Dependence on the Pyrimidine Biosynthetic Enzyme DHODH Is a Synthetic Lethal Vulnerability in Mutant KRAS-Driven Cancers.
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| Title: | Dependence on the Pyrimidine Biosynthetic Enzyme DHODH Is a Synthetic Lethal Vulnerability in Mutant KRAS-Driven Cancers. |
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| Authors: | Koundinya, Malvika1, Sudhalter, Judith1, Courjaud, Albane2, Lionne, Bruno2, Touyer, Gaetan2, Bonnet, Luc2, Menguy, Isabelle2, Schreiber, Isabelle2, Perrault, Christelle2, Vougier, Stephanie2, Benhamou, Brigitte2, Zhang, Bailin3, He, Timothy3, Gao, Qiang3, Gee, Patricia3, Simard, Daniel3,4, Castaldi, M. Paola4, Tomlinson, Ronald4, Reiling, Stephan5, Barrague, Matthieu6 |
| Source: | Cell Chemical Biology. Jun2018, Vol. 25 Issue 6, p705-717.e11. 1p. |
| Database: | Academic Search Ultimate |
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