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Stereochemical engineering yields a multifunctional peptide macrocycle inhibitor of Akt2 by fine-tuning macrocycle-cell membrane interactions.

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Bibliographic Details
Title: Stereochemical engineering yields a multifunctional peptide macrocycle inhibitor of Akt2 by fine-tuning macrocycle-cell membrane interactions.
Authors: Nag, Arundhati1,2 (AUTHOR), Mafi, Amirhossein3 (AUTHOR), Das, Samir1,2 (AUTHOR), Yu, Mary Beth1 (AUTHOR), Alvarez-Villalonga, Belen1 (AUTHOR), Kim, Soo-Kyung3 (AUTHOR), Su, Yapeng1,4 (AUTHOR), Goddard III, William A.3 (AUTHOR), Heath, James R.1,4 (AUTHOR) jim.heath@isbscience.org
Source: Communications Chemistry. 5/18/2023, Vol. 6 Issue 1, p1-12. 12p.
Database: Academic Search Ultimate
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ISSN:23993669
DOI:10.1038/s42004-023-00890-w