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Fifteen years of NaV1.7 channels as an analgesic target: Why has excellent in vitro pharmacology not translated into in vivo analgesic efficacy?

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Title: Fifteen years of NaV1.7 channels as an analgesic target: Why has excellent in vitro pharmacology not translated into in vivo analgesic efficacy?
Authors: Eagles, David A.1 (AUTHOR), Chow, Chun Yuen1 (AUTHOR), King, Glenn F.1 (AUTHOR) glenn.king@imb.uq.edu.au
Source: British Journal of Pharmacology. Jul2022, Vol. 179 Issue 14, p3592-3611. 20p. 3 Diagrams, 5 Charts.
Database: Academic Search Ultimate
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ISSN:00071188
DOI:10.1111/bph.15327