High-throughput screening of the ReFRAME, Pandemic Box, and COVID Box drug repurposing libraries against SARS-CoV-2 nsp15 endoribonuclease to identify small-molecule inhibitors of viral activity.

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Title: High-throughput screening of the ReFRAME, Pandemic Box, and COVID Box drug repurposing libraries against SARS-CoV-2 nsp15 endoribonuclease to identify small-molecule inhibitors of viral activity.
Authors: Choi, Ryan1 (AUTHOR), Zhou, Mowei2 (AUTHOR), Shek, Roger1,3 (AUTHOR), Wilson, Jesse W.2 (AUTHOR), Tillery, Logan1,3 (AUTHOR), Craig, Justin K.1,3 (AUTHOR), Salukhe, Indraneel A.4 (AUTHOR), Hickson, Sarah E.4 (AUTHOR), Kumar, Neeraj2 (AUTHOR), James, Rhema M.2 (AUTHOR), Buchko, Garry W.2,3,5 (AUTHOR), Wu, Ruilian6 (AUTHOR), Huff, Sydney1 (AUTHOR), Nguyen, Tu-Trinh7 (AUTHOR), Hurst, Brett L.8 (AUTHOR), Cherry, Sara9 (AUTHOR), Barrett, Lynn K.1,3 (AUTHOR), Hyde, Jennifer L.4 (AUTHOR), Van Voorhis, Wesley C.1,3,4,10 (AUTHOR) wesley@uw.edu
Source: PLoS ONE. 4/22/2021, Vol. 16 Issue 4, p1-25. 25p.
Database: Academic Search Ultimate
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ISSN:19326203
DOI:10.1371/journal.pone.0250019