The helminth product, ES-62 modulates dendritic cell responses by inducing the selective autophagolysosomal degradation of TLR-transducers, as exemplified by PKCδ. - Eason, Russell J.; Bell, Kara S.; Marshall, Fraser A.; Rodgers, David T.; Pineda, Miguel A.; Steiger, Christina N.; Al-Riyami, Lamyaa; Harnett, William; Harnett, Margaret M. (Scientific Reports, 2016)