The mismatched nucleotides encoded in vaccinia virus flip-and-flop hairpin telomeres serve an essential role in virion maturation. - Shenouda, Mira M.; Noyce, Ryan S.; Lee, Stephen Z.; Wang, Jun Li; Lin, Yi-Chan; Favis, Nicole A.; Desaulniers, Megan A.; Evans, David H. (PLoS Pathogens, 2022)