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Combined health effects of air pollutant mixtures on respiratory mortality using BKMR in Hangzhou, China.

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Title: Combined health effects of air pollutant mixtures on respiratory mortality using BKMR in Hangzhou, China.
Authors: Zhou, Xiaocong1 (AUTHOR), Fang, Zisi1 (AUTHOR), Lv, Ye2 (AUTHOR), Li, Chaokang2 (AUTHOR), Xu, Shanshan2 (AUTHOR), Cheng, Keyi2 (AUTHOR), Ren, Yanjun2 (AUTHOR), Lv, Na2 (AUTHOR), Gao, Bing2 (AUTHOR), Xu, Hong2 (AUTHOR) xuhong-123456@hotmail.com
Source: Journal of the Air & Waste Management Association (Taylor & Francis Ltd). Dec2024, Vol. 74 Issue 12, p884-894. 11p.
Subject Terms: *Air pollutants, *Air pollution, *Pollutants, Respiratory organs, Regression analysis
Abstract: Previous research on respiratory system mortality primarily focused on understanding their combined effects and have neglected the fact that air pollution mixtures are interrelated. This study used Bayesian kernel machine regression (BKMR) to analyze the relationship between air pollutant mixtures and respiratory mortality in Hangzhou, China from 2014 to 2018. The results showed a significant association between pollutant mixtures and respiratory system mortality primarily driven by PM2.5 and SO2. The joint exposure of air pollutants was positively correlated with respiratory system mortality at lag 01 and lag 02 days. The estimated joint effects of log-transformed mixture air pollution exposure on log-transformed respiratory system mortality increased from −0.02 (95% CI: −0.08–0.02) and −0.01 (95% CI: −0.05–0.04) at the 25th percentile to 0.06 (95% CI: 0.01–0.12) and 0.04 (95% CI: −0.001, 0.09) at the 75th percentile. Additionally, there was evidence of an interaction between O3 and PM10. This study confirms that exposure to multiple pollutants is a significant public health problem facing the Hangzhou population given the compounded effect proven with regression analysis, while furthermore, the control of PM2.5 and SO2 also represents a serious concern. Implications: Evidence indicates interactions between O3 and PM10. This study demonstrates that exposure to multiple pollutants exerts combined effects on the public health of the Hangzhou population, highlighting the importance of controlling PM2.5 and SO2. [ABSTRACT FROM AUTHOR]
Copyright of Journal of the Air & Waste Management Association (Taylor & Francis Ltd) is the property of Taylor & Francis Ltd and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
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  Data: Combined health effects of air pollutant mixtures on respiratory mortality using BKMR in Hangzhou, China.
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  Data: <searchLink fieldCode="AR" term="%22Zhou%2C+Xiaocong%22">Zhou, Xiaocong</searchLink><relatesTo>1</relatesTo> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Fang%2C+Zisi%22">Fang, Zisi</searchLink><relatesTo>1</relatesTo> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Lv%2C+Ye%22">Lv, Ye</searchLink><relatesTo>2</relatesTo> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Li%2C+Chaokang%22">Li, Chaokang</searchLink><relatesTo>2</relatesTo> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Xu%2C+Shanshan%22">Xu, Shanshan</searchLink><relatesTo>2</relatesTo> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Cheng%2C+Keyi%22">Cheng, Keyi</searchLink><relatesTo>2</relatesTo> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Ren%2C+Yanjun%22">Ren, Yanjun</searchLink><relatesTo>2</relatesTo> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Lv%2C+Na%22">Lv, Na</searchLink><relatesTo>2</relatesTo> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Gao%2C+Bing%22">Gao, Bing</searchLink><relatesTo>2</relatesTo> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Xu%2C+Hong%22">Xu, Hong</searchLink><relatesTo>2</relatesTo> (AUTHOR)<i> xuhong-123456@hotmail.com</i>
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  Data: *<searchLink fieldCode="DE" term="%22Air+pollutants%22">Air pollutants</searchLink><br />*<searchLink fieldCode="DE" term="%22Air+pollution%22">Air pollution</searchLink><br />*<searchLink fieldCode="DE" term="%22Pollutants%22">Pollutants</searchLink><br /><searchLink fieldCode="DE" term="%22Respiratory+organs%22">Respiratory organs</searchLink><br /><searchLink fieldCode="DE" term="%22Regression+analysis%22">Regression analysis</searchLink>
– Name: Abstract
  Label: Abstract
  Group: Ab
  Data: Previous research on respiratory system mortality primarily focused on understanding their combined effects and have neglected the fact that air pollution mixtures are interrelated. This study used Bayesian kernel machine regression (BKMR) to analyze the relationship between air pollutant mixtures and respiratory mortality in Hangzhou, China from 2014 to 2018. The results showed a significant association between pollutant mixtures and respiratory system mortality primarily driven by PM2.5 and SO2. The joint exposure of air pollutants was positively correlated with respiratory system mortality at lag 01 and lag 02 days. The estimated joint effects of log-transformed mixture air pollution exposure on log-transformed respiratory system mortality increased from −0.02 (95% CI: −0.08–0.02) and −0.01 (95% CI: −0.05–0.04) at the 25th percentile to 0.06 (95% CI: 0.01–0.12) and 0.04 (95% CI: −0.001, 0.09) at the 75th percentile. Additionally, there was evidence of an interaction between O3 and PM10. This study confirms that exposure to multiple pollutants is a significant public health problem facing the Hangzhou population given the compounded effect proven with regression analysis, while furthermore, the control of PM2.5 and SO2 also represents a serious concern. Implications: Evidence indicates interactions between O3 and PM10. This study demonstrates that exposure to multiple pollutants exerts combined effects on the public health of the Hangzhou population, highlighting the importance of controlling PM2.5 and SO2. [ABSTRACT FROM AUTHOR]
– Name: AbstractSuppliedCopyright
  Label:
  Group: Ab
  Data: <i>Copyright of Journal of the Air & Waste Management Association (Taylor & Francis Ltd) is the property of Taylor & Francis Ltd and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.)
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RecordInfo BibRecord:
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      – Type: doi
        Value: 10.1080/10962247.2024.2411033
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      – Code: eng
        Text: English
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        PageCount: 11
        StartPage: 884
    Subjects:
      – SubjectFull: Air pollutants
        Type: general
      – SubjectFull: Air pollution
        Type: general
      – SubjectFull: Pollutants
        Type: general
      – SubjectFull: Respiratory organs
        Type: general
      – SubjectFull: Regression analysis
        Type: general
    Titles:
      – TitleFull: Combined health effects of air pollutant mixtures on respiratory mortality using BKMR in Hangzhou, China.
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            NameFull: Zhou, Xiaocong
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            NameFull: Fang, Zisi
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              M: 12
              Text: Dec2024
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              Y: 2024
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