Chronic co-exposure to BPA and alcohol synergizes hepatotoxicity via dysregulation of glycerolipid metabolism and ceramide/HtrA2-driven apoptosis in HepG2 cells.

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Title: Chronic co-exposure to BPA and alcohol synergizes hepatotoxicity via dysregulation of glycerolipid metabolism and ceramide/HtrA2-driven apoptosis in HepG2 cells.
Authors: Tan, Yan Qin1, Shih, Chia-Lung1,2, Chen, Yi-Chia3, Lee, Sheng-Han4,5, Yang, Ji-Rui3,6, Kuo, Chan-Yen7, Chiou, Yi-Shiou1,3, chiouyishiou@kmu.edu.tw
Source: Journal of Hazardous Materials; Feb2026, Vol. 504, pN.PAG-N.PAG, 1p
Database: Applied Science & Technology Source
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  Availability: 0
Header DbId: aci
DbLabel: Applied Science & Technology Source
An: 191634159
AccessLevel: 2
PubType: Academic Journal
PubTypeId: academicJournal
PreciseRelevancyScore: 0
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  Label: Title
  Group: Ti
  Data: Chronic co-exposure to BPA and alcohol synergizes hepatotoxicity via dysregulation of glycerolipid metabolism and ceramide/HtrA2-driven apoptosis in HepG2 cells.
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  Label: Authors
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  Data: <searchLink fieldCode="AU" term="%22Tan%2C+Yan+Qin%22">Tan, Yan Qin</searchLink><relatesTo>1</relatesTo><br /><searchLink fieldCode="AU" term="%22Shih%2C+Chia-Lung%22">Shih, Chia-Lung</searchLink><relatesTo>1,2</relatesTo><br /><searchLink fieldCode="AU" term="%22Chen%2C+Yi-Chia%22">Chen, Yi-Chia</searchLink><relatesTo>3</relatesTo><br /><searchLink fieldCode="AU" term="%22Lee%2C+Sheng-Han%22">Lee, Sheng-Han</searchLink><relatesTo>4,5</relatesTo><br /><searchLink fieldCode="AU" term="%22Yang%2C+Ji-Rui%22">Yang, Ji-Rui</searchLink><relatesTo>3,6</relatesTo><br /><searchLink fieldCode="AU" term="%22Kuo%2C+Chan-Yen%22">Kuo, Chan-Yen</searchLink><relatesTo>7</relatesTo><br /><searchLink fieldCode="AU" term="%22Chiou%2C+Yi-Shiou%22">Chiou, Yi-Shiou</searchLink><relatesTo>1,3</relatesTo>, <i>chiouyishiou@kmu.edu.tw</i>
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  Data: <searchLink fieldCode="JN" term="%22Journal+of+Hazardous+Materials%22">Journal of Hazardous Materials</searchLink>; Feb2026, Vol. 504, pN.PAG-N.PAG, 1p
PLink https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=aci&AN=191634159
RecordInfo BibRecord:
  BibEntity:
    Identifiers:
      – Type: doi
        Value: 10.1016/j.jhazmat.2026.141290
    Languages:
      – Code: eng
        Text: English
    PhysicalDescription:
      Pagination:
        PageCount: 1
        StartPage: N.PAG
    Titles:
      – TitleFull: Chronic co-exposure to BPA and alcohol synergizes hepatotoxicity via dysregulation of glycerolipid metabolism and ceramide/HtrA2-driven apoptosis in HepG2 cells.
        Type: main
  BibRelationships:
    HasContributorRelationships:
      – PersonEntity:
          Name:
            NameFull: Tan, Yan Qin
      – PersonEntity:
          Name:
            NameFull: Shih, Chia-Lung
      – PersonEntity:
          Name:
            NameFull: Chen, Yi-Chia
      – PersonEntity:
          Name:
            NameFull: Lee, Sheng-Han
      – PersonEntity:
          Name:
            NameFull: Yang, Ji-Rui
      – PersonEntity:
          Name:
            NameFull: Kuo, Chan-Yen
      – PersonEntity:
          Name:
            NameFull: Chiou, Yi-Shiou
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      – BibEntity:
          Dates:
            – D: 15
              M: 02
              Text: Feb2026
              Type: published
              Y: 2026
          Identifiers:
            – Type: issn-print
              Value: 03043894
          Numbering:
            – Type: volume
              Value: 504
          Titles:
            – TitleFull: Journal of Hazardous Materials
              Type: main
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