Structure–activity relationships for the G-quadruplex-targeting experimental drug QN-302 and two analogues probed with comparative transcriptome profiling and molecular modeling.

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Title: Structure–activity relationships for the G-quadruplex-targeting experimental drug QN-302 and two analogues probed with comparative transcriptome profiling and molecular modeling.
Authors: Ahmed, Ahmed Abdullah1,2 (AUTHOR), Chen, Shuang1 (AUTHOR), Roman-Escorza, Maria2 (AUTHOR), Angell, Richard1,3 (AUTHOR), Oxenford, Sally1,4 (AUTHOR), McConville, Matthew5 (AUTHOR), Barton, Naomi6 (AUTHOR), Sunose, Mihiro5 (AUTHOR), Neidle, Dan6 (AUTHOR), Haider, Shozeb1 (AUTHOR), Arshad, Tariq7 (AUTHOR), Neidle, Stephen1 (AUTHOR) s.neidle@ucl.ac.uk
Source: Scientific Reports. 2/15/2024, Vol. 14 Issue 1, p1-13. 13p.
Database: Academic Search Ultimate
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ISSN:20452322
DOI:10.1038/s41598-024-54080-2