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Efficacy of the feed additive consisting of Bacillus velezensisNRRL B‐67259 (Correlink™ ABS1781) as a feed additive for all growing poultry species (Elanco GmbH)

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Title: Efficacy of the feed additive consisting of Bacillus velezensisNRRL B‐67259 (Correlink™ ABS1781) as a feed additive for all growing poultry species (Elanco GmbH)
Authors: Bampidis, Vasileios (AUTHOR), Azimonti, Giovanna (AUTHOR), Bastos, Maria de Lourdes (AUTHOR), Christensen, Henrik (AUTHOR), Dusemund, Birgit (AUTHOR), Fašmon Durjava, Mojca (AUTHOR), Kouba, Maryline (AUTHOR), López‐Alonso, Marta (AUTHOR), López Puente, Secundino (AUTHOR), Marcon, Francesca (AUTHOR), Mayo, Baltasar (AUTHOR), Pechová, Alena (AUTHOR), Petkova, Mariana (AUTHOR), Ramos, Fernando (AUTHOR), Sanz, Yolanda (AUTHOR), Villa, Roberto Edoardo (AUTHOR), Woutersen, Ruud (AUTHOR), Prieto, Miguel (AUTHOR), Anguita, Montserrat (AUTHOR), Pettenati, Elisa (AUTHOR)
Source: EFSA Journal. Dec2022, Vol. 20 Issue 12, p1-7. 7p.
Abstract: Following a request from the European Commission, EFSA was asked to deliver a scientific opinion on the efficacy of a product consisting of spores of Bacillus velezensis NRRL B‐67257 as a zootechnical additive for chickens for fattening, chickens reared for laying, turkeys for fattening, turkeys reared for breeding and minor poultry species. The additive has the tradename Correlink™ ABS1781 Bacillus subtilis and is not currently authorised in the EU. It is intended for use in complete feed for the target species at a minimum inclusion level of 1.5 × 108 CFU/kg complete feed. In a previous opinion, the FEEDAP Panel could not conclude on the efficacy of the additive for the poultry species due to the potential cross‐contamination of the control diets in two of the three studies provided. The applicant has provided supplementary information to exclude this possibility. The new data showed that the gene used as marker in the previous analyses is non‐specific of the NRRL B‐67259 strain, which precluded the adequate quantification of the active agent in the feeds used in the studies. Moreover, in a second analysis, the active agent could not be isolated from the field excreta samples collected from either the treated or the control group in the two formerly submitted efficacy studies. The Panel concluded that the methodology was not able to discriminate between the strain under assessment and the background. Additionally, two new efficacy trials with chickens for fattening were provided to support the efficacy of the additive. However, none could be further considered since the husbandry conditions in which the birds were kept were non‐compliant with Directive 2007/43/EC. Therefore, the FEEDAP Panel was not in the position to conclude on the efficacy of Correlink™ ABS1781 for all growing poultry species. [ABSTRACT FROM AUTHOR]
Copyright of EFSA Journal is the property of European Food Safety Authority and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
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  Data: Efficacy of the feed additive consisting of Bacillus velezensisNRRL B‐67259 (Correlink™ ABS1781) as a feed additive for all growing poultry species (Elanco GmbH)
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  Data: <searchLink fieldCode="AR" term="%22Bampidis%2C+Vasileios%22">Bampidis, Vasileios</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Azimonti%2C+Giovanna%22">Azimonti, Giovanna</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Bastos%2C+Maria+de+Lourdes%22">Bastos, Maria de Lourdes</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Christensen%2C+Henrik%22">Christensen, Henrik</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Dusemund%2C+Birgit%22">Dusemund, Birgit</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Fašmon+Durjava%2C+Mojca%22">Fašmon Durjava, Mojca</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Kouba%2C+Maryline%22">Kouba, Maryline</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22López‐Alonso%2C+Marta%22">López‐Alonso, Marta</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22López+Puente%2C+Secundino%22">López Puente, Secundino</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Marcon%2C+Francesca%22">Marcon, Francesca</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Mayo%2C+Baltasar%22">Mayo, Baltasar</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Pechová%2C+Alena%22">Pechová, Alena</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Petkova%2C+Mariana%22">Petkova, Mariana</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Ramos%2C+Fernando%22">Ramos, Fernando</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Sanz%2C+Yolanda%22">Sanz, Yolanda</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Villa%2C+Roberto+Edoardo%22">Villa, Roberto Edoardo</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Woutersen%2C+Ruud%22">Woutersen, Ruud</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Prieto%2C+Miguel%22">Prieto, Miguel</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Anguita%2C+Montserrat%22">Anguita, Montserrat</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Pettenati%2C+Elisa%22">Pettenati, Elisa</searchLink> (AUTHOR)
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  Data: <searchLink fieldCode="JN" term="%22EFSA+Journal%22">EFSA Journal</searchLink>. Dec2022, Vol. 20 Issue 12, p1-7. 7p.
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  Data: Following a request from the European Commission, EFSA was asked to deliver a scientific opinion on the efficacy of a product consisting of spores of Bacillus velezensis NRRL B‐67257 as a zootechnical additive for chickens for fattening, chickens reared for laying, turkeys for fattening, turkeys reared for breeding and minor poultry species. The additive has the tradename Correlink™ ABS1781 Bacillus subtilis and is not currently authorised in the EU. It is intended for use in complete feed for the target species at a minimum inclusion level of 1.5 × 108 CFU/kg complete feed. In a previous opinion, the FEEDAP Panel could not conclude on the efficacy of the additive for the poultry species due to the potential cross‐contamination of the control diets in two of the three studies provided. The applicant has provided supplementary information to exclude this possibility. The new data showed that the gene used as marker in the previous analyses is non‐specific of the NRRL B‐67259 strain, which precluded the adequate quantification of the active agent in the feeds used in the studies. Moreover, in a second analysis, the active agent could not be isolated from the field excreta samples collected from either the treated or the control group in the two formerly submitted efficacy studies. The Panel concluded that the methodology was not able to discriminate between the strain under assessment and the background. Additionally, two new efficacy trials with chickens for fattening were provided to support the efficacy of the additive. However, none could be further considered since the husbandry conditions in which the birds were kept were non‐compliant with Directive 2007/43/EC. Therefore, the FEEDAP Panel was not in the position to conclude on the efficacy of Correlink™ ABS1781 for all growing poultry species. [ABSTRACT FROM AUTHOR]
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  Data: <i>Copyright of EFSA Journal is the property of European Food Safety Authority and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.)
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