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Discovery of novel 2,4-diarylaminopyrimidine derivatives as potent and selective epidermal growth factor receptor (EGFR) inhibitors against L858R/T790M resistance mutation.

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Title: Discovery of novel 2,4-diarylaminopyrimidine derivatives as potent and selective epidermal growth factor receptor (EGFR) inhibitors against L858R/T790M resistance mutation.
Authors: Yan, Qi1, Chen, Yuzhe2,3, Tang, Baiyou2,4, Xiao, Qiang1, Qu, Rong2,3, Tong, Linjiang2, Liu, Jian1, Ding, Jian2, Chen, Yi2, Ding, Ning1, Tan, Wenfu1 wftan@fudan.edu.cn, Xie, Hua2 hxie@simm.ac.cn, Li, Yingxia1 liyx417@fudan.edu.cn
Source: European Journal of Medicinal Chemistry. May2018, Vol. 152, p298-306. 9p.
Database: Academic Search Ultimate
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  Data: Discovery of novel 2,4-diarylaminopyrimidine derivatives as potent and selective epidermal growth factor receptor (EGFR) inhibitors against L858R/T790M resistance mutation.
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  Data: <searchLink fieldCode="AR" term="%22Yan%2C+Qi%22">Yan, Qi</searchLink><relatesTo>1</relatesTo><br /><searchLink fieldCode="AR" term="%22Chen%2C+Yuzhe%22">Chen, Yuzhe</searchLink><relatesTo>2,3</relatesTo><br /><searchLink fieldCode="AR" term="%22Tang%2C+Baiyou%22">Tang, Baiyou</searchLink><relatesTo>2,4</relatesTo><br /><searchLink fieldCode="AR" term="%22Xiao%2C+Qiang%22">Xiao, Qiang</searchLink><relatesTo>1</relatesTo><br /><searchLink fieldCode="AR" term="%22Qu%2C+Rong%22">Qu, Rong</searchLink><relatesTo>2,3</relatesTo><br /><searchLink fieldCode="AR" term="%22Tong%2C+Linjiang%22">Tong, Linjiang</searchLink><relatesTo>2</relatesTo><br /><searchLink fieldCode="AR" term="%22Liu%2C+Jian%22">Liu, Jian</searchLink><relatesTo>1</relatesTo><br /><searchLink fieldCode="AR" term="%22Ding%2C+Jian%22">Ding, Jian</searchLink><relatesTo>2</relatesTo><br /><searchLink fieldCode="AR" term="%22Chen%2C+Yi%22">Chen, Yi</searchLink><relatesTo>2</relatesTo><br /><searchLink fieldCode="AR" term="%22Ding%2C+Ning%22">Ding, Ning</searchLink><relatesTo>1</relatesTo><br /><searchLink fieldCode="AR" term="%22Tan%2C+Wenfu%22">Tan, Wenfu</searchLink><relatesTo>1</relatesTo><i> wftan@fudan.edu.cn</i><br /><searchLink fieldCode="AR" term="%22Xie%2C+Hua%22">Xie, Hua</searchLink><relatesTo>2</relatesTo><i> hxie@simm.ac.cn</i><br /><searchLink fieldCode="AR" term="%22Li%2C+Yingxia%22">Li, Yingxia</searchLink><relatesTo>1</relatesTo><i> liyx417@fudan.edu.cn</i>
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  Data: <searchLink fieldCode="JN" term="%22European+Journal+of+Medicinal+Chemistry%22">European Journal of Medicinal Chemistry</searchLink>. May2018, Vol. 152, p298-306. 9p.
PLink https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=asn&AN=129714371
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      – Type: doi
        Value: 10.1016/j.ejmech.2018.04.052
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      – Code: eng
        Text: English
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        PageCount: 9
        StartPage: 298
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      – TitleFull: Discovery of novel 2,4-diarylaminopyrimidine derivatives as potent and selective epidermal growth factor receptor (EGFR) inhibitors against L858R/T790M resistance mutation.
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            NameFull: Yan, Qi
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            NameFull: Chen, Yuzhe
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            – D: 25
              M: 05
              Text: May2018
              Type: published
              Y: 2018
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              Value: 02235234
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              Value: 152
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