A homing suppression gene drive with multiplexed gRNAs maintains high drive conversion efficiency and avoids functional resistance alleles.

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Title: A homing suppression gene drive with multiplexed gRNAs maintains high drive conversion efficiency and avoids functional resistance alleles.
Authors: Yang, Emily1,2, Metzloff, Matthew1,2, Langmüller, Anna M.1,3,4, Xuejiao Xu5, Clark, Andrew G.1,2, Messer, Philipp W.1, Champer, Jackson1,2,5 jchamper@pku.edu.cn
Source: G3: Genes | Genomes | Genetics. Jun2022, Vol. 12 Issue 6, p1-13. 13p.
Database: Academic Search Ultimate
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DbLabel: Academic Search Ultimate
An: 157379448
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  Data: A homing suppression gene drive with multiplexed gRNAs maintains high drive conversion efficiency and avoids functional resistance alleles.
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  Data: <searchLink fieldCode="AR" term="%22Yang%2C+Emily%22">Yang, Emily</searchLink><relatesTo>1,2</relatesTo><br /><searchLink fieldCode="AR" term="%22Metzloff%2C+Matthew%22">Metzloff, Matthew</searchLink><relatesTo>1,2</relatesTo><br /><searchLink fieldCode="AR" term="%22Langmüller%2C+Anna+M%2E%22">Langmüller, Anna M.</searchLink><relatesTo>1,3,4</relatesTo><br /><searchLink fieldCode="AR" term="%22Xuejiao+Xu%22">Xuejiao Xu</searchLink><relatesTo>5</relatesTo><br /><searchLink fieldCode="AR" term="%22Clark%2C+Andrew+G%2E%22">Clark, Andrew G.</searchLink><relatesTo>1,2</relatesTo><br /><searchLink fieldCode="AR" term="%22Messer%2C+Philipp+W%2E%22">Messer, Philipp W.</searchLink><relatesTo>1</relatesTo><br /><searchLink fieldCode="AR" term="%22Champer%2C+Jackson%22">Champer, Jackson</searchLink><relatesTo>1,2,5</relatesTo><i> jchamper@pku.edu.cn</i>
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  Data: <searchLink fieldCode="JN" term="%22G3%3A+Genes+|+Genomes+|+Genetics%22">G3: Genes | Genomes | Genetics</searchLink>. Jun2022, Vol. 12 Issue 6, p1-13. 13p.
PLink https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=asn&AN=157379448
RecordInfo BibRecord:
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      – Type: doi
        Value: 10.1093/g3journal/jkac081
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      – Code: eng
        Text: English
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      Pagination:
        PageCount: 13
        StartPage: 1
    Titles:
      – TitleFull: A homing suppression gene drive with multiplexed gRNAs maintains high drive conversion efficiency and avoids functional resistance alleles.
        Type: main
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      – PersonEntity:
          Name:
            NameFull: Yang, Emily
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            NameFull: Metzloff, Matthew
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            NameFull: Langmüller, Anna M.
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            NameFull: Xuejiao Xu
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            NameFull: Clark, Andrew G.
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            NameFull: Messer, Philipp W.
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            NameFull: Champer, Jackson
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          Dates:
            – D: 01
              M: 06
              Text: Jun2022
              Type: published
              Y: 2022
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              Value: 21601836
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              Value: 12
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              Value: 6
          Titles:
            – TitleFull: G3: Genes | Genomes | Genetics
              Type: main
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