Updated peer review of the pesticide risk assessment of the active substance clodinafop (variant evaluated clodinafop‐propargyl).

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Title: Updated peer review of the pesticide risk assessment of the active substance clodinafop (variant evaluated clodinafop‐propargyl).
Authors: Álvarez, Fernando (AUTHOR), Arena, Maria (AUTHOR), Auteri, Domenica (AUTHOR), Leite, Sofia Batista (AUTHOR), Binaglia, Marco (AUTHOR), Castoldi, Anna Federica (AUTHOR), Chiusolo, Arianna (AUTHOR), Colagiorgi, Angelo (AUTHOR), Colas, Mathilde (AUTHOR), Crivellente, Federica (AUTHOR), De Lentdecker, Chloe (AUTHOR), De Magistris, Isabella (AUTHOR), Egsmose, Mark (AUTHOR), Fait, Gabriella (AUTHOR), Ferilli, Franco (AUTHOR), Santonja, German Giner (AUTHOR), Gouliarmou, Varvara (AUTHOR), Halling, Katrin (AUTHOR), Ippolito, Alessio (AUTHOR), Istace, Frederique (AUTHOR)
Source: EFSA Journal. Mar2026, Vol. 24 Issue 3, p1-23. 23p.
Subject Terms: *Herbicides, *Endocrine disruptors, *Pesticide pollution, Occupational exposure, Scholarly peer review
Company/Entity: European Food Safety Authority , European Union , European Commission
Abstract: The conclusions of the European Food Safety Authority (EFSA) following the peer review of the initial risk assessments carried out by the competent authorities of the rapporteur Member State, Greece, and co‐rapporteur Member State, Germany, for the pesticide active substance clodinafop‐propargyl are reported. The context of the peer review was that required by Commission Implementing Regulation (EU) No 844/2012. The conclusions were reached on the basis of the evaluation of the representative uses of clodinafop‐propargyl as a herbicide on wheat, rye and triticale. The reliable end points, appropriate for use in regulatory risk assessment, are presented. Missing information identified as being required by the regulatory framework is listed. Concerns are identified. The European Commission mandated EFSA to reconsider the acceptable operator exposure level (AOEL) setting and to update the non‐dietary exposure assessment if needed. In addition, the conclusions were updated with regard to the endocrine‐disrupting properties following a mandate received from the European Commission in November 2020. [ABSTRACT FROM AUTHOR]
Copyright of EFSA Journal is the property of European Food Safety Authority and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
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  Data: Updated peer review of the pesticide risk assessment of the active substance clodinafop (variant evaluated clodinafop‐propargyl).
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  Data: <searchLink fieldCode="AR" term="%22Álvarez%2C+Fernando%22">Álvarez, Fernando</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Arena%2C+Maria%22">Arena, Maria</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Auteri%2C+Domenica%22">Auteri, Domenica</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Leite%2C+Sofia+Batista%22">Leite, Sofia Batista</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Binaglia%2C+Marco%22">Binaglia, Marco</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Castoldi%2C+Anna+Federica%22">Castoldi, Anna Federica</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Chiusolo%2C+Arianna%22">Chiusolo, Arianna</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Colagiorgi%2C+Angelo%22">Colagiorgi, Angelo</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Colas%2C+Mathilde%22">Colas, Mathilde</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Crivellente%2C+Federica%22">Crivellente, Federica</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22De+Lentdecker%2C+Chloe%22">De Lentdecker, Chloe</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22De+Magistris%2C+Isabella%22">De Magistris, Isabella</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Egsmose%2C+Mark%22">Egsmose, Mark</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Fait%2C+Gabriella%22">Fait, Gabriella</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Ferilli%2C+Franco%22">Ferilli, Franco</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Santonja%2C+German+Giner%22">Santonja, German Giner</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Gouliarmou%2C+Varvara%22">Gouliarmou, Varvara</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Halling%2C+Katrin%22">Halling, Katrin</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Ippolito%2C+Alessio%22">Ippolito, Alessio</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Istace%2C+Frederique%22">Istace, Frederique</searchLink> (AUTHOR)
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  Data: <searchLink fieldCode="JN" term="%22EFSA+Journal%22">EFSA Journal</searchLink>. Mar2026, Vol. 24 Issue 3, p1-23. 23p.
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  Data: *<searchLink fieldCode="DE" term="%22Herbicides%22">Herbicides</searchLink><br />*<searchLink fieldCode="DE" term="%22Endocrine+disruptors%22">Endocrine disruptors</searchLink><br />*<searchLink fieldCode="DE" term="%22Pesticide+pollution%22">Pesticide pollution</searchLink><br /><searchLink fieldCode="DE" term="%22Occupational+exposure%22">Occupational exposure</searchLink><br /><searchLink fieldCode="DE" term="%22Scholarly+peer+review%22">Scholarly peer review</searchLink>
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  Data: <searchLink fieldCode="DE" term="%22European+Food+Safety+Authority%22">European Food Safety Authority</searchLink> <br /><searchLink fieldCode="DE" term="%22European+Union%22">European Union</searchLink> <br /><searchLink fieldCode="DE" term="%22European+Commission%22">European Commission</searchLink>
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  Label: Abstract
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  Data: The conclusions of the European Food Safety Authority (EFSA) following the peer review of the initial risk assessments carried out by the competent authorities of the rapporteur Member State, Greece, and co‐rapporteur Member State, Germany, for the pesticide active substance clodinafop‐propargyl are reported. The context of the peer review was that required by Commission Implementing Regulation (EU) No 844/2012. The conclusions were reached on the basis of the evaluation of the representative uses of clodinafop‐propargyl as a herbicide on wheat, rye and triticale. The reliable end points, appropriate for use in regulatory risk assessment, are presented. Missing information identified as being required by the regulatory framework is listed. Concerns are identified. The European Commission mandated EFSA to reconsider the acceptable operator exposure level (AOEL) setting and to update the non‐dietary exposure assessment if needed. In addition, the conclusions were updated with regard to the endocrine‐disrupting properties following a mandate received from the European Commission in November 2020. [ABSTRACT FROM AUTHOR]
– Name: AbstractSuppliedCopyright
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  Data: <i>Copyright of EFSA Journal is the property of European Food Safety Authority and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.)
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      – Type: doi
        Value: 10.2903/j.efsa.2026.9871
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      – Code: eng
        Text: English
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      – SubjectFull: Herbicides
        Type: general
      – SubjectFull: Endocrine disruptors
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      – SubjectFull: Pesticide pollution
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              Text: Mar2026
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