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A novel glucosylceramide synthase inhibitor attenuates alpha synuclein pathology and lysosomal dysfunction in preclinical models of synucleinopathy.

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Title: A novel glucosylceramide synthase inhibitor attenuates alpha synuclein pathology and lysosomal dysfunction in preclinical models of synucleinopathy.
Authors: Cosden, Mali1 (AUTHOR), Jinn, Sarah1 (AUTHOR), Yao, Lihang1 (AUTHOR), Gretzula, Cheryl A.1 (AUTHOR), Kandebo, Monika1 (AUTHOR), Toolan, Dawn1 (AUTHOR), Hatcher, Nathan G.1 (AUTHOR), Ma, Lei1 (AUTHOR), Lemaire, Wei2 (AUTHOR), Adam, Gregory C.2 (AUTHOR), Burlein, Christine2 (AUTHOR), Minnick, Christina2 (AUTHOR), Flick, Rose2 (AUTHOR), Watt, Marla L.2 (AUTHOR), Mulhearn, James3 (AUTHOR), Fraley, Mark3 (AUTHOR), Drolet, Robert E.1 (AUTHOR), Marcus, Jacob N.1 (AUTHOR), Smith, Sean M.1 (AUTHOR) sean_smith2@merck.com
Source: Neurobiology of Disease. Nov2021, Vol. 159, pN.PAG-N.PAG. 1p.
Database: Academic Search Ultimate
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Header DbId: asn
DbLabel: Academic Search Ultimate
An: 152816107
AccessLevel: 2
PubType: Academic Journal
PubTypeId: academicJournal
PreciseRelevancyScore: 0
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  Data: A novel glucosylceramide synthase inhibitor attenuates alpha synuclein pathology and lysosomal dysfunction in preclinical models of synucleinopathy.
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  Data: <searchLink fieldCode="JN" term="%22Neurobiology+of+Disease%22">Neurobiology of Disease</searchLink>. Nov2021, Vol. 159, pN.PAG-N.PAG. 1p.
PLink https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=asn&AN=152816107
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      – Type: doi
        Value: 10.1016/j.nbd.2021.105507
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      – Code: eng
        Text: English
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              M: 11
              Text: Nov2021
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              Y: 2021
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