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Investigation of the mycobacterial enzyme HsaD as a potential novel target for anti-tubercular agents using a fragment-based drug design approach.

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Title: Investigation of the mycobacterial enzyme HsaD as a potential novel target for anti-tubercular agents using a fragment-based drug design approach.
Authors: Ryan, Ali1, Polycarpou, Elena1, Lack, Nathan A2,3, Evangelopoulos, Dimitrios4,5,6, Sieg, Christian1, Halman, Alice1, Bhakta, Sanjib4, Eleftheriadou, Olga1, McHugh, Timothy D5, Keany, Sebastian2, Lowe, Edward D7, Ballet, Romain2, Abuhammad, Areej8, Jacobs, William R9, Ciulli, Alessio10,11, Sim, Edith1,2 edith.sim@pharm.ox.ac.uk, Jacobs, William R Jr12 (AUTHOR)
Source: British Journal of Pharmacology. Jul2017, Vol. 174 Issue 14, p2209-2224. 16p. 2 Diagrams, 3 Charts, 2 Graphs.
Database: Academic Search Ultimate
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ISSN:00071188
DOI:10.1111/bph.13810