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Lead Optimization and Modulationof hERG Activityin a Series of Aminooxazoline Xanthene β-Site AmyloidPrecursor Protein Cleaving Enzyme (BACE1) Inhibitors.

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Title: Lead Optimization and Modulationof hERG Activityin a Series of Aminooxazoline Xanthene β-Site AmyloidPrecursor Protein Cleaving Enzyme (BACE1) Inhibitors.
Authors: Epstein, Oleg1, Bryan, Marian C.1, Cheng, Alan C.1, Derakhchan, Katayoun1, Dineen, Thomas A.1, Hickman, Dean1, Hua, Zihao1, Human, Jason B.1, Kreiman, Charles1, Marx, Isaac E.1, Weiss, Matthew M.1, Wahl, Robert C.1, Wen, Paul H.1, Whittington, Douglas A.1, Wood, Stephen1, Zheng, Xiao Mei1, Fremeau, Robert T.1, White, Ryan D.1, Patel, Vinod F.1
Source: Journal of Medicinal Chemistry. Dec2014, Vol. 57 Issue 23, p9796-9810. 15p.
Database: Academic Search Ultimate
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PubType: Academic Journal
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