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Discovery and optimization of novel pyridines as highly potent and selective glycogen synthase kinase 3 inhibitors.

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Title: Discovery and optimization of novel pyridines as highly potent and selective glycogen synthase kinase 3 inhibitors.
Authors: Ramurthy, Savithri1 (AUTHOR), Pfister, Keith B.2 (AUTHOR), Boyce, Rustum S.3 (AUTHOR), Brown, Sean P.4 (AUTHOR), Costales, Abran Q.5 (AUTHOR), Desai, Manoj C.6 (AUTHOR), Fang, Eric7 (AUTHOR), Levine, Barry H.8 (AUTHOR), Ng, Simon C.9 (AUTHOR), Nuss, John M.10 (AUTHOR), Ring, David B.11 (AUTHOR), Shafer, Cynthia M.12 (AUTHOR), Shu, Wei2 (AUTHOR), Subramanian, Sharadha13 (AUTHOR), Wagman, Allan S.14 (AUTHOR), Wang, Haixia15 (AUTHOR), Bussiere, Dirksen E.1,2 (AUTHOR) dirksen.bussiere@novartis.com
Source: Bioorganic & Medicinal Chemistry Letters. Feb2020, Vol. 30 Issue 4, pN.PAG-N.PAG. 1p.
Database: Academic Search Ultimate
Description
ISSN:0960894X
DOI:10.1016/j.bmcl.2019.126930