BCI-838, an orally active mGluR2/3 receptor antagonist pro-drug, rescues learning behavior deficits in the PS19 MAPTP301S mouse model of tauopathy.

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Title: BCI-838, an orally active mGluR2/3 receptor antagonist pro-drug, rescues learning behavior deficits in the PS19 MAPTP301S mouse model of tauopathy.
Authors: Perez-Garcia, Georgina1,2 (AUTHOR), Bicak, Mesude3,4 (AUTHOR), Haure-Mirande, Jean-Vianney1 (AUTHOR), Perez, Gissel M.2 (AUTHOR), Otero-Pagan, Alena2 (AUTHOR), Gama Sosa, Miguel A.5,6 (AUTHOR), De Gasperi, Rita2,5 (AUTHOR), Sano, Mary2,5,7 (AUTHOR), Barlow, Carrolee8,9 (AUTHOR), Gage, Fred H.8,10 (AUTHOR), Readhead, Benjamin11 (AUTHOR), Ehrlich, Michelle E.1,3 (AUTHOR), Gandy, Sam1,2,5,7,12 (AUTHOR), Elder, Gregory A.1,5,7,13 (AUTHOR) gregory.elder@mssm.edu
Source: Neuroscience Letters. Feb2023, Vol. 797, pN.PAG-N.PAG. 1p.
Database: Academic Search Ultimate
Description
ISSN:03043940
DOI:10.1016/j.neulet.2023.137080