445TiPComprehensive profiling and molecularly guided therapy (MGT) for carcinomas of unknown primary (CUP): CUPISCO: A phase II, randomised, multicentre study comparing targeted therapy or immunotherapy with standard platinum-based chemotherapy. - Krämer, A; Losa, F; Gay, L M; Page, D R; Foser, S; Mughal, T I; Ross, J S; Baciarello, G; Mileshkin, L R; Osborne, S (Annals of Oncology, 2018)