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Scalable Synthesis of Highly Pure (R)‐3‐Fluoropyrrolidine From (S)‐4‐Chloro‐3‐hydroxybutyronitrile.

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Title: Scalable Synthesis of Highly Pure (R)‐3‐Fluoropyrrolidine From (S)‐4‐Chloro‐3‐hydroxybutyronitrile.
Authors: Bold, Christian P.1, christian.bold@dottikon.com, Engl, Pascal S.2, pascal.engl@roche.com, Stutz, Alfred1, Stöckli, Markus1, Krämer, Matthias1, Fantasia, Serena M.2, Metzger, Albrecht2, Moessner, Christian2, Tosatti, Paolo2, Hildbrand, Stefan2
Source: Helvetica Chimica Acta; Jan2026, Vol. 109 Issue 1, p1-16, 16p
Database: Applied Science & Technology Source
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Header DbId: aci
DbLabel: Applied Science & Technology Source
An: 190936318
AccessLevel: 2
PubType: Academic Journal
PubTypeId: academicJournal
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  Data: <searchLink fieldCode="AU" term="%22Bold%2C+Christian+P%2E%22">Bold, Christian P.</searchLink><relatesTo>1</relatesTo>, <i>christian.bold@dottikon.com</i><br /><searchLink fieldCode="AU" term="%22Engl%2C+Pascal+S%2E%22">Engl, Pascal S.</searchLink><relatesTo>2</relatesTo>, <i>pascal.engl@roche.com</i><br /><searchLink fieldCode="AU" term="%22Stutz%2C+Alfred%22">Stutz, Alfred</searchLink><relatesTo>1</relatesTo><br /><searchLink fieldCode="AU" term="%22Stöckli%2C+Markus%22">Stöckli, Markus</searchLink><relatesTo>1</relatesTo><br /><searchLink fieldCode="AU" term="%22Krämer%2C+Matthias%22">Krämer, Matthias</searchLink><relatesTo>1</relatesTo><br /><searchLink fieldCode="AU" term="%22Fantasia%2C+Serena+M%2E%22">Fantasia, Serena M.</searchLink><relatesTo>2</relatesTo><br /><searchLink fieldCode="AU" term="%22Metzger%2C+Albrecht%22">Metzger, Albrecht</searchLink><relatesTo>2</relatesTo><br /><searchLink fieldCode="AU" term="%22Moessner%2C+Christian%22">Moessner, Christian</searchLink><relatesTo>2</relatesTo><br /><searchLink fieldCode="AU" term="%22Tosatti%2C+Paolo%22">Tosatti, Paolo</searchLink><relatesTo>2</relatesTo><br /><searchLink fieldCode="AU" term="%22Hildbrand%2C+Stefan%22">Hildbrand, Stefan</searchLink><relatesTo>2</relatesTo>
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  Data: <searchLink fieldCode="JN" term="%22Helvetica+Chimica+Acta%22">Helvetica Chimica Acta</searchLink>; Jan2026, Vol. 109 Issue 1, p1-16, 16p
PLink https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=aci&AN=190936318
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        Value: 10.1002/hlca.202500164
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              Text: Jan2026
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