Nuclease activity gives an edge to host-defense peptide piscidin 3 over piscidin 1, rendering it more effective against persisters and biofilms. - Libardo, M. Daben J.; Bahar, Ali A.; Ma, Buyong; Fu, Riqiang; McCormick, Laura E.; Zhao, Jun; McCallum, Scott A.; Nussinov, Ruth; Ren, Dacheng; Angeles‐Boza, Alfredo M.; Cotten, Myriam L. (FEBS Journal, 2017)