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Diselenide-bond replacement of the external disulfide bond of insulin increases its oligomerization leading to sustained activity.

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Title: Diselenide-bond replacement of the external disulfide bond of insulin increases its oligomerization leading to sustained activity.
Authors: Arai, Kenta1,2 (AUTHOR) k-arai4470@tokai-u.jp, Okumura, Masaki3 (AUTHOR), Lee, Young-Ho4,5,6,7 (AUTHOR), Katayama, Hidekazu8 (AUTHOR), Mizutani, Kenji9 (AUTHOR), Lin, Yuxi4 (AUTHOR), Park, Sam-Yong9 (AUTHOR), Sawada, Kaichiro10 (AUTHOR), Toyoda, Masao10 (AUTHOR), Hojo, Hironobu11 (AUTHOR), Inaba, Kenji12,13 (AUTHOR), Iwaoka, Michio1,2 (AUTHOR) miwaoka@tokai.ac.jp
Source: Communications Chemistry. 11/21/2023, Vol. 6 Issue 1, p1-10. 10p.
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  Data: Diselenide-bond replacement of the external disulfide bond of insulin increases its oligomerization leading to sustained activity.
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  Data: <searchLink fieldCode="AR" term="%22Arai%2C+Kenta%22">Arai, Kenta</searchLink><relatesTo>1,2</relatesTo> (AUTHOR)<i> k-arai4470@tokai-u.jp</i><br /><searchLink fieldCode="AR" term="%22Okumura%2C+Masaki%22">Okumura, Masaki</searchLink><relatesTo>3</relatesTo> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Lee%2C+Young-Ho%22">Lee, Young-Ho</searchLink><relatesTo>4,5,6,7</relatesTo> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Katayama%2C+Hidekazu%22">Katayama, Hidekazu</searchLink><relatesTo>8</relatesTo> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Mizutani%2C+Kenji%22">Mizutani, Kenji</searchLink><relatesTo>9</relatesTo> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Lin%2C+Yuxi%22">Lin, Yuxi</searchLink><relatesTo>4</relatesTo> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Park%2C+Sam-Yong%22">Park, Sam-Yong</searchLink><relatesTo>9</relatesTo> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Sawada%2C+Kaichiro%22">Sawada, Kaichiro</searchLink><relatesTo>10</relatesTo> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Toyoda%2C+Masao%22">Toyoda, Masao</searchLink><relatesTo>10</relatesTo> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Hojo%2C+Hironobu%22">Hojo, Hironobu</searchLink><relatesTo>11</relatesTo> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Inaba%2C+Kenji%22">Inaba, Kenji</searchLink><relatesTo>12,13</relatesTo> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Iwaoka%2C+Michio%22">Iwaoka, Michio</searchLink><relatesTo>1,2</relatesTo> (AUTHOR)<i> miwaoka@tokai.ac.jp</i>
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  Data: <searchLink fieldCode="JN" term="%22Communications+Chemistry%22">Communications Chemistry</searchLink>. 11/21/2023, Vol. 6 Issue 1, p1-10. 10p.
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        Value: 10.1038/s42004-023-01056-4
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              Text: 11/21/2023
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