Targeting WEE1 in ARID1A/TP53 Concurrent Mutant Colorectal Cancer by Exploiting R‐Loop Accumulation and DNA Repair Deficiencies.
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| Title: | Targeting WEE1 in ARID1A/TP53 Concurrent Mutant Colorectal Cancer by Exploiting R‐Loop Accumulation and DNA Repair Deficiencies. |
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| Authors: | Zhang, Chi1,2, Zhu, Yanjing1,2, Ai, Luoyan1,2, Wang, Jingyuan1,2, Yu, Shan1,2, Wang, Yichen3, Xu, Xiaojing1,2, Liu, Mengling1,2, Yu, Yiyi1,2, Zhu, Mengxuan1,2, Liu, Yutong1,2, Xu, Zhenghang1,2, Zhou, Haojie1,2, Li, Huishan1,2, Huang, Qihong2, Liu, Qing1,2, liu.qing@zs-hospital.sh.cn, Peng, Ke1,2, peng.ke@zs-hospital.sh.cn, Liu, Tianshu1,2,4,5,6, liu.tianshu@zs-hospital.sh.cn |
| Source: | Advanced Science; 2/13/2026, Vol. 13 Issue 9, p1-17, 17p |
| Database: | Applied Science & Technology Source |
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| Header | DbId: aci DbLabel: Applied Science & Technology Source An: 191576861 AccessLevel: 2 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: Targeting WEE1 in ARID1A/TP53 Concurrent Mutant Colorectal Cancer by Exploiting R‐Loop Accumulation and DNA Repair Deficiencies. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AU" term="%22Zhang%2C+Chi%22">Zhang, Chi</searchLink><relatesTo>1,2</relatesTo><br /><searchLink fieldCode="AU" term="%22Zhu%2C+Yanjing%22">Zhu, Yanjing</searchLink><relatesTo>1,2</relatesTo><br /><searchLink fieldCode="AU" term="%22Ai%2C+Luoyan%22">Ai, Luoyan</searchLink><relatesTo>1,2</relatesTo><br /><searchLink fieldCode="AU" term="%22Wang%2C+Jingyuan%22">Wang, Jingyuan</searchLink><relatesTo>1,2</relatesTo><br /><searchLink fieldCode="AU" term="%22Yu%2C+Shan%22">Yu, Shan</searchLink><relatesTo>1,2</relatesTo><br /><searchLink fieldCode="AU" term="%22Wang%2C+Yichen%22">Wang, Yichen</searchLink><relatesTo>3</relatesTo><br /><searchLink fieldCode="AU" term="%22Xu%2C+Xiaojing%22">Xu, Xiaojing</searchLink><relatesTo>1,2</relatesTo><br /><searchLink fieldCode="AU" term="%22Liu%2C+Mengling%22">Liu, Mengling</searchLink><relatesTo>1,2</relatesTo><br /><searchLink fieldCode="AU" term="%22Yu%2C+Yiyi%22">Yu, Yiyi</searchLink><relatesTo>1,2</relatesTo><br /><searchLink fieldCode="AU" term="%22Zhu%2C+Mengxuan%22">Zhu, Mengxuan</searchLink><relatesTo>1,2</relatesTo><br /><searchLink fieldCode="AU" term="%22Liu%2C+Yutong%22">Liu, Yutong</searchLink><relatesTo>1,2</relatesTo><br /><searchLink fieldCode="AU" term="%22Xu%2C+Zhenghang%22">Xu, Zhenghang</searchLink><relatesTo>1,2</relatesTo><br /><searchLink fieldCode="AU" term="%22Zhou%2C+Haojie%22">Zhou, Haojie</searchLink><relatesTo>1,2</relatesTo><br /><searchLink fieldCode="AU" term="%22Li%2C+Huishan%22">Li, Huishan</searchLink><relatesTo>1,2</relatesTo><br /><searchLink fieldCode="AU" term="%22Huang%2C+Qihong%22">Huang, Qihong</searchLink><relatesTo>2</relatesTo><br /><searchLink fieldCode="AU" term="%22Liu%2C+Qing%22">Liu, Qing</searchLink><relatesTo>1,2</relatesTo>, <i>liu.qing@zs-hospital.sh.cn</i><br /><searchLink fieldCode="AU" term="%22Peng%2C+Ke%22">Peng, Ke</searchLink><relatesTo>1,2</relatesTo>, <i>peng.ke@zs-hospital.sh.cn</i><br /><searchLink fieldCode="AU" term="%22Liu%2C+Tianshu%22">Liu, Tianshu</searchLink><relatesTo>1,2,4,5,6</relatesTo>, <i>liu.tianshu@zs-hospital.sh.cn</i> – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%22Advanced+Science%22">Advanced Science</searchLink>; 2/13/2026, Vol. 13 Issue 9, p1-17, 17p |
| PLink | https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=aci&AN=191576861 |
| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1002/advs.202512074 Languages: – Code: eng Text: English PhysicalDescription: Pagination: PageCount: 17 StartPage: 1 Titles: – TitleFull: Targeting WEE1 in ARID1A/TP53 Concurrent Mutant Colorectal Cancer by Exploiting R‐Loop Accumulation and DNA Repair Deficiencies. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Zhang, Chi – PersonEntity: Name: NameFull: Zhu, Yanjing – PersonEntity: Name: NameFull: Ai, Luoyan – PersonEntity: Name: NameFull: Wang, Jingyuan – PersonEntity: Name: NameFull: Yu, Shan – PersonEntity: Name: NameFull: Wang, Yichen – PersonEntity: Name: NameFull: Xu, Xiaojing – PersonEntity: Name: NameFull: Liu, Mengling – PersonEntity: Name: NameFull: Yu, Yiyi – PersonEntity: Name: NameFull: Zhu, Mengxuan – PersonEntity: Name: NameFull: Liu, Yutong – PersonEntity: Name: NameFull: Xu, Zhenghang – PersonEntity: Name: NameFull: Zhou, Haojie – PersonEntity: Name: NameFull: Li, Huishan – PersonEntity: Name: NameFull: Huang, Qihong – PersonEntity: Name: NameFull: Liu, Qing – PersonEntity: Name: NameFull: Peng, Ke – PersonEntity: Name: NameFull: Liu, Tianshu IsPartOfRelationships: – BibEntity: Dates: – D: 13 M: 02 Text: 2/13/2026 Type: published Y: 2026 Identifiers: – Type: issn-print Value: 21983844 Numbering: – Type: volume Value: 13 – Type: issue Value: 9 Titles: – TitleFull: Advanced Science Type: main |
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