Infection with multiple HIV-1 founder variants is associated with lower viral replicative capacity, faster CD4+ T cell decline and increased immune activation during acute infection.

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Title: Infection with multiple HIV-1 founder variants is associated with lower viral replicative capacity, faster CD4+ T cell decline and increased immune activation during acute infection.
Authors: Macharia, Gladys N.1,2 (AUTHOR), Yue, Ling3 (AUTHOR), Staller, Ecco1,2 (AUTHOR), Dilernia, Dario3 (AUTHOR), Wilkins, Daniel3 (AUTHOR), Song, Heeyah3 (AUTHOR), McGowan, Edward1,2 (AUTHOR), King, Deborah1,2 (AUTHOR), Fast, Pat4 (AUTHOR), Imami, Nesrina1 (AUTHOR), Price, Matthew A.4,5 (AUTHOR), Sanders, Eduard J.6,7 (AUTHOR), Hunter, Eric3,8 (AUTHOR), Gilmour, Jill1,2 (AUTHOR) JGilmour@iavi.org
Source: PLoS Pathogens. 9/4/2020, Vol. 16 Issue 9, p1-22. 22p.
Database: Academic Search Ultimate
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ISSN:15537366
DOI:10.1371/journal.ppat.1008853