Unmutated but T cell dependent IgM antibodies targeting Streptococcus suis play an essential role in bacterial clearance. - Dolbec, Dominic; Lehoux, Mélanie; de Beauville, Alexis Asselin; Zahn, Astrid; Di Noia, Javier Marcelo; Segura, Mariela (PLoS Pathogens, 2024)