratory tract and a respiratory sensitiser. No conclusion could be drawn on its skin sensitisation potential. Since D. flagrans is a naturally inhabiting soil organism of world‐wide distribution, the Panel considered that use of an additive based on this organism does not pose a risk for the environment under the intended conditions of use. The strain under application reduced the number of parasitic nematodes on pasture to the benefit of grazing animals when used at the recommended application rate of 3 × 104 chlamydospores/kg bodyweight and day. [ABSTRACT FROM AUTHOR]
– Name: AbstractSuppliedCopyright
  Label:
  Group: Ab
  Data: <i>Copyright of EFSA Journal is the property of European Food Safety Authority and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.)
PLink https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=8gh&AN=144883702
RecordInfo BibRecord:
  BibEntity:
    Identifiers:
      – Type: doi
        Value: 10.2903/j.efsa.2020.6208
    Languages:
      – Code: eng
        Text: English
    PhysicalDescription:
      Pagination:
        PageCount: 16
        StartPage: 1
    Subjects:
      – SubjectFull: Soil biology
        Type: general
      – SubjectFull: Feed additives
        Type: general
      – SubjectFull: Nematode-destroying fungi
        Type: general
      – SubjectFull: Animal products
        Type: general
      – SubjectFull: Metabolites
        Type: general
      – SubjectFull: European Commission
        Type: general
      – SubjectFull: European Food Safety Authority
        Type: general
    Titles:
      – TitleFull: Safety and efficacy of BioWorma® (Duddingtonia flagrans NCIMB 30336) as a feed additive for all grazing animals.
        Type: main
  BibRelationships:
    HasContributorRelationships:
      – PersonEntity:
          Name:
            NameFull: Bampidis, Vasileios
      – PersonEntity:
          Name:
            NameFull: Azimonti, Giovanna
      – PersonEntity:
          Name:
            NameFull: Lourdes Bastos, Maria
      – PersonEntity:
          Name:
            NameFull: Christensen, Henrik
      – PersonEntity:
          Name:
            NameFull: Dusemund, Birgit
      – PersonEntity:
          Name:
            NameFull: Kos Durjava, Mojca
      – PersonEntity:
          Name:
            NameFull: Kouba, Maryline
      – PersonEntity:
          Name:
            NameFull: López‐Alonso, Marta
      – PersonEntity:
          Name:
            NameFull: López Puente, Secundino
      – PersonEntity:
          Name:
            NameFull: Marcon, Francesca
      – PersonEntity:
          Name:
            NameFull: Mayo, Baltasar
      – PersonEntity:
          Name:
            NameFull: Pechová, Alena
      – PersonEntity:
          Name:
            NameFull: Petkova, Mariana
      – PersonEntity:
          Name:
            NameFull: Ramos, Fernando
      – PersonEntity:
          Name:
            NameFull: Sanz, Yolanda
      – PersonEntity:
          Name:
            NameFull: Villa, Roberto Edoardo
      – PersonEntity:
          Name:
            NameFull: Woutersen, Ruud
      – PersonEntity:
          Name:
            NameFull: Chesson, Andrew
      – PersonEntity:
          Name:
            NameFull: Cocconcelli, Pier Sandro
      – PersonEntity:
          Name:
            NameFull: Rychen, Guido
    IsPartOfRelationships:
      – BibEntity:
          Dates:
            – D: 01
              M: 07
              Text: Jul2020
              Type: published
              Y: 2020
          Identifiers:
            – Type: issn-print
              Value: 18314732
          Numbering:
            – Type: volume
              Value: 18
            – Type: issue
              Value: 7
          Titles:
            – TitleFull: EFSA Journal
              Type: main
ResultId 1