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Fragment screening using biolayer interferometry reveals ligands targeting the SHP-motif binding site of the AAA+ ATPase p97.

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Title: Fragment screening using biolayer interferometry reveals ligands targeting the SHP-motif binding site of the AAA+ ATPase p97.
Authors: Bothe, Sebastian1,2 (AUTHOR), Hänzelmann, Petra2 (AUTHOR), Böhler, Stephan1,2 (AUTHOR), Kehrein, Josef1 (AUTHOR), Zehe, Markus1 (AUTHOR), Wiedemann, Christoph3 (AUTHOR), Hellmich, Ute A.3,4,5 (AUTHOR), Brenk, Ruth6 (AUTHOR), Schindelin, Hermann2 (AUTHOR) hermann.schindelin@virchow.uni-wuerzburg.de, Sotriffer, Christoph1 (AUTHOR) sotriffer@uni-wuerzburg.de
Source: Communications Chemistry. 12/7/2022, Vol. 5 Issue 1, p1-15. 15p.
Database: Academic Search Ultimate
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ISSN:23993669
DOI:10.1038/s42004-022-00782-5