Protective CD4+ Th1 cell-mediated immunity is reliant upon execution of effector function prior to the establishment of the pathogen niche. - Hohman, Leah S.; Mou, Zhirong; Carneiro, Matheus B.; Ferland, Gabriel; Kratofil, Rachel M.; Kubes, Paul; Uzonna, Jude E.; Peters, Nathan C. (PLoS Pathogens, 2021)